Zobrazeno 1 - 10 of 60 pro vyhledávání: '"E.D. Kuhlmann"'
1
Plasticity revealed by transcranial magnetic stimulation of early visual cortex
Autor: A.H.M. van Vugt, B. P. M. Janssen, E.D. Kuhlmann, C.A.G.G. Driessen, August F. Deutman, J.J.M. Janssen, H.J. Winkens
Publikováno v: NeuroReport. 11:1565-1569
The effect of retinoic acid on the differentiation of a human retinal pigment epithelium-derived cell line ARPE-19 was studied. Differentiation of ARPE-19 cells is delayed by retinoic acid. The minimum all-trans-retinoic acid concentration needed for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a627dd83747bc245fd59ebf308aa2c06
https://doi.org/10.1097/00001756-200005150-00040
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2
Retinoic acid receptors and retinoid X receptors in the mature retina: Subtype determination and cellular distribution
Autor: H.J. Winkens, C.A.G.G. Driessen, August F. Deutman, A.P.M. Janssen, A.H.M. van Vugt, J.J.M. Janssen, E.D. Kuhlmann
Publikováno v: Current Eye Research, 19, pp. 338-347
Current Eye Research, 19, 338-347
In the mature retina retinoic acid (RA) biosynthesis was reported to be regulated by light. RA is of vital importance for proper function of the retina. RA activity is mediated by interaction with nuclear retinoic acid receptors (RARs) and retinoid X
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bd5745477fdb40dc0c9e0f6148d99f
https://doi.org/10.1076/ceyr.19.4.338.5307
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3
Experimental Autoimmune Anterior Uveitis (EAAU). III. Induction by Immunization with Purified Uveal and Skin Melanins
Autor: H.J. Winkens, E.D. Kuhlmann, R.M. Broekhuyse
Publikováno v: Experimental Eye Research. 56:575-583
The pathogenicity of uveal tissue and melanin has been a controversial subject for a long time. The present new approach has elucidated some of the problems. Melanin granules have been extracted from bovine choroid, iris, hair and skin, and from huma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e94599f8f75a8464970dd5d68b3ea4
https://doi.org/10.1006/exer.1993.1071
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4
Experimental autoimmune posterior uveitis accompanied by epitheloid cell accumulations (EAPU). A new type of experimental ocular disease induced by immunization with PEP-65, a pigment epithelial polypeptide preparation
Autor: E.D. Kuhlmann, H.J. Winkens, R.M. Broekhuyse
Publikováno v: Experimental Eye Research. 55:819-829
Purified retinal pigment epithelial cells of bovine eyes have been fractionated by a series of buffer and detergent extractions. The electropherogram of the buffer-insoluble, Triton X-100-soluble fraction (RPE-TS) exhibits a major polypeptide band of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e060d45e93f3532629bc153ca467a5c
https://doi.org/10.1016/0014-4835(92)90008-g
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5
Experimental autoimmune anterior uveitis (EAAU). II. Dose-dependent induction and adoptive transfer using a melanin-bound antigen of the retinal pigment epithelium
Autor: R.M. Broekhuyse, H.J. Winkens, E.D. Kuhlmann
Publikováno v: Experimental Eye Research. 55:401-411
Retinal pigment epithelial cell fractions have been investigated for their capacity to induce experimental uveitis. Cells of the dark (melanotic) and light areas of the bovine RPE have subsequently been extracted by buffer, Triton X-100, sodium dodec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec4070313247131feba3bc3ac32f53e
https://doi.org/10.1016/0014-4835(92)90112-6
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6
Experimental autoimmune anterior uveitis (EAAU), a new form of experimental uveitis. I. Induction by a detergent-insoluble, intrinsic protein fraction of the retinal pigment epithelium
Autor: H.J. Winkens, R.M. Broekhuyse, A.H.M. van Vugt, E.D. Kuhlmann
