Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E. Ya. Tkachenko"'
Publikováno v:
Human Physiology. 40:197-200
Genome studies in ethnic Russians revealed subjects having a heterozygous genotype with allele C at the single-nucleotide polymorphism rs11562975 (G → C), which is in exon 6 of the TRPM8 temperature-sensitive ion channel gene. The subjects had incr
Publikováno v:
Neuroscience and Behavioral Physiology. 42:654-659
Animal experiments were performed to study the effects of activation of cold- and menthol-sensitive TRPM8 receptors by menthol on thermoregulatory parameters in thermoneutral conditions and on cooling. Total oxygen consumption was measured, along wit
Publikováno v:
Journal of Thermal Biology. 35:428-434
The effects of activation of the cold and menthol sensitive TRPM8 ion channel on different thermoregulatory parameters (total oxygen consumption, carbon dioxide release, respiratory coefficient, vasoconstriction response of skin blood vessels and shi
Autor:
E. Ya. Tkachenko, T. V. Kozyreva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 149:21-25
Susceptibility of thermoregulatory responses to cold to blockage of α(1)- and β-adrenoreceptors differs in health and hypertension. α(1)-Adrenoceptor blockade reduces vessel reactivity during cooling and vessel reaction to cold becomes similar to
Publikováno v:
Bulletin of Experimental Biology and Medicine. 145:291-294
Ionophoretic application of alpha1- and beta-adrenoceptor blockers into the skin produces no effect on the parameters of thermal homeostasis under thermoneutral conditions. alpha1-Adrenoblocker verapamil inhibits cold shivering during fast and slow c
Autor:
T. V. Kozyreva, E. Ya. Tkachenko
Publikováno v:
Human Physiology. 34:221-225
Application of 1% methol, which, along with cold, activates specific thermosensitive ionic channels, changes the number of functioning cold receptors on the skin of the forearm similarly to the cold exposure test; however, it does not affect the numb
Publikováno v:
Journal of Thermal Biology. 30:545-550
The effect of iontophoretic administration of calcium ions to skin in the area of cold stimulus application on the thermal thresholds and the magnitude of cold defense responses in normotensive Wistar and hypertensive inherited stress-induced arteria
Autor:
E. Ya. Tkachenko, T. V. Kozyreva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 127:223-226
Rats without anesthesia and those superficially anesthetized with urethane responded to rapid cooling by two-phase metabolic reactions without changes in core temperature and heart emission. Their vascular reactions started much later than metabolic
Publikováno v:
Bulletin of experimental biology and medicine. 158(3)
Involvement of various areas of the body surface in heat emission response to warming is characterized by a certain succession. The first response preceding the deep body temperature rise is dilation of ear skin vessels. Then, an increase in deep bod
Publikováno v:
Bulletin of experimental biology and medicine. 155(3)
Preliminary non-thermal activation of cold-sensitive TRPM8 ion channel facilitates initiation of the heat-defense responses in homoiothermal animals by decreasing temperature threshold of the vasodilatory response. TRPM8 activation leads to earlier h