Zobrazeno 1 - 10
of 54
pro vyhledávání: '"E.I.H. van der Voort"'
Autor:
Andreea Ioan-Facsinay, E.I.H. van der Voort, T.W.J. Huizinga, R.E.M. Toes, Annemarie L. Dorjée, J. Roos, A. J. M. Schuerwegh, I. M. Bajema
Publikováno v:
Proceedings of the National Academy of Sciences. 107:2586-2591
Rheumatoid arthritis (RA) is a systemic autoimmune disease involving inflammation of the joints. Among the autoantibodies described in RA, anticitrullinated protein antibodies (ACPAs) are highly specific and predictive for RA. In addition, ACPAs have
Creation of immune ‘stealth’ genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1
Autor:
René E. M. Toes, R. Offringa, C. J. M. Melief, Martine Ossevoort, B M J Visser, Rob C. Hoeben, E.I.H. van der Voort, D J M van den Wollenberg
Publikováno v:
Gene Therapy. 10:2020-2028
A major obstacle in gene-therapy protocols is T-cell-mediated destruction of transgene-expressing cells. Therefore new approaches are needed to prevent rapid clearance of transduced cells. We exploited the Gly-Ala repeat (GAr) domain of the Epstein-B
Autor:
C. J. M. Melief, E.I.H. van der Voort, L. Diehl, René E. M. Toes, Rienk Offringa, A.T. Den Boer
Publikováno v:
Journal of Molecular Medicine. 78:363-371
CD40 and CD40 ligand (CD40L) have been implicated as important molecules for the transformation of nonactivated antigen-presenting cells (APC) into cells that are potent inducers of cytotoxic T lymphocyte (CTL) immunity. The onset of a successful imm
Autor:
René E. M. Toes, Cornelis J. M. Melief, R. Offringa, E.I.H. van der Voort, Stephen P. Schoenberger
Publikováno v:
Nature. 393:480-483
Although in vivo priming of CD8+ cytotoxic T lymphocytes (CTLs) generally requires the participation of CD4+ T-helper lymphocytes, the nature of the 'help' provided to CTLs is unknown. One widely held view is that help for CTLs is mediated by cytokin
Autor:
Twj Huizinga, Hendy Kristyanto, Priscilla F Kerkman, E.I.H. van der Voort, Dominique Baeten, Hans Scherer, Rem Toes, Hergen Spits
Publikováno v:
Annals of the Rheumatic Diseases. 75:132.2-132
Background Rheumatoid arthritis (RA) is characterized by the formation of autoantibodies against citrullinated antigens (CA). Intriguingly, depletion of CD20+ B cells leads to significant clinical improvement in the majority of patients, despite the
Autor:
Leendert A. Trouw, R.E.M. Toes, Hans Scherer, T.W.J. Huizinga, Priscilla F Kerkman, E.I.H. van der Voort
Publikováno v:
Annals of the Rheumatic Diseases, 71, A33-A33
Backgroundand objectives Anticitrullinated protein antibodies (ACPA) show high specificity for rheumatoid arthritis (RA) and predict disease onset and severity. Several lines of research indicate that ACPA are pathogenetically involved in disease dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8f1efcd1cf6b41e2331ede1b24b575
http://hdl.handle.net/1887/100456
http://hdl.handle.net/1887/100456
Autor:
E W N Levarth, L Damjanovska, A.H.M. van der Helm-van Mil, E.I.H. van der Voort, T.W.J. Huizinga, Gerrie Stoeken-Rijsbergen, René E. M. Toes, Mohamed M Thabet
Publikováno v:
Annals of the Rheumatic Diseases; Vol 69
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 69(4), 730-732
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 69(4), 730-732
Objectives To evaluates the diagnostic performance of the anti-CCP2, anti-CCP3 and anti-mutated citrullinated vimentin (anti-MCV) tests in differentiating rheumatoid arthritis (RA) from other forms of arthritis in a clinical setting of early arthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d1c996c27f44fda17d5fa78dedac96
https://hdl.handle.net/1887/109011
https://hdl.handle.net/1887/109011
Autor:
Martine J. Jager, Roger P. M. Sutmuller, C. J. M. Melief, René E. M. Toes, LM van Duivenvoorde, R. Offringa, Lucas R. H. M. Schurmans, E.I.H. van der Voort, John A. Tine
Publikováno v:
Journal of immunology (Baltimore, Md., 165(12), 7308-7315. American Association of Immunologists
HLA-A*0201-restricted CTL against human gp100 were isolated from HLA-A*0201/Kb (A2/Kb)-transgenic mice immunized with recombinant canarypox virus (ALVAC-gp100). These CTL strongly responded to the gp100154–162 epitope, in the context of both the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c82a13d9c5560a7c3d47487bb3a47e
https://pure.amc.nl/en/publications/adoptive-t-cell-immunotherapy-of-human-uveal-melanoma-targeting-gp100(97ff51e5-fa13-4ada-a78b-13e9bca73573).html
https://pure.amc.nl/en/publications/adoptive-t-cell-immunotherapy-of-human-uveal-melanoma-targeting-gp100(97ff51e5-fa13-4ada-a78b-13e9bca73573).html
Autor:
Leendert A. Trouw, Rem Toes, Twj Huizinga, Priscilla F Kerkman, E.I.H. van der Voort, Hans Scherer
Publikováno v:
Annals of the Rheumatic Diseases. 71:312.2-312
Background Anti-citrullinated protein antibodies (ACPA) are among the most important molecular candidates that could drive the inflammatory immune response in a subset of patients with rheumatoid arthritis (RA). Although many aspects of the ACPA immu
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.