Zobrazeno 1 - 10
of 45
pro vyhledávání: '"E.David Saggerson"'
Publikováno v:
European Journal of Biochemistry. 271:954-961
Recent studies have suggested that parts of the hepatic activities of diacylglycerol acyltransferase and acyl cholesterol acyltransferase are expressed in the lumen of the endoplasmic reticulum (ER). However the ER membrane is impermeable to the long
Autor:
N. M. Broadway, E.David Saggerson, Nigel Turner, Richard J. Pease, Graeme M. Birdsey, Majid Shayeghi
Publikováno v:
Biochemical Journal. 370:223-231
Liver microsomal fractions contain a malonyl-CoA-inhibitable carnitine acyltransferase (CAT) activity. It has been proposed [Fraser, Corstorphine, Price and Zammit (1999) FEBS Lett. 446, 69—74] that this microsomal CAT activity is due to the liver
Publikováno v:
International Journal of Developmental Neuroscience. 14:701-705
The effect of GTP concentration on forskolin-stimulated adenylyl cyclase activity was examined in synaptosomal membranes from 15-day-old rats that were hypothyroid due to administration of propylthiouracil and a low-iodine diet to the mothers during
Publikováno v:
European Journal of Biochemistry. 229:741-748
The provision of a diet high in saturated and monounsaturated fat for 28 days evoked a significant (1.9-fold) increase in pyruvate-dehydrogenase kinase activity measured in isolated mitochondria from representative slow-twitch (oxidative) skeletal mu
Autor:
John R.D. Mitchell, E.David Saggerson
Publikováno v:
International Journal of Biochemistry. 26:181-187
1. Glycerolphosphate acyltransferase (GPAT) was solubilized from the rat liver mitochondrial membranes using sodium cholate. Dithiothreitol was necessary to stabilize the solubilized enzyme on storage. 2. Unlike the enzyme in situ in mitochondrial me
Autor:
E.David Saggerson, John R.D. Mitchell
Publikováno v:
International Journal of Biochemistry. 26:67-72
1. Exposure to cold has previously been shown to considerably increase the activity of the mitochondrial form of glycerolphosphate acyltransferase (GPAT) in brown adipose tissue (A. C. Darnley, C. A. Carpenter and E. D Saggerson, Biochem. J. 253, 351
Autor:
E.David Saggerson, N. M. Broadway
Publikováno v:
FEBS Letters. 371:137-139
The sulphonylureas glibenclamide and tolbutamide inhibited carnitine acyltransferase activities in rat liver microsomes. Glibenclamide was a more potent inhibitor than tolbutamide. The effect of tolbutamide on the malonyl-CoA-inhibitable transferase
Publikováno v:
Current Views of Fatty Acid Oxidation and Ketogenesis ISBN: 9780306462009
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a85cdd1bc0f73b0ea2a7abb66db63b9a
https://doi.org/10.1007/0-306-46818-2_6
https://doi.org/10.1007/0-306-46818-2_6
Autor:
Michael Orford, E.David Saggerson
Publikováno v:
Journal of neurochemistry. 67(2)
A readily soluble 5'-nucleotidase was purified 1,800-fold from rat brain 105,000-g supernatant. The enzyme showed similarity to the 5'-nucleotidase ectoenzyme of plasma membranes. It exhibited a low Km for AMP, which was preferred over IMP as substra
Publikováno v:
FEBS letters. 311(3)
Hypoglycaemia is a major complication of severe malaria [(1990) Trans. Roy. Soc. Trop. Med. 84 (suppl. 2) 1–65], especially cerebral malaria, in which it is associated with increased mortality [(1990) Lancet 336, 1039–1043; (1989) Quart. J. Med.