Zobrazeno 1 - 10
of 1 646
pro vyhledávání: '"E. de Visser"'
Autor:
Olga S. Blomberg, Kevin Kos, Lorenzo Spagnuolo, Olga I. Isaeva, Hannah Garner, Max D. Wellenstein, Noor Bakker, Danique E.M. Duits, Kelly Kersten, Sjoerd Klarenbeek, Cheei-Sing Hau, Daphne Kaldenbach, Elisabeth A.M. Raeven, Kim Vrijland, Marleen Kok, Karin E. de Visser
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTThe clinical successes of immune checkpoint blockade (ICB) in advanced cancer patients have recently spurred the clinical implementation of ICB in the neoadjuvant and perioperative setting. However, how neoadjuvant ICB therapy affects the sys
Externí odkaz:
https://doaj.org/article/b656e036ddb5458b8a3bb50ca339a61b
Autor:
Dario Zimmerli, Chiara S. Brambillasca, Francien Talens, Jinhyuk Bhin, Renske Linstra, Lou Romanens, Arkajyoti Bhattacharya, Stacey E. P. Joosten, Ana Moises Da Silva, Nuno Padrao, Max D. Wellenstein, Kelly Kersten, Mart de Boo, Maurits Roorda, Linda Henneman, Roebi de Bruijn, Stefano Annunziato, Eline van der Burg, Anne Paulien Drenth, Catrin Lutz, Theresa Endres, Marieke van de Ven, Martin Eilers, Lodewyk Wessels, Karin E. de Visser, Wilbert Zwart, Rudolf S. N. Fehrmann, Marcel A. T. M. van Vugt, Jos Jonkers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Tripe-negative breast cancers poorly respond to immune checkpoint inhibition therapy, due to their immune-hostile tumour microenvironment. Authors here show that the oncogene MYC plays a pivotal role in suppressing anti-tumour immunity via directly r
Externí odkaz:
https://doaj.org/article/07f7321be51a4bf993332239abb08b2b
Autor:
Kevin Kos, Camilla Salvagno, Max D. Wellenstein, Muhammad A. Aslam, Denize A. Meijer, Cheei-Sing Hau, Kim Vrijland, Daphne Kaldenbach, Elisabeth A.M. Raeven, Martina Schmittnaegel, Carola H. Ries, Karin E. de Visser
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
While regulatory T cells (Tregs) and macrophages have been recognized as key orchestrators of cancer-associated immunosuppression, their cellular crosstalk within tumors has been poorly characterized. Here, using spontaneous models for breast cancer,
Externí odkaz:
https://doaj.org/article/6e040c8634824418819d91cace555fe4
Autor:
Wietske Pieters, Floor Hugenholtz, Kevin Kos, Maxime Cammeraat, Teddy C. Moliej, Daphne Kaldenbach, Sjoerd Klarenbeek, Mark Davids, Lisa Drost, Charlotte de Konink, Elly Delzenne-Goette, Karin E. de Visser, Hein te Riele
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiota strongly impacts the development of sporadic colorectal cancer (CRC), but it is largely unknown how the microbiota affects the pathogenesis of mismatch-repair-deficient CRC in the context of Lynch syndrome. In a mouse model for Lyn
Externí odkaz:
https://doaj.org/article/ea7cde7a89e14a07858878eb822c53b1
Autor:
Stefan Prekovic, Karianne Schuurman, Isabel Mayayo-Peralta, Anna G. Manjón, Mark Buijs, Selçuk Yavuz, Max D. Wellenstein, Alejandro Barrera, Kim Monkhorst, Anne Huber, Ben Morris, Cor Lieftink, Theofilos Chalkiadakis, Ferhat Alkan, Joana Silva, Balázs Győrffy, Liesbeth Hoekman, Bram van den Broek, Hans Teunissen, Donna O. Debets, Tesa Severson, Jos Jonkers, Timothy Reddy, Karin E. de Visser, William Faller, Roderick Beijersbergen, Maarten Altelaar, Elzo de Wit, Rene Medema, Wilbert Zwart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Glucocorticoids (GC) are reported to block cancer cell proliferation, but the mode of action is unclear. Here the authors show that glucocorticoid receptor activation induces cancer cell dormancy in lung cancer by regulating CDKN1C expression through
Externí odkaz:
https://doaj.org/article/e4c712e9c2534821b3dbea828efb9470
Autor:
Stijn J. H. Waaijer, Frans V. Suurs, Cheei-Sing Hau, Kim Vrijland, Karin E. de Visser, Derk Jan A. de Groot, Elisabeth G. E. de Vries, Marjolijn N. Lub-de Hooge, Carolina P. Schröder
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Macrophages can promote tumor development. Preclinically, targeting macrophages by colony-stimulating factor 1 (CSF1)/CSF1 receptor (CSF1R) monoclonal antibodies (mAbs) enhances conventional therapeutics in combination treatments. The physiological d
Externí odkaz:
https://doaj.org/article/8ac7559f52274598852b4ce0df5c1d1f
Autor:
Danique E. M. Duits, Camilla Salvagno, Elisabeth A. M. Raeven, Kim Vrijland, Marjolein C. Stip, Cheei-Sing Hau, Daphne Kaldenbach, Karin E. de Visser
Publikováno v:
Cells, Vol 11, Iss 15, p 2346 (2022)
Neutrophils are not only crucial immune cells for the neutralization of pathogens during infections, but they are also key players in tissue repair and cancer. Several methods are available to investigate the in vivo role of neutrophils in these cond
Externí odkaz:
https://doaj.org/article/4f27d7a7921c46bbb9b2715cbd0abfde
Autor:
Leonie Voorwerk, Olga I. Isaeva, Hugo M. Horlings, Sara Balduzzi, Maksim Chelushkin, Noor A. M. Bakker, Elisa Champanhet, Hannah Garner, Karolina Sikorska, Claudette E. Loo, Inge Kemper, Ingrid A. M. Mandjes, Michiel de Maaker, Jasper J. L. van Geel, Jorianne Boers, Maaike de Boer, Roberto Salgado, Marloes G. J. van Dongen, Gabe S. Sonke, Karin E. de Visser, Ton N. Schumacher, Christian U. Blank, Lodewyk F. A. Wessels, Agnes Jager, Vivianne C. G. Tjan-Heijnen, Carolien P. Schröder, Sabine C. Linn, Marleen Kok
Publikováno v:
Nature Cancer, 4, 535-549. Springer Nature
Nature Cancer, 4(4), 535-549. Nature Research
Nature Cancer, 4(4), 535-549. Nature Research
Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research revealed an immune-related ILC subset, and in mouse ILC models, synergy between immune chec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173e4cc0d70da59f93de91b9372cee78
https://doi.org/10.1038/s43018-023-00542-x
https://doi.org/10.1038/s43018-023-00542-x
Autor:
Karin E. de Visser, Johanna A. Joyce
Publikováno v:
Cancer Cell. 41:374-403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44d6debd7a3897ace48539ac9b46fe6
https://doi.org/10.1016/j.ccell.2023.02.016
https://doi.org/10.1016/j.ccell.2023.02.016
Publikováno v:
Nature Reviews Cancer. 23:193-215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efdea0e6e4afb97e1179e2a51779760d
https://doi.org/10.1038/s41568-022-00544-4
https://doi.org/10.1038/s41568-022-00544-4