Zobrazeno 1 - 10
of 169
pro vyhledávání: '"E.J. Stott"'
Autor:
J. Lines, T. Corcoran, R. Sangster, E.J. Stott, Stuart J. Brown, Stephen Norley, S. MacManus, G. Davis, Neil Almond, J. Cowie, R. Hull, P. Silvera, A. Wade-Evans, A. Jenkins, Richard Stebbings, W. Elsley, M. Sethi, Deborah Ferguson, Neil Berry
Publikováno v:
Journal of Medical Primatology. 36:131-142
Background A new challenge stock of the simian immunodeficiency virus SIVmacJ5 has been produced following passage in vivo. Methods SIVmacJ5 3/92 (J5M), was passaged serially through cynomolgus macaques (Macaca fascicularis) by intravenous inoculatio
Publikováno v:
Veterinary Microbiology
A strain of bovine coronavirus (BC) adapted to tissue culture, was inoculated into organ cultures of bovine foetal trachea. Haemagglutinin in the fluid from infected organ cultures reached titres of 32 and characteristic coronavirus particles were ob
Autor:
Robin Hull, P. Silvera, K. Silvera, Neil Almond, M. Murphy-Corb, T. Corcoran, Jenny Lines, K. Kent, E.J. Stott, Barry Walker, J. Rose, Rebecca Sangster, P. Momin, C. Bruck, Paul A. Luciw
Publikováno v:
Journal of General Virology. 79:423-432
Human immunodeficiency virus type 1 (HIV-1) envelope vaccines can now be evaluated for efficacy in macaques by challenging with chimeric viruses in which the env, tat and rev genes of simian immunodeficiency virus (SIV) have been replaced by those of
Autor:
Rebecca Sangster, P. Silvera, J. Rose, Richard Stebbings, Neil Almond, Barry Walker, E.J. Stott
Publikováno v:
Journal of General Virology. 78:1919-1922
To evaluate its role in protection, immune serum was collected from four macaques which were chronically infected with live attenuated simian immunodeficiency virus (SIVmacC8) and had resisted challenge with wild-type SIVmacJ5. The immune serum was t
Autor:
K.H.G. Mills, M. Page, P. Kitchin, L. Chan, W. Jones, P. Silvera, T. Corcoran, B. Flanagan, C. Ling, C. Thiriart, M. DeWilde, C. Bruck, E. Rud, B. Clark, E.J. Stott
Publikováno v:
Journal of Medical Primatology. 22:104-109
Macaques were immunised with lentil lectin purified recombinant SIVmac (BK28) derived gp160 (rgp160) with or without live vaccinia (vac)-env (BK28) priming, followed by a final boost with solid matrix antibody antigen (SMAA)-gp160 (J5) complexes and
Autor:
Martin Cranage, A. Baskerville, Ronald C. Desrosiers, Nicola Cook, Graham Henry Farrar, T. Corcoran, L. A. E. Ashworth, Mike Dennis, Michael Murphey-Corb, E.J. Stott, P. J. Greenaway, P. Kitchin, J. Rose, Natasha Polyanskaya, B. W. McBride
Publikováno v:
AIDS Research and Human Retroviruses. 9:13-22
Inactivated, partially purified simian immunodeficiency virus (SIVmac) protected macaques from intravenous challenge with homologous and heterologous strains of SIV that had been grown on human cells but no protection against challenge with monkey pe
Autor:
K.H.G. Mills, M. Page, W.L. Chan, P. Kitchin, E.J. Stott, F. Taffs, W. Jones, J. Rose, C. Ling, P. Silvera, T. Corcoran, B. Flanagan, A. Burny, F. Bex, M. Delchambre, O. Van Opstal, L. Fabry, C. Thiriart, A. Delers, M. DeWilde, C. Bruck
Publikováno v:
Journal of Medical Primatology. 21:50-58
Vaccination of cynomolgus macaques with beta-propiolactone inactivated SIVmacBK28 in Freund's adjuvant induced low but detectable levels of anti-SIV envelope (env) antibodies and T-cell responses and protected against challenge with the 32H isolate o
Transmission Studies with Simian Immunodeficiency Virus of Macaques; Persistent Infection of Baboons
Publikováno v:
Intervirology. 34:53-61
The host range of SIVmac was investigated in three monkey species. Blood-borne and cell-adapted virus inocula obtained from a rhesus macaque infected with SIVmac251 were compared. African green monkeys were not susceptible to infection, whereas baboo
Autor:
C. Thiriart, K. Kent, G Stallard, L Gritz, Martin Cranage, E.J. Stott, C. Collignon, P. Silvera, T. Corcoran
Publikováno v:
AIDS. 5:829-836
Eighteen monoclonal antibodies (MAb) to simian immunodeficiency virus (SIV) envelope have been characterized. All MAb were shown to bind to viral antigens on the surface of unfixed SIV-infected cells and to precipitate surface glycoproteins of SIVmac