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pro vyhledávání: '"E.B. Cook"'
Akademický článek
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Akademický článek
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Autor:
T. Norman Palmer, Victor R. Preedy, George E. Griffin, Tim J Peters, Derek C. Macallan, E.B. Cook
Publikováno v:
Alcohol. 14:545-549
An investigation was carried out to determine changes in the contents of skeletal muscle myofibrillary proteins (i.e., the contractile fraction composed principally of actin and myosin) and gene expression in skeletal muscle in response to ethanol fe
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1180:207-214
Chronic ethanol feeding in the rat is associated with a skeletal myopathy involving primarily type-II muscle fibers, which is recognised to be mediated via a specific impairment in protein turnover. This paper investigates whether the cause of this m
Akademický článek
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Autor:
A. Chan, Larry Lowe, Roy Chen, Jerry Wilson, E.B. Cook, Edward L. Morgan, Frank M. Graziano, Rudi Varro, N.P. Barney, J.L. Stahl
Publikováno v:
Journal of immunological methods. 254(1-2)
Tears play an essential role in maintaining corneal and conjunctival integrity by providing a tightly regulated, optimal extracellular environment critical to its numerous functions, which include anti-microbial defense, wound healing and inflammator
Publikováno v:
The international journal of biochemistrycell biology. 28(5)
Sepsis is associated with net breakdown of skeletal muscle protein, mediated partly by reduced rates of muscle protein synthesis. This study investigated the role of altered gene expression for specific muscle proteins in mediating reduced protein sy
Publikováno v:
Alcohol and Alcoholism.
This study was carried out in an attempt to differentiate between the contribution of liver impairment and direct actions of alcohol in myopathy of alcoholic liver disease. Using an animal model of cirrhosis we have previously shown that protein synt
Autor:
E.B. Cook, Victor R. Preedy, Derek C. Macallan, Tim J Peters, Norman T Palmer, George E. Griffin
Publikováno v:
Europe PubMed Central
Chronic ethanol misuse causes an impairment of skeletal muscle function, with selective reductions in the diameter of Type I1 (anaerobic glycolytic, fast twitch) fibres whilst Type I (aerobic oxidative, slow twitch) fibres are relatively protected [I
Publikováno v:
Alcohol and Alcoholism.
We investigated the use of a microprocessor-controlled laser-Doppler monitor to measure blood-flow in unanaesthetised animals. The apparatus permitted real-time assessment of cutaneous blood-flow, identified artifactual changes due to limb and body m