Zobrazeno 1 - 10
of 46
pro vyhledávání: '"E.V. Dementyeva"'
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102348- (2021)
Hypertrophic cardiomyopathy (HCM) is a frequent cardiovascular pathology caused by a huge number of mutations in sarcomere-associated proteins. This genetic diversity leads to differences in pathogenetic mechanisms and hampers HCM therapy. Cardiomyoc
Externí odkaz:
https://doaj.org/article/9bc2172d50ec4e55b40586922f2b976d
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102344- (2021)
Hypertrophic cardiomyopathy (HCM) is a common cardiovascular disease. However, effective methods of its therapy have not been developed so far. To date patient-specific induced pluripotent stem cell-derived cardiomyocytes are supposed to be a useful
Externí odkaz:
https://doaj.org/article/53c1494a8bd349b5b481b307ae064844
Autor:
E.V. Dementyeva, V.R. Kovalenko, M.K. Zhiven, E.I. Ustyantseva, E.I. Kretov, Yu.V. Vyatkin, S.M. Zakian
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101840- (2020)
Hypertrophic cardiomyopathy (HCM) is one of the most frequent cardiovascular diseases but no methods to prevent its progression have been developed. Cardiomyocytes derived from patient-specific induced pluripotent stem cells can become a platform to
Externí odkaz:
https://doaj.org/article/9fc55c9826544102ae69bba5e91c2a94
Akademický článek
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Autor:
E.V. Dementyeva, S.M. Zakian, M M Slotvitsky, Dmitry Shtokalo, E. A. Pokushalov, V.R. Kovalenko, E.I. Kretov, Sergey P. Medvedev, Yu.V. Vyatkin
Publikováno v:
Biochemistry (Moscow). 84:291-298
Generation of patient-specific induced pluripotent stem cells (iPSCs) and their subsequent differentiation into cardiomyocytes opened new opportunities for studying pathogenesis of inherited cardiovascular diseases. One of these diseases is hypertrop
Publikováno v:
The International Journal of Developmental Biology. 63:223-233
In eutherian mammals, dosage compensation arose to balance X-linked gene expression between sexes and relatively to autosomal gene expression in the evolution of sex chromosomes. Dosage compensation occurs in early mammalian development and comprises
Autor:
E.V. Dementyeva, М.М. Slotvitsky, E. V. Chepeleva, Е.А. Pokushalov, Е.V. Grigor’eva, А.V. Ponomarenko, A.A. Malakhova, D. S. Sergeevichev, E.D. Sorokoumov, S.М. Zakian, А.А. Dokuchaeva, S.V. Pavlova
Publikováno v:
Genes & Cells. 13:51-60
Conduction and heart rhythm disorders can be caused by both functional pathology and severe organic lesions of the heart. The possibility of using cell-based replacement cell therapy derived from induced pluripotent stem cells to compensate for lost
Autor:
E. A. Elisaphenko, Konstantin Agladze, E. A. Pokushalov, E.V. Dementyeva, Sevda Bayramova, Sergey P. Medvedev, Suren M. Zakian
Publikováno v:
Genes & Cells. 13:75-80
Genetic analysis plays an important role in diagnostics of cardiovascular diseases. One of the diseases is long QT syndrome that results in an increased risk of ventricular tachycardia and sudden cardiac death. The syndrome may be caused by mutations
Autor:
Alexander I. Shevchenko, E.V. Dementyeva, Sergey P. Medvedev, A.A. Malakhova, E.V. Grigor'eva, Eugeny A. Elisaphenko, Irina S. Zakharova, S. V. Pavlova, Suren M. Zakian
Publikováno v:
Chromosoma. 127:129-139
In vole Microtus levis, cells of preimplantation embryo and extraembryonic tissues undergo imprinted X chromosome inactivation (iXCI) which is triggered by a long non-coding nuclear RNA, Xist. At early stages of iXCI, chromatin of vole inactive X chr
Autor:
K.R. Valetdinova, E.V. Dementyeva, V. A. Tsvelaya, A. D. Podgurskaya, M. M. Slotvitsky, Konstantin Agladze
Erythromycin is an antibiotic that prolongs the QT-interval and causes Torsade de Pointes (TdP) by blocking the rapid delayed rectifying potassium current (IKr) without affecting either the slow delayed rectifying potassium current (IKs) or inward re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e50e48b401168fe3dbaaef0d5128ed
https://doi.org/10.1101/574012
https://doi.org/10.1101/574012