Zobrazeno 1 - 10 of 54 pro vyhledávání: '"E.L.G.M. Tonnaer"'
1
NINL and DZANK1 co-function in vesicle transport and are essential for photoreceptor development in Zebrafish
Autor: Judith G.M. Bergboer, Margo Dona, Nicola Horn, Hannie Kremer, Erwin van Wijk, Ralph Slijkerman, Toby J. Gibson, Theo A. Peters, Jan E.E. Keunen, Sylvia E. C. van Beersum, Gert Flik, Yves Texier, Jeroen van Reeuwijk, Erik de Vrieze, Ruxandra Bachmann-Gagescu, E.L.G.M. Tonnaer, Marius Ueffing, Karsten Boldt, Ronald Roepman, Lisette Hetterschijt, Grischa Toedt
Publikováno v: Plos Genetics, 11, 10
PLoS Genetics
Plos Genetics, 11, e1005574
Plos Genetics, 11
PLoS Genetics, Vol 11, Iss 10, p e1005574 (2015)
Plos Genetics, 11, 10, pp. e1005574
Ciliopathies are Mendelian disorders caused by dysfunction of cilia, ubiquitous organelles involved in fluid propulsion (motile cilia) or signal transduction (primary cilia). Retinal dystrophy is a common phenotypic characteristic of ciliopathies sin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412ace25f2fdc8313b456020659e52db
https://doi.org/10.5167/uzh-116190
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2
The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking
Autor: Marius Ueffing, Erwin van Wijk, Karsten Boldt, Dan Doherty, Lisette Hetterschijt, Stephan C.F. Neuhauss, Ronald Roepman, Hannie Kremer, Ruxandra Bachmann-Gagescu, Theo A. Peters, Ian G. Phelps, Erik de Vrieze, E.L.G.M. Tonnaer, Sylvia E. C. van Beersum, Jan E.E. Keunen, Heleen H. Arts, Cecilia B. Moens, Margo Dona, Dorus A. Mans
Publikováno v: PLoS Genetics, Vol 11, Iss 10, p e1005575 (2015)
Plos Genetics, 11, e1005575
Plos Genetics, 11, 10, pp. e1005575
PLoS Genetics
Ciliopathies are a group of human disorders caused by dysfunction of primary cilia, ubiquitous microtubule-based organelles involved in transduction of extra-cellular signals to the cell. This function requires the concentration of receptors and chan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cf8ca191d62bd0379d9e8393491bea
http://europepmc.org/articles/PMC4617701?pdf=render
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3
Involvement of glycosaminoglycans in the attachment of pneumococci to nasopharyngeal epithelial cells
Autor: J.H.A.J. Curfs, Theo Hafmans, Elisabeth A. M. Sanders, Paul E. Verweij, E.L.G.M. Tonnaer, Toine H. Van Kuppevelt
Publikováno v: Microbes and Infection, 8, 2, pp. 316-22
Microbes and Infection, 8, 316-22
Contains fulltext : 51290.pdf (Publisher’s version ) (Closed access) Streptococcus pneumoniae is a major bacterial pathogen involved in the development of otitis media. The pathogenic mechanisms of this middle ear disease, including the bacterial a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80a4d9e5fe1ab21cf5418f30af1d1ce
https://hdl.handle.net/2066/51290
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4
Genetic relatedness between pneumococcal populations originating from the nasopharynx, adenoid, and tympanic cavity of children with otitis media
Autor: Peter W. M. Hermans, Debby Bogaert, Ger T. Rijkers, E.L.G.M. Tonnaer, Jacques F. Meis, J.H.A.J. Curfs, Corné H. W. Klaassen
Publikováno v: Journal of Clinical Microbiology, 43(7), 3140-3144. American Society for Microbiology
Journal of Clinical Microbiology, 43, 3140-4
Journal of Clinical Microbiology, 43, 7, pp. 3140-4
Previous studies have shown that Streptococcus pneumoniae exists in both middle ear effusions and the upper respiratory region from children with otitis media with effusion (OME), but it remains unclear whether these strains represent genetically ide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09af6c3d4c11745f847871a132d3569e
https://pure.eur.nl/en/publications/e9521b8b-8250-4907-8b37-a7342d2cfac9
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5
Antigenic as well as nonantigenic stimuli induce similar middle ear responses in the rat