Publikováno v: Experimental Eye Research. 52:465-474
The uveitogenicity of several protein fractions of the bovine retinal pigment epithelium (RPE) was studied in Lewis rats, and a major pathogenic fraction was selected. Fresh RPE cells were carefully isolated and purified in order to minimize the pres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194af571b496034e497b036f98f70873
https://doi.org/10.1016/0014-4835(91)90044-f
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7
Uveitogenic 28/30 kD and 43 kD polypeptides in pigment epithelial membranes of the retina
Autor: R.M. Broekhuyse, E.D. Kuhlmann
Publikováno v: Ocular Immunology and Inflammation, 5, 19-26. Aeolus press
Ocular Immunology and Inflammation, 5, pp. 19-26
Ocular Immunology and Inflammation, 5, 19-26
Ocular Immunology and Inflammation, 5, 1, pp. 19-26
The purpose of this study was the search for new intrinsic polypeptides of the retinal pigment epithelium (RPE) capable of evoking experimental uveitis. A membrane fraction was prepared from purified bovine RPE cells. The Triton X-100 soluble protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc6a510daceb4c4bcef500b11c59dc3
https://pubmed.ncbi.nlm.nih.gov/9145689
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8
Differential effect of macrophage depletion on two forms of experimental uveitis evoked by pigment epithelial membrane protein (EAPU), and by melanin-protein (EMIU)
Autor: R.M. Broekhuyse, E.D. Kuhlmann, H.J. Winkens, N. van Rooijen, I. Huitinga
Publikováno v: Experimental Eye Research, 65, 841-848. Academic press ltd
Experimental Eye Research, 65, 841-848. Academic Press Inc.
Experimental Eye Research, 65, 6, pp. 841-848
Experimental Eye Research, 65, 841-848
Broekhuyse, R M, Huitinga, I, Kuhlmann, E D, van Rooyen, N & Winkens, H J 1997, ' Differential effect of macrophage depletion on two forms of experimental uveitis evoked by pigment epithelial membrane protein (EAPU), and by melaninprotein (EMIU) ', Experimental Eye Research, vol. 65, pp. 841-848 . https://doi.org/10.1006/exer.1997.0396
Experimental Eye Research, 65, pp. 841-848
The purpose of the present study was to clinically and histologically investigate the influence of macrophage depletion on the development of experimental autoimmune pigment epithelial membrane protein-induced uveitis (EAPU), and experimental melanin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089aac348a99e5a3e65b587bbc6a58d2
http://hdl.handle.net/2066/28983
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9
Macrophage subpopulations and RPE elimination in the pathogenesis of experimental autoimmune pigment epithelial protein-induced uveitis (EAPU)
Autor: E.D. Kuhlmann, R.M. Broekhuyse, Theo A. Peters, Wim Kuijpers
Publikováno v: Experimental Eye Research, 62, pp. 471-479
Experimental Eye Research, 62, 471-479
Experimental Eye Research, 62, 471-479. Academic press ltd
Experimental Eye Research, 62, 5, pp. 471-479
Experimental autoimmune pigment epithelial protein-induced uveitis (EAPU) is a new type of disease that destroys the retinal pigment epithelium (RPE), and exhibits a hitherto unknown form of progressive chorioretinal dystrophy in which neuroretinal i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d15fdf255743fb9f3105ad735c33dc
https://hdl.handle.net/2066/223105
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10
Intraperitoneally injected melanin is highly uveitogenic
Autor: E.D. Kuhlmann, R.M. Broekhuyse, H.J. Winkens
Publikováno v: Experimental Eye Research, 62, pp. 199-200
Experimental Eye Research, 62, 199-200
Experimental Eye Research, 62, 2, pp. 199-200
Experimental Eye Research, 62, 199-200. Academic press ltd
Contains fulltext : 24166___.PDF (Publisher’s version ) (Open Access)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76e16d2d14f28a800aa56b41c8f0224
https://hdl.handle.net/2066/223086
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