Zobrazeno 1 - 10
of 101
pro vyhledávání: '"E.S. Redgate"'
Autor:
E.S. Redgate, Sallie S. Boggs, T. Ryan Magra, Joseph S. Henretty, Dominic Alexander, Kenneth D. Patrene
Publikováno v:
Journal of Neuro-Oncology. 55:71-80
Polyamine synthesis inhibitors, such as α-difluoromethylornithine (DFMO), inhibit tumor cell growth in vitro and in vivo. However, upon cessation of treatment, tumor growth resumes. We hypothesized that incorporation of radioactive polyamines might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b7bf4ff0e9025498a93c944a010e5b
https://doi.org/10.1023/a:1013348227892
https://doi.org/10.1023/a:1013348227892
Autor:
Rina Kashi, Xavier Filella, Yu-Hsueh Wang, Marianne Grob, Pablo Carretero, Yoshikazu Hayatsu, Yoshihisa Fujikura, Rafael Molina, Keith Sides, Paul M. Sondel, Rosalyn D. Blumenthal, David M. Goldenberg, Sallie S. Boggs, Fumihiko Shinozaki, M. Deutsch, Rhona Stein, Xinwei Li, Tetsuo Fukumoto, Rehana Sultana Lovely, Nobuko Tokuda, Dawn H. Siegel, Patrizia Lorenzoni, E.S. Redgate, Antonio M. Ballesta, Max M. Burger, C.M. Nicolet, Dorit Goren, Alfredo Rodríguez, Tomoo Sawada, J.E. Surfus, Juan Alcover, A. Gabryel-Grudziak, Robert M. Sharkey
Publikováno v:
Tumor Biology. 18:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5edc1caf00d9f247675696864cfd5a
https://doi.org/10.1159/000218045
https://doi.org/10.1159/000218045
Publikováno v:
Tumor Biology. 18:321-331
Several laboratories have introduced the lacZ gene into 9L cells to improve the usefulness of this already popular rat brain tumor model. However, these laboratories were not concerned about possible changes in the phenotypic characteristics of the 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a477735b8e4debc8215d0e1916313bb0
https://doi.org/10.1159/000218046
https://doi.org/10.1159/000218046
Publikováno v:
Radiation Oncology Investigations. 1:325-333
The present studies were done to test the hypothesis that the cytostasis caused by D,L-α-difluoromethylornithine (DFMO) would enhance cellular retention of [3H] thymidine and thereby increase the effective internal radiation dose and cell killing. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430251cf8eb04b5a12a1e34b7b34bd35
https://doi.org/10.1002/roi.2970010604
https://doi.org/10.1002/roi.2970010604
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 19:85-87
The efficacy of 5-iodo-2-deoxyuridine (IUDR) as a radiosensitizer when administered by continuous infusion into the cerebral spinal fluid (CSF) of the lateral cerebral ventricle was evaluated in a 9L gliosarcoma rat brain tumor model. Stereotactic im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b4ac3bb648fa5e739df00340504633
https://doi.org/10.1016/0360-3016(90)90138-a
https://doi.org/10.1016/0360-3016(90)90138-a
Publikováno v:
International journal of radiation oncology, biology, physics. 38(1)
Difluoromethylornithine (DFMO) depletes endogenous putrescine and enhances the uptake of and retention of [3H] putrescine in vitro. To determine if DFMO also enhances uptake of [3H] putrescine in vivo, DFMO and trace doses of [3H] putrescine, dissolv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7caa54c0fd1d602438043d439eec79e
https://pubmed.ncbi.nlm.nih.gov/9212020
https://pubmed.ncbi.nlm.nih.gov/9212020
Publikováno v:
Journal of neuro-oncology. 25(2)
In the search for ways to augment current brain tumor therapies many have sought to exploit the fact that adult brain tissue is virtually lacking in cell division. This endorses a special appeal to therapeutic approaches which target the dependence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c05a5771558e534c67fc22f9f7e4a0
https://pubmed.ncbi.nlm.nih.gov/8543973
https://pubmed.ncbi.nlm.nih.gov/8543973
Publikováno v:
International journal of radiation oncology, biology, physics. 25(4)
Purpose : This study explored the possible use of D,L-α-difluoromethylornithine (DFMO) to enhance the uptake of [3H] putrescine in order to selectively kill brain tumor cells. Methods and Materials : Gliosarcoma cells (9L) were grown for 4 or 20 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c7315cac9a7f2948fed05d00731e82
https://pubmed.ncbi.nlm.nih.gov/8454482
https://pubmed.ncbi.nlm.nih.gov/8454482