Zobrazeno 1 - 10
of 81
pro vyhledávání: '"E.J. Søderlund"'
Autor:
Vicente Rodilla, G. Brunborg, E. Dybing, Richard Wiger, Kirsti Haug, Jørn A. Holme, Jan K. Hongslo, E.J. Søderlund
Publikováno v:
Cell Biology and Toxicology. 14:267-282
We investigated 1,2-dibromo-3-chloropropane (DBCP)-induced DNA damage, cell cycle alterations and cell death in two cell lines, the human leukemia HL-60 and the pig kidney LLCPK1, both of which are derived from potential target sites for DBCP-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed0e83d93eaa926826731576924679f
https://doi.org/10.1023/a:1007482924707
https://doi.org/10.1023/a:1007482924707
Autor:
Paul G. Pearson, E.J. Søderlund, G. Brunborg, James G. Omichinski, Sidney D. Nelson, E. Dybing, Jørn A. Holme, Robert H. McClanahan
Publikováno v:
Toxicology and Applied Pharmacology. 118:196-204
Analogs of tris(2,3-dibromopropyl)phosphate (Tris-BP) either labeled at specific positions with carbon-14 and phosphorus-32 or dual-labeled with both deuterium and tritium were administered to male Wistar rats at a nephrotoxic dose of 360 mumol/kg. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda82fb02de5fb056d213225258b7537
https://doi.org/10.1006/taap.1993.1025
https://doi.org/10.1006/taap.1993.1025
Publikováno v:
Cell Biology and Toxicology. 7:413-432
1,2-Dibromo-3-chloropropane (DBCP) and a number of halogenated propane analogs induced DNA damage in rat hepatocytes in vitro measured by an automated alkaline elution method. Short-term (2 hrs) cytotoxic effects of DBCP were not observed until the D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e021802aa7b43c92e85e2b54d8b35d
https://doi.org/10.1007/bf00124075
https://doi.org/10.1007/bf00124075
The non-genotoxicity to rodents of the potent rodent bladder carcinogens o-anisidine and p-cresidine
Autor:
D. Gulati, Gunnar Brunborg, R. Shanu-Wilson, Jørn A. Holme, B. Pool-Zobel, J.P. Wojciechowski, Peter Schmezer, Helen Tinwell, E.J. Søderlund, P.A. Lefevre, John Ashby
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 250:115-133
The two potent rodent bladder carcinogens o -anisidine and p -cresidine, and the structurally related non-carcinogen 2,4-dimethoxyaniline, have been extensively evaluated for genotoxicity to rodents and found to be inactive. Most data were generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df48a0832407aaebb307be13c5e3e888
https://doi.org/10.1016/0027-5107(91)90168-n
https://doi.org/10.1016/0027-5107(91)90168-n
Autor:
A.-K. Olsen, E. Dybing, G. Brunborg, Christine Bjørge, E.J. Søderlund, Erling Seeberg, Tim Scholz, M. Trbojevic, Magnar Bjørås, Jørn A. Holme, Richard Wiger
Publikováno v:
Archives of Toxicology ISBN: 9783642468582
Several recent studies indicate declines in sperm production, as well as increases in the incidence of genitourinary abnormalities such as testicular cancer, cryptorchidism and hypospadias (Toppari et al., 1996). It is not known if these effects are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0c30498a9762d2991764f95d515d66b
https://doi.org/10.1007/978-3-642-46856-8_14
https://doi.org/10.1007/978-3-642-46856-8_14
Autor:
E. Dybing, Robert H. McClanahan, E.J. Søderlund, Paul G. Pearson, Sidney D. Nelson, James G. Omichinski
Publikováno v:
Toxicology and applied pharmacology. 118(2)
Analogs of tris(2,3-dibromopropyl)phosphate (Tris-BP) either labeled at specific positions with carbon-14, phosphorus-32, or oxygen-18 or dual-labeled with both deuterium and tritium were used as metabolic probes to study the chemical and metabolic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dfc27225cc7414ecbbd08b58a3eac2
https://pubmed.ncbi.nlm.nih.gov/8441997
https://pubmed.ncbi.nlm.nih.gov/8441997
Autor:
Rune Becher, E. Dybing, E.J. Søderlund, Jørn A. Holme, G. Brunborg, Marit Låg, Per E. Schwarze
Publikováno v:
Archives of Toxicology ISBN: 9783642772627
The many different cell types identified in the lungs show a broad variation in morphology, function and metabolic capacity. Because of this variation certain cell types are more susceptible to the toxic insult of chemical exposures. The bronchiolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118072d5e98072d8e7cf3f2bce41685d
https://doi.org/10.1007/978-3-642-77260-3_19
https://doi.org/10.1007/978-3-642-77260-3_19
Autor:
E. Dybing, J. G. Omichinski, Marit Låg, Paul G. Pearson, E.J. Søderlund, Sidney D. Nelson, Gunnar Brunborg, Jørn A. Holme
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468458794
A number of cases of infertility were discovered in 1977 among men working in a factory formulating the nematocide 1,2-dibromo-3-chloropropane (DBCP) (Whorton et al., 1977). These workers were found to have azoospermia or oligospermia. In the severel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774d886e9d62bb4d2dee23eb09adad26
https://doi.org/10.1007/978-1-4684-5877-0_63
https://doi.org/10.1007/978-1-4684-5877-0_63
Publikováno v:
Biochemistry. 29(20)
The nematocide and soil fumigant 1,2-dibromo-3-chloropropane (DBCP) is a carcinogen and a mutagen and displays target-organ toxicity to the testes and the kidney. It has been proposed that both cytochrome P-450 mediated activation and glutathione (GS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e841e174952ddba57c2bb796486636a
https://pubmed.ncbi.nlm.nih.gov/2364069
https://pubmed.ncbi.nlm.nih.gov/2364069
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 360:287-288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2293574b423820fc276edfc360b06fc0
https://doi.org/10.1016/s0165-1161(96)90183-1
https://doi.org/10.1016/s0165-1161(96)90183-1