Zobrazeno 1 - 3
of 3
pro vyhledávání: '"E. Yu. Savchik"'
Publikováno v:
Pharmaceutical Chemistry Journal. 49:167-170
The anticoagulant activity of the microcrystalline cellulose sulfate (MCCS) extracted from the wood of Abies sibirica Ledeb (molecular weight 86,000, sulfur substitution level 1.63) were studied in vitro and ex vivo. The antithrombin activity was 87.
Autor:
A. V. Babij, E. Yu. Savchik, E. N. Lapsheva, T. B. Kalinina, Galina Pavlova, N. N. Drozd, Elena Zavyalova, V. A. Makarov, Alexey Kopylov, Andrey V. Golovin, N. N. Mudrik
Publikováno v:
Bulletin of Experimental Biology and Medicine. 156:44-48
RA36 DNA aptamer is a direct anticoagulant prolonging clotting time of human, rabbit, and rat plasma in the thrombin time test. Anticoagulant activity of RA36 is lower than that of recombinant hirudin. During inhibition of human plasma clotting activ
Autor:
N. N. Drozd, E. Yu. Savchik, A. V. Kuchin, I. D. Gurvits, V. A. Makarov, M. A. Torlopov, T. B. Kalinina
Publikováno v:
Pharmaceutical Chemistry Journal. 46:86-91
Rabbit plasma coagulation time in the APTT and ReaClot-heparin tests, antithrombin and anti-factor Xa activities of plasma, and the effective half-life and duration of action increase with dose (0.3 to 10 mg/kg, i.v.) of injected cellulose sulfate (m