Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins

Autor: Verena Dederer, Anton Khmelinskii, Anna Gesine Huhn, Voytek Okreglak, Michael Knop, Marius K Lemberg

Publikováno v: eLife, Vol 8 (2019)

Tail-anchored (TA) proteins insert post-translationally into the endoplasmic reticulum (ER), the outer mitochondrial membrane (OMM) and peroxisomes. Whereas the GET pathway controls ER-targeting, no dedicated factors are known for OMM insertion, posi

Externí odkaz: https://doaj.org/article/c6f8f3892e2d41028bef137849c62e07

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins.

Autor: Dederer V; Centre for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany., Khmelinskii A; Centre for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany., Huhn AG; Centre for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany., Okreglak V; Calico Life Sciences LLC, South San Francisco, United States., Knop M; Centre for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.; Cell Morphogenesis and Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Germany., Lemberg MK; Centre for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.

Publikováno v: ELife [Elife] 2019 Jun 07; Vol. 8. Date of Electronic Publication: 2019 Jun 07.