Zobrazeno 1 - 10
of 485
pro vyhledávání: '"E.-J Speckmann"'
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 2, Pp 371-379 (2004)
Editing and alternative splicing of mRNA are posttranscriptional steps probably involved in pathophysiological aspects of epilepsy. The present study analyses the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit GluR2 with re
Externí odkaz:
https://doaj.org/article/c16b0be72a4a40d4bf7bec79a3fab740
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 1, Pp 70-79 (2004)
Cortical spreading depression (CSD) has been suggested to underlie some neurological disorders such as migraine. Despite the intensity with which many investigators have studied SD in the brain, only a few studies have aimed to identify SD in the spi
Externí odkaz:
https://doaj.org/article/ed1e114bd18d4cd9968b7fc4adbcae3c
Autor:
Uta Karacaoğlan, E.-J. Speckmann
Publikováno v:
Jahrbuch der Psychoanalyse. 63:181-205
Grenzflächen verbinden Räume, die gleichzeitig unterschiedlich und genügend ähnlich sein müssen. Dabei steuern sie Quantität sowie Qualität eines über sie stattfindenden Austauschs. Grenzflächen sind in den Dimensionen des Raums und der Zeit
Akademický článek
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Autor:
Christian M. Cremer, Hans-Jürgen Bidmon, Axel Schleicher, Nicola Palomero-Gallagher, Karl Zilles, E.-J. Speckmann
Publikováno v:
Neuroscience. 163:490-499
Pentylenetetrazole (PTZ) is a convulsant used to model epileptic seizures in rats. In the PTZ-model, altered heat shock protein 27 (HSP-27) expression highlights seizure-affected astrocytes, which play an important role in glutamate and GABA metaboli
Autor:
Heidrun Straub, E.-J. Speckmann, Alois Ebner, Ingrid Tuxhorn, M. Schwarz, E. Siep, H. Pannek, C. Rüschenschmidt, Rüdiger Köhling, Ali Gorji, Peter Wolf
Publikováno v:
Journal of Neuroscience Research. 75:807-816
A-type currents powerfully modulate discharge behavior and have been described in a large number of different species and cell types. However, data on A-type currents in human brain tissue are scarce. Here we have examined the properties of a fast tr
Autor:
Heidrun Straub, Rüdiger Köhling, Uwe-Robert Koch, Georg Hagemann, E.-J. Speckmann, Christoph Redecker
Publikováno v:
Brain Research. 975:129-134
Spreading depression (SD) is characterized by a transient breakdown of neuronal function concomitant with a massive failure of ion homeostasis. It is a phenomenon that can be induced in neocortical tissue by raising excitability, e.g. injection of K(
Publikováno v:
Brain Research. 959:149-159
Intra- and extracellular recording techniques were used to study the epileptiform activity generated by guinea pig hippocampal slices perfused with free-magnesium artificial cerebrospinal fluid in the presence of physiologic (4 mM), reduced (2 mM) or
Publikováno v:
Epilepsia. 43:1455-1461
Summary: Purpose: The antiepileptic drug vigabatrin (VGB) increases intracellular availability of the inhibitory transmitter γ-aminobutyric acid (GABA) by inhibition of GABA-transaminase. A blockade of the GABA uptake is the main mechanism of action