Zobrazeno 1 - 10
of 75
pro vyhledávání: '"E1A binding protein p300"'
Autor:
Weike Hu
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Sepsis represents an organ dysfunction resulting from the host’s maladjusted response to infection, and can give rise to acute kidney injury (AKI), which significantly increase the morbidity and mortality of septic patients. This study strived for
Externí odkaz:
https://doaj.org/article/483f3a2ef2774013990ee24ef777122e
Autor:
Yihao Liu, Xuelong Wang, Youwei Zhu, Yizhi Cao, Liwen Wang, Fanlu Li, Yu Zhang, Ying Li, Zhiqiang Zhang, Jiaxin Luo, Xiaxing Deng, Chenghong Peng, Gang Wei, Hao Chen, Baiyong Shen
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 2, Pp n/a-n/a (2022)
Abstract Background Tumour‐associated macrophages (TAMs) play an important role in promoting the progression of pancreatic ductal adenocarcinoma (PDAC). Here, we aimed to study the epigenetic mechanisms in regulating pro‐tumour M2‐polarised TAM
Externí odkaz:
https://doaj.org/article/4ee6205d84c64ad8a0ffce74fb3bde24
Autor:
Aleksandar Krstic, Anja Konietzny, Melinda Halasz, Peter Cain, Udo Oppermann, Walter Kolch, David J. Duffy
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Although a rare disease, neuroblastoma accounts for the highest proportion of childhood cancer deaths. There is a lack of recurrent somatic mutations in neuroblastoma embryonal tumours, suggesting a possible role for epigenetic alterations in driving
Externí odkaz:
https://doaj.org/article/2582549fd7904b79b0d0561609b1a9a2
Akademický článek
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Publikováno v:
Cancer Biology & Medicine, Vol 11, Iss 3, Pp 202-207 (2014)
Objective The results of a previous study showed that a clear dysregulation was evident in the global gene expression of the BCL11A-suppressed B-lymphoma cells. In this study, the bone morphogenetic protein receptor, type Ⅱ (BMPR2), E1A binding pro
Externí odkaz:
https://doaj.org/article/ccc4039cf15f4fc0b00241f854a2b9c0
Autor:
Peter H. O'Donnell, Richard Martin Bambury, Richard C. Chao, Joaquim Bellmunt, Elizabeth A. Guancial, Guru Sonpavde, Noah M. Hahn, Joel Picus, Amir Mortazavi, James G. Christensen, Diane Potvin, Demiana Faltaos, Ajjai Alva, Jonathan E. Rosenberg, Petros Grivas, Sumanta K. Pal, Sumati Gupta, Matthew I. Milowsky, Lowell L. Hart
Publikováno v:
Cancer
Background The authors evaluated mocetinostat (a class I/IV histone deacetylase inhibitor) in patients with urothelial carcinoma harboring inactivating mutations or deletions in CREB binding protein [CREBBP] and/or E1A binding protein p300 [EP300] hi
Autor:
Takuya Kajimura, Isao Tamura, Yumiko Doi-Tanaka, Hiroshi Tamura, Yumiko Mihara, Norihiro Sugino, Ryo Maekawa, Shun Sato, Toshiaki Taketani, Yuichiro Shirafuta, Taishi Fujimura, Haruka Takagi
Publikováno v:
The Journal of Biological Chemistry
Human endometrial stromal cells (ESCs) differentiate into decidual cells by the action of progesterone, which is essential for implantation and maintenance of pregnancy. We previously reported that glucose uptake by human ESCs increases during decidu
Publikováno v:
Oncology Reports
Ferroptosis is a new form of regulated cell death and closely related to cancer. However, the mechanism underlying the regulation of ferroptosis in lung adenocarcinoma (LUAD) remains unclear. IB, IHC and ELISA were performed to analyze protein expres
Akademický článek
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Publikováno v:
Oncology Letters
Interleukin (IL)-17A is a T helper (Th)17 cell-secreted cytokine that is able to induce various inflammatory responses. There is emerging evidence that IL-17A is generated in the cancer microenvironment of human nasopharyngeal carcinoma (NPC). Howeve