Zobrazeno 1 - 10
of 193
pro vyhledávání: '"E.R. Huehns"'
Autor:
E.R. Huehns, John B. Porter
Publikováno v:
Acta Haematologica. 78:198-205
The relationship between the number of units of blood transfused and indicators of iron status in 37 patients with sickle cell anaemia (Hb SS), SC disease (Hb SC) or S beta-thalassaemia has been studied. The correlation coefficient between serum ferr
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 10:261-270
Glucose, when incubated with fibrinogen, binds covalently to that protein. The reaction is non-enzymatic in type and is directly dependant on the time of incubation, temperature and pH. Glucosylation of fibrinogen is not altered by preincubation with
Autor:
J.B. Porter, E.R. Huehns
Publikováno v:
Baillière's Clinical Haematology. 2:459-474
DF has a low general toxicity, perhaps because of its low lipid solubility, Kpart 0.01 (Porter et al, 1988b). This feature of the molecule may prevent it from penetrating most cells of the body. It appears that there may be a specific mechanism of up
Autor:
E.R. Huehns, Robert Marcus
Publikováno v:
Clinical & Laboratory Haematology. 7:195-212
Publikováno v:
Baillière's Clinical Haematology. 2:257-292
Studies over the past few years have shown that it is possible to develop iron chelating agents that are active when given by mouth. Such compounds need to have a high binding constant for Fe(III) and an intermediate water and lipid solubility of bot
Publikováno v:
Acta Haematologica. 73:22-25
Four possible methods of preparing young red cells (YRBC) which exploit the relationship between red cell ageing and density are compared. Of these, two cell separators and the IBM cell washer are shown to be capable of producing YRBC suitable for cl
Autor:
E.R. Huehns
Publikováno v:
Clinics in Endocrinology and Metabolism. 5:651-674
Summary An important outcome of the study of abnormalities of glucose metabolism in the red cells has been a greater understanding of the modulating effect of 2,3-DPG on the oxygen affinity of blood as well as the relationship of oxygen affinity to e
Autor:
K.H. Winterhalter, E.R. Huehns
Publikováno v:
Journal of Biological Chemistry. 239:3699-3705
Autor:
E. Bottini, E.R. Huehns
Publikováno v:
Clinica Chimica Acta. 8:127-132
A Chromatographic method for the separation of the non-haemoglobin proteins from the haemoglobin of red cells is reported. The pattern obtained on electrophoresis of this Chromatographic fraction on cellulose acetate and starch gel is described. By u
Publikováno v:
Biochemical and Biophysical Research Communications. 5:362-366
Although the in vivo occurrence of haemoglobins which do not contain α-chains, namely haemoglobin H (β4A) ( Gouttas et al., 1955 ; Rigas et al., 1956 ; Jones et al., 1959 ) and haemoglobin “Bart's” (γ4F) ( Ager and Lehmann, 1958 ; Hunt and Leh