Zobrazeno 1 - 10
of 31
pro vyhledávání: '"E.I. Krajnc"'
Publikováno v:
International Journal of Immunopharmacology. 17:535-543
Drug addicts are prone to infection with viruses including hepatitis-B and HIV. Besides indirect effects as a consequence of lifestyle, heroin and methadone may also enhance the risk of infections by a direct immunotoxic effect affecting resistance.
Publikováno v:
Toxicology and Applied Pharmacology. 102:21-33
The respiratory tract is a major route of exposure to noxious agents as well as pathogens such as viruses. Natural killer (NK) activity is an important first line of defense to virally infected cells as well as certain neoplasms; therefore, testing t
Autor:
E.I. Krajnc, P.W. Helleman, H.A.M.G. Vaessen, C.A. van der Heijden, J.G. Loeber, F.X.R. van Leeuwen, P.W. Wester
Publikováno v:
Food and Chemical Toxicology. 28:179-196
In a 106-wk toxicity and carcinogenicity study, groups of 60 male and 60 female weanling Wistar rats were fed 0, 0.5, or 50 mg bis(tri-n-butyltin)oxide (TBTO)/kg diet. In males, feed consumption was increased in all treated groups and increased water
Publikováno v:
Aquatic Toxicology. 16:53-72
Toxicity studies were carried out on the Japanese medaka (Oryzias latipes) with bis(tri-n-butyltin)oxide (TBTO) and di-n-butyltindichloride (DBTC), with emphasis on histopathological effects. Freshly fertilized eggs were exposed for 1 and 3 months to
Publikováno v:
Toxicology letters. 151(1)
Hormonal steroids have a widespread use in medicine and their side effects are continuously debated. The possible genotoxic activity of steroids has been the subject of many investigations. The natural estrogens estradiol, estrone and estriol are gen
Publikováno v:
Toxicology and applied pharmacology. 105(1)
To investigate whether immune function suppression observed in an earlier study after short-term bis(tri-n-butyltin)oxide (TBTO) exposure also occurred after long-term treatment, function studies for specific and nonspecific resistance were performed
Publikováno v:
Toxicology and Applied Pharmacology. 75:387-408
To evaluate the functional significance of bis(tri-n-butyltin)oxide (TBTO)-induced thymus atrophy, lymphocyte depletion in spleen and lymph nodes, lymphopenia, and increased serum IgM and decreased IgG concentrations, in vivo and in vitro function st
Publikováno v:
Food and Chemical Toxicology. 20:311-314
Eight cobalt compounds were administered to rats by gastric intubation, and the following LD 50 values (in mg anhydrous compound/kg body weight) were determined: cobalt(II) fluoride 150, cobalt(II) oxide 202, cobalt(II) phosphate 387, cobalt(II) brom
Publikováno v:
Human Toxicology. 3:7-21
1 Urine was collected from 289 inhabitants of a cadmium-polluted quarter of Stadskanaal. The excretion of cadmium, protein, beta-2-microglobulin and glucose were determined. After being divided according to sex and to smoking habits, the results of t
Publikováno v:
Human Toxicology. 1:393-402
1 Bromide, 1 mg kg-1 daily, was administered to 21 healthy volunteers (11 females not using oral contraceptives and not pregnant and 10 males, during 8 weeks or 2 full cycles to determine whether ingestion of a dose equal to the acceptable daily inta