Zobrazeno 1 - 10
of 22
pro vyhledávání: '"E. Yaneth Osorio"'
Autor:
E. Yaneth Osorio, Zbigniew Gugala, Grace T. Patterson, Genesis Palacios, Erika Cordova, Ashanti Uscanga-Palomeque, Bruno L. Travi, Peter C. Melby
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inflammation has a role in the pathogenesis of childhood malnutrition. We investigated the effect of malnutrition and inflammatory challenge on bone marrow composition and bone health. We studied an established murine model of moderate acute malnutri
Externí odkaz:
https://doaj.org/article/4bf52d4d474449d2b25ef5f8f5548f24
Autor:
E Yaneth Osorio, Ashanti Uscanga-Palomeque, Grace T Patterson, Erika Cordova, Bruno L Travi, Lynn Soong, Peter C Melby
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011040 (2023)
People are infected with Leishmania donovani when the parasite is deposited in the dermis during the blood meal of the sand fly vector. Most infected people develop a subclinical latent infection, but some develop progressive visceral leishmaniasis.
Externí odkaz:
https://doaj.org/article/51e63ff3f3d04878be86f38528cf7d22
Autor:
Fanping Kong, Omar A Saldarriaga, Heidi Spratt, E Yaneth Osorio, Bruno L Travi, Bruce A Luxon, Peter C Melby
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006165 (2017)
Visceral Leishmaniasis (VL), caused by the intracellular protozoan Leishmania donovani, is characterized by relentlessly increasing visceral parasite replication, cachexia, massive splenomegaly, pancytopenia and ultimately death. Progressive disease
Externí odkaz:
https://doaj.org/article/7dde5d908ddb43a48dac02a25d7fbcf4
Autor:
Alex G Peniche, Diana L Bonilla, Gloria I Palma, Peter C Melby, Bruno L Travi, E Yaneth Osorio
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179084 (2017)
We evaluated the importance of neutrophils in the development of chronic lesions caused by L. Viannia spp. using the hamster as experimental model of American Cutaneous Leishmaniasis (ACL). Neutrophils infiltrated the lesion within the first six hour
Externí odkaz:
https://doaj.org/article/3d73e6ac105247adac6bb16e3650bafe
Autor:
E. Yaneth Osorio, Zbigniew Gugala, Grace T. Patterson, Genesis Palacios, Erika Cordova, Ashanti Uscanga-Palomeque, Bruno L. Travi, Peter C. Melby
Publikováno v:
Frontiers in immunology. 13
Inflammation has a role in the pathogenesis of childhood malnutrition. We investigated the effect of malnutrition and inflammatory challenge on bone marrow composition and bone health. We studied an established murine model of moderate acute malnutri
Autor:
E Yaneth Osorio, Bruno L Travi, Alda M da Cruz, Omar A Saldarriaga, Audrie A Medina, Peter C Melby
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004165 (2014)
Host arginase 1 (arg1) expression is a significant contributor to the pathogenesis of progressive visceral leishmaniasis (VL), a neglected tropical disease caused by the intracellular protozoan Leishmania donovani. Previously we found that parasite-i
Externí odkaz:
https://doaj.org/article/c860c70946a0440e9d9c09751baba7cc
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0242337 (2020)
PLoS ONE, Vol 15, Iss 11, p e0242337 (2020)
Visceral leishmaniasis (VL) is characterized by expansion of myeloid cells in the liver and spleen, which leads to a severe splenomegaly associated with higher risk of mortality. This increased cellularity is thought to be a consequence of recruitmen
Autor:
E Yaneth Osorio, Weiguo Zhao, Claudia Espitia, Omar Saldarriaga, Leo Hawel, Craig V Byus, Bruno L Travi, Peter C Melby
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002417 (2012)
The clinicopathological features of the hamster model of visceral leishmaniasis (VL) closely mimic active human disease. Studies in humans and hamsters indicate that the inability to control parasite replication in VL could be related to ineffective
Externí odkaz:
https://doaj.org/article/8fb589f3cfc14d07ba30eb88609abe07
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008482 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Current drug therapies for cutaneous leishmaniasis are often difficult to administer and treatment failure is an increasingly common occurrence. The efficacy of anti-leishmanial therapy relies on a combination of anti-parasite activity of drugs and t
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