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pro vyhledávání: '"E.S. Severin"'
Publikováno v:
Experimental Neurobiology
To compare the efficacy of L-DOPA administered intranasally in the form of nanoparticles (nano-DOPA) and in standard drug forms using a rat Parkinson's Disease (PD) model. L-DOPA-containing nanoparticles (250±50 nm) were synthesized using the double
Publikováno v:
Journal of the Neurological Sciences. 333:e97
Publikováno v:
Immunotherapeutic Prospects of Infectious Diseases ISBN: 9783642761225
The directed or targeted transport of drugs to sites of disease was first suggested by Ehrlich more than 100 years ago (Himmelweit, 1960). There is no doubt that drugs are most effective, and have fewest side effects, when their activity becomes mani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3005d16f514af0b55294fd608bbb69f
https://doi.org/10.1007/978-3-642-76120-1_53
https://doi.org/10.1007/978-3-642-76120-1_53
Akademický článek
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Autor:
E.S. Severin, D.J. Tildesley
Publikováno v:
Molecular Physics. 41:1401-1418
In this paper we present a molecular dynamics study of a methane molecule adsorbed on a graphite surface. The methane is modelled using five interaction sites and the surface is an infinite hexagonal array of carbon atoms. The potential parameters ar
Publikováno v:
Chemical Physics Letters. 57:117-120
A new microcanonical sampling procedure is presented which incorporates much of the simplicity and efficiency of the canonical procedures. Comparison with previous procedures indicates that the gain in efficiency is substantial. The relevance to nume
Publikováno v:
FEBS Letters. 84:163-166
Publikováno v:
Neuroscience. 32:261-268
Primary cultures of human embryo brain cells (9–12 weeks of pregnancy) were obtained. The use of selective substrates (poly- l -lysine, poly- l -ornithine, reconstructed collagen) made it possible to obtain neuron-rich (up to 80%) cultures viable f
Publikováno v:
Advances in Enzyme Regulation. 17:251-282
The catalytic subunit of cyclic AMP-dependent protein kinase was isolated from pigeon breast muscle. The enzyme was 11,000-fold purified and, according to the data of SDS polyacrylamide gel electrophoresis, the enzyme preparation obtained was homogen
Autor:
V. Tomášek, E.S. Severin
Publikováno v:
Biochemical and Biophysical Research Communications. 20:496-502