Autor: J.H.A.J. Curfs, Ger T. Rijkers, E.L.G.M. Tonnaer, Koen J. A. O. Ingels
Publikováno v: Laryngoscope, 113, 2, pp. 322-7
Laryngoscope, 113, 322-7
Contains fulltext : 139980.pdf (Publisher’s version ) (Closed access) OBJECTIVES/HYPOTHESIS: The observation that during otitis media many different types of micro-organisms have been cultured from effusions indicate that, once present in the middl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d97cab5280a645c93f9dfbae151ead4
https://hdl.handle.net/2066/139980
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6
Effect of Exogenous Surfactant on Ventilatory and Clearance Function of the Rat's Eustachian Tube
Autor: Niels van Heerbeek, Cor W. R. J. Cremers, E.L.G.M. Tonnaer, Koen J. A. O. Ingels, J.H.A.J. Curfs
Publikováno v: Otology & Neurotology, 24, 1, pp. 6-10
Otology & Neurotology, 24, 6-10
Hypothesis and Background: The Eustachian tube has three important functions with respect to the middle ear: ventilation, clearance, and protection. Surfactants are assumed to be important to maintain these functions. The administration of exogenous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acda05446fc2aa9e2b9cfd5329fef25e
https://doi.org/10.1097/00129492-200301000-00003
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7
Changes in ultrastructural characteristics of endolymphatic sac ribosome-rich cells of the rat during development
Autor: E.L.G.M. Tonnaer, J.H.A.J. Curfs, Theo A. Peters, Wim Kuijpers
Publikováno v: Hearing Research, 176, 94-104
Hearing Research, 176, pp. 94-104
It has recently been demonstrated that endolymphatic sac (ES) ribosome-rich (dark) cells respond to induced endolymph changes and are thus likely to be involved in endolymph homeostasis. Therefore, we studied the ultrastructural characteristics of ra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca10080f8d60b5c5e67aacb20e2f421
https://hdl.handle.net/2066/139982
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8
Bacterial otitis media: a new non-invasive rat model
Autor: E.L.G.M. Tonnaer, Elisabeth A. M. Sanders, J.H.A.J. Curfs
Publikováno v: Vaccine, 21, 31, pp. 4539-44
Vaccine, 21, 4539-44
Contains fulltext : 139981.pdf (Publisher’s version ) (Closed access) This study describes the development of a physiological rat model for otitis media. The model is based on the assumption that bacteria, intranasally introduced into the nasophary
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8349237dc1e28d99fa7e11919253a543
https://doi.org/10.1016/s0264-410x(03)00501-2
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9
A comprehensive model for the aetiology of otitis media with effusion
Autor: K.J.A.O. Ingels, E.L.G.M. Tonnaer, G.T. Rijkers, Masja Straetemans, Gerhard A. Zielhuis, N. van Heerbeek
Publikováno v: Medical Hypotheses, 57, 784--91
Medical Hypotheses, 57, 6, pp. 784--91
Item does not contain fulltext Otitis media with effusion is highly prevalent among young children. Adverse effects of this disorder are mainly restricted to the group of children with a history of recurrent or persistent otitis media with effusion.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d76054ca5c428e595c0aae61c5cfd64
https://doi.org/10.1054/mehy.2001.1494
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10
Middle Ear Effusions and Structure of the Tympanic Membrane
Autor: Theo A. Peters, Wim Kuijpers, J.H.A.J. Curfs, E.L.G.M. Tonnaer, Eize W. J. Wielinga
Publikováno v: Laryngoscope, 111, 1, pp. 90-5-5
Laryngoscope, 111, 90-5-5
Item does not contain fulltext OBJECTIVE: To study the effect of various middle ear effusions on the structure of the lamina propria of the tympanic membrane. METHODS: Sterile and infective middle ear effusions were induced by obstruction of the eust
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f811c16a39f0f195a700b5c296b3e5
https://doi.org/10.1097/00005537-200101000-00016
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