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Autor:
E.J. Kuip, Iam Mandjes, M. Jonge-Lavrencic, CP Schroeder, M. J. Holtkamp, Inge R. H. M. Konings, Judith R. Kroep, J. P. Lotz, Ulrike Nitz, M.N. Wymenga, Anthony Gonçalves, M. Graeser, Sabine C. Linn, Margaret Schot, Agnes Jager, Valesca P. Retèl, E. E. van der Wall, S.B. Vliek, Vcg Tjan-Heijnen
Publikováno v:
Cancer Research. 78:OT2-07
Background: An intact homologous repair (HR) pathway is essential for error-free repair of DNA double strand breaks (DSB). Preclinical and clinical data have shown that breast cancer (BC) cells with a defect in the HR pathway are a target for DNA DSB