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Akademický článek

Behavioural Response of Triatoma infestans (Klug) (Hemiptera: Reduviidae) to Quinazolines

Autor: E. Zerba, A. Cork, D. FernÃƒÂ¡ndez, P. Santo Orihuela, H. Masuh, F. Camps, A. FontÃƒÂ¡n, R. A. Alzogaray

Publikováno v: Molecules, Vol 10, Iss 9, Pp 1190-1196 (2005)

The behavioural responses of the haematophagous bug Triatoma infestans towards some previously identified components of its faeces: 4-methylquinazoline, 2,4- dimethylquinazoline and their mixtures were evaluated using a video tracking system. Fifth i

Externí odkaz: https://doaj.org/article/211569bfb18242918e8f40ace4d17111

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Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer

Autor: Ariella Sasson, Joseph D. Szustakowski, Ryan Golhar, William J. Geese, Stefan Kirov, Han Chang, George Green, Sujaya Srinivasan, Danielle Greenawalt, Kim E. Zerba

Publikováno v: Molecular Diagnosis & Therapy

Introduction Tumor mutational burden (TMB) has emerged as a clinically relevant biomarker that may be associated with immune checkpoint inhibitor efficacy. Standardization of TMB measurement is essential for implementing diagnostic tools to guide tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662517ad8b4a4f52e16b9bfb813cea93
https://doi.org/10.1007/s40291-019-00408-y

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First-Line Nivolumab Plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer (CheckMate 568): Outcomes by Programmed Death Ligand 1 and Tumor Mutational Burden as Biomarkers

Publikováno v: Journal of Clinical Oncology

PURPOSE CheckMate 568 is an open-label phase II trial that evaluated the efficacy and safety of nivolumab plus low-dose ipilimumab as first-line treatment of advanced/metastatic non–small-cell lung cancer (NSCLC). We assessed the association of eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ea6ae4a4189dd4a5b12cd785da56cb
http://europepmc.org/articles/PMC6494267

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A real-world, comparative study of FDA-approved diagnostic assays PD-L1 IHC 28-8 and 22C3 in lung cancer and other malignancies

Autor: Virginia Burns, Sucha Sudarsanam, Cory Batenchuk, Vladislav Chizhevsky, Kim E. Zerba, Maher Albitar, Chelsea Jin

Publikováno v: Journal of Clinical Pathology

AimsAt the time of analysis, two widely used, drug-specific, tumour-cell programmed death ligand 1 (PD-L1) assays were approved by the US Food and Drug Administration for anti-PD-1 therapies: the Dako PD-L1 immunohistochemistry (IHC) 28-8 pharmDx ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5860e023c5dc33392ec684908a408086
http://europepmc.org/articles/PMC6287558

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Practical statistical considerations for investigating anti-tumor treatments in mice

Autor: Kim E. Zerba, David V. Gold, Lixin Lang

Publikováno v: Journal of Applied Statistics. 46:272-285

Anti-tumor treatment outcomes in mouse experiments can be challenging to interpret and communicate accurately. In reporting these experiments, rigorous statistical considerations are commonly absent, although statistical applications have been propos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::745508ac7d9f6ec6cc2e67e6a1d8ecca
https://doi.org/10.1080/02664763.2018.1477925

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A methodology based on insecticide impregnated filter paper for monitoring resistance to deltamethrin inTriatoma infestansfield populations

Autor: E. Zerba, Patricia A. Lobbia, Gastón Mougabure-Cueto, C. Remón

Publikováno v: Medical and Veterinary Entomology. 31:414-426

The domiciliary presence of Triatoma infestans (Klug) (Hemiptera: Reduviidae) after control interventions was reported in recent years. Toxicological studies showed high levels of resistance to pyrethroids suggesting resistance as one of the main cau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de0d6c0e04bb3045e2d820128081d4fb
https://doi.org/10.1111/mve.12252

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