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Akademický článek

ICONIC study—conservative versus conventional oxygenation targets in intensive care patients: study protocol for a randomized clinical trial

Autor: C. C. A. Grim, L. I. van der Wal, H. J. F. Helmerhorst, D. J. van Westerloo, P. Pelosi, M. J. Schultz, E. de Jonge, for the ICONIC Investigators and PROVE Network

Publikováno v: Trials, Vol 23, Iss 1, Pp 1-12 (2022)

Abstract Background Oxygen therapy is a widely used intervention in acutely ill patients in the intensive care unit (ICU). It is established that not only hypoxia, but also prolonged hyperoxia is associated with poor patient-centered outcomes. Nevert

Externí odkaz: https://doaj.org/article/87500962dd204a13a27922612c606228

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Akademický článek

P652: MEASURING MINIMAL RESIDUAL DISEASE BEYOND 10-4 THROUGH IGHV LEADER-BASED NEXT GENERATION SEQUENCING IMPROVES PROGNOSTIC STRATIFICATION IN CHRONIC LYMPHOCYTIC LEUKEMIA

Autor: P. Hengeveld, M. van der Klift, P. M. Kolijn, F. Davi, F. Kavelaars, E. de Jonge, S. Robrecht, J. Assmann, L. van der Straten, M. Ritgen, P. Westerweel, K. Fischer, V. Goede, M. Hallek, M.-D. Levin, A. Langerak

Publikováno v: HemaSphere, Vol 6, Pp 550-551 (2022)

Externí odkaz: https://doaj.org/article/8ec2e1f167de46c895017e0b7885b87e

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Akademický článek

The effect of ICU-tailored drug-drug interaction alerts on medication prescribing and monitoring: protocol for a cluster randomized stepped-wedge trial

Autor: T. Bakker, J. E. Klopotowska, S. Eslami, D. W. de Lange, R. van Marum, H. van der Sijs, E. de Jonge, D. A. Dongelmans, N. F. de Keizer, A. Abu-Hanna

Publikováno v: BMC Medical Informatics and Decision Making, Vol 19, Iss 1, Pp 1-10 (2019)

Abstract Background Drug-drug interactions (DDIs) can cause patient harm. Between 46 and 90% of patients admitted to the Intensive Care Unit (ICU) are exposed to potential DDIs (pDDIs). This rate is twice as high as patients on general wards. Clinica

Externí odkaz: https://doaj.org/article/84f615f1c9f94f9baac601f89162e325

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Akademický článek

Carriage of antibiotic-resistant Gram-negative bacteria after discontinuation of selective decontamination of the digestive tract (SDD) or selective oropharyngeal decontamination (SOD)

Autor: E. de Jonge, R. B. P. de Wilde, N. P. Juffermans, E. A. N. Oostdijk, A. T. Bernards, E. H. R. van Essen, E. J. Kuijper, C. E. Visser, J. Kesecioglu, M. J. M. Bonten

Publikováno v: Critical Care, Vol 22, Iss 1, Pp 1-10 (2018)

Abstract Background Selective decontamination of the digestive tract (SDD) and selective oropharyngeal decontamination (SOD) reduce colonization with antibiotic-resistant Gram-negative bacteria (ARGNB), incidence of nosocomial infections and improve

Externí odkaz: https://doaj.org/article/13c91f809a5f46e7b8f3b22becf24d81

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Akademický článek

Characteristics of AIDS patients in Dutch intensive care units

Autor: M.A.M. Huson, F. Bakhshi-Raiez, M.P. Grobusch, E. de Jonge, N.F. de Keizer, T. van der Poll

Publikováno v: International Journal of Infectious Diseases, Vol 21, Iss S1, p 128 (2014)

Externí odkaz: https://doaj.org/article/e5a84876a5514a2db72d4b13fc53c17d

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Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer

Autor: M. K. Bos, S. W. Lam, G. Motta, J. C. A. Helmijr, C. M. Beaufort, E. de Jonge, J. W. M. Martens, E. Boven, M. P. H. M. Jansen, A. Jager, S. Sleijfer

Publikováno v: Bos, M K, Lam, S W, Motta, G, Helmijr, J C A, Beaufort, C M, de Jonge, E, Martens, J W M, Boven, E, Jansen, M P H M, Jager, A & Sleijfer, S 2023, ' Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer ', Breast Cancer Research and Treatment, vol. 200, no. 2, pp. 271-279 . https://doi.org/10.1007/s10549-023-06965-5
Breast Cancer Research and Treatment, 200(2), 271-279. Springer New York

Background ESR1 mutations have been identified as mechanism for endocrine resistance and are also associated with a decreased overall survival. We assessed ESR1 mutations in circulating tumor DNA (ctDNA) for impact on outcome to taxane-based chemothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7aebbcd0120eb600dc370a3b31b7216
https://pure.eur.nl/en/publications/00ba171e-1ab7-4e84-bef7-427b3ddafd1e

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