Zobrazeno 1 - 10
of 28
pro vyhledávání: '"E.-R. Sailer"'
Autor:
M. Schabet, Hasan Safayhi, Stephan Winter, Hermann P. T. Ammon, E.-R. Sailer, Peter Groscurth, Michael Weller, Tamara Glaser
Publikováno v:
British Journal of Cancer
Steroids are essential for the control of oedema in human malignant glioma patients but may interfere with the efficacy of chemotherapy. Boswellic acids are phytotherapeutic anti-inflammatory agents that may be alternative drugs to corticosteroids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fd2f1fd795e937ca1dd49c5046677a
https://doi.org/10.1038/sj.bjc.6690419
https://doi.org/10.1038/sj.bjc.6690419
Autor:
R. F. Hoernlein, Lakshminarayanapuram R. Subramanian, E.-R. Sailer, Hasan Safayhi, Beatrice Rall, Hermann P. T. Ammon
Publikováno v:
British Journal of Pharmacology. 117:615-618
1. 5-Lipoxygenase (5-LOX) products from endogenous arachidonic acid in ionophore-stimulated peritoneal polymorphonuclear leukocytes (PMNL) and from exogenous substrate (20 microM) in 105,000 g supernatants were measured. 2. The effects of natural pen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274cbe53128cf29d3e4d72a9af5c7164
https://doi.org/10.1111/j.1476-5381.1996.tb15235.x
https://doi.org/10.1111/j.1476-5381.1996.tb15235.x
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 3(1)
Acetyl-11-keto-β-boswellic acid (AKAB) from Boswellia serrata and B. carterii acts directly on purified 5-lipoxygenase of human blood leukocytes at a selective site for pentacyclic triterpenes that is different from the arachidonate substrate bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea64f356a8ec0d2d2ff0557a4b6c378
https://pubmed.ncbi.nlm.nih.gov/23194864
https://pubmed.ncbi.nlm.nih.gov/23194864
Publikováno v:
Planta Medica. 60:410-413
Matricine and its transformation product chamazulene are constituents of chamomile extracts. Both have been demonstrated to exert anti-inflammatory activity in vivo. Since preparations from chamomile are used for the treatment of inflammatory skin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebe10c45d5a4a57e236bd533e539aa6
https://doi.org/10.1055/s-2006-959520
https://doi.org/10.1055/s-2006-959520
Publikováno v:
ChemInform. 27
AKBA (acetyl-11-keto-β-boswellic acid, 1) and KBA (11-keto-β-BA, 2) from Boswellia serrata Roxb. and Boswellia carterii Birdw. are direct, nonredox-type inhibitors of 5-lipoxygenase, the key enzyme for leukotriene biosynthesis (IC50 = 1.5 and 3μM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a2648052ec93ff9da2579919abb9d6
https://doi.org/10.1002/chin.199619223
https://doi.org/10.1002/chin.199619223
Publikováno v:
Archiv der Pharmazie. 329:54-56
AKBA (acetyl-11-keto-β-boswellic acid, 1) and KBA (11-keto-β-BA, 2) from Boswellia serrata Roxb. and Boswellia carterii Birdw. are direct, nonredox-type inhibitors of 5-lipoxygenase, the key enzyme for leukotriene biosynthesis (IC50 = 1.5 and 3μM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e895584edbe176b7533ebc148571209
https://doi.org/10.1002/ardp.19963290110
https://doi.org/10.1002/ardp.19963290110
Autor:
R F, Hoernlein, T, Orlikowsky, C, Zehrer, D, Niethammer, E R, Sailer, T, Simmet, G E, Dannecker, H P, Ammon
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(2)
Antiproliferative action of different pentacyclic triterpenes has repeatedly been reported, and some lipoxygenase inhibitors have been shown to induce cell death in various cell systems. Acetyl-11-keto-beta-boswellic acid (AKBA) is a pentacyclic trit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e3903691e27fc1d24731cba10f106d6
https://pubmed.ncbi.nlm.nih.gov/9918566
https://pubmed.ncbi.nlm.nih.gov/9918566
Publikováno v:
European journal of biochemistry. 256(2)
AKBA (acetyl-11-keto-beta-boswellic acid), a natural pentacyclic triterpene, is an orally active leukotriene-synthesis inhibitor, which acts by a 5-lipoxygenase-directed, non-redox, non-competitive mechanism. It is the only leukotriene-synthesis inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ba925a98ff8ae1a699017de592190
https://pubmed.ncbi.nlm.nih.gov/9760176
https://pubmed.ncbi.nlm.nih.gov/9760176
Autor:
E.-R. Sailer, Hasan Safayhi
Publikováno v:
Planta medica. 63(6)
Pentacyclic triterpenes (PTs) as aglycones of saponins have a wide distribution in plants, and many of them have been used as anti-inflammatory remedies in folk medicine. This survey critically reviews the effects of PTs on proinflammatory mediator s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db2a0e25110692a52b77e8e396bf239
https://pubmed.ncbi.nlm.nih.gov/9434597
https://pubmed.ncbi.nlm.nih.gov/9434597
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
Frankincense extracts and boswellic acids, biologically active pentacyclic triterpenes of frankincense, block leukotriene biosynthesis and exert potent anti-inflammatory effects. Screening for additional effects of boswellic acids on further proinfla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea7cd16f554c331fd4f7c9c2bf025036
https://pubmed.ncbi.nlm.nih.gov/9103531
https://pubmed.ncbi.nlm.nih.gov/9103531