Zobrazeno 1 - 10
of 183
pro vyhledávání: '"E. Willcox"'
Publikováno v:
Biogeosciences, Vol 21, Pp 4037-4050 (2024)
The Northeast Greenland Shelf is a region currently considered to be an annual net sink of carbon dioxide (CO2) from the atmosphere. Water from the Northeast Greenland Shelf is advected to the formation regions of North Atlantic Deep Water; therefore
Externí odkaz:
https://doaj.org/article/3a29d7b059604c0eb092b18a4ee9f87d
Autor:
Malte Buschmann, Joshua W. Foster, Anson Hook, Adam Peterson, Don E. Willcox, Weiqun Zhang, Benjamin R. Safdi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The question of what axion mass would give rise to the observed dark matter abundance requires proper modelling of non-linear dynamics of the axion field in the early Universe. Here, the authors use adaptive mesh refinement simulations to predict a m
Externí odkaz:
https://doaj.org/article/e512756827334158824608331d733fc6
Autor:
Sharyn Thomas, Fiyaz Mohammed, Rogier M. Reijmers, Annemarie Woolston, Theresa Stauss, Alan Kennedy, David Stirling, Angelika Holler, Louisa Green, David Jones, Katherine K. Matthews, David A. Price, Benjamin M. Chain, Mirjam H. M. Heemskerk, Emma C. Morris, Benjamin E. Willcox, Hans J. Stauss
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Increasing TCR cell surface expression can potentiate T cell responses to low-concentrations of antigen. Here the authors identify aminoacids in human TCR variable domains that impact its surface expression, and demonstrate how editing these residues
Externí odkaz:
https://doaj.org/article/b91ffe9fd06f4dd8ae5b0aa7c12c5d8e
Autor:
Martin S. Davey, Carrie R. Willcox, Stuart Hunter, Sofya A. Kasatskaya, Ester B. M. Remmerswaal, Mahboob Salim, Fiyaz Mohammed, Frederike J. Bemelman, Dmitriy M. Chudakov, Ye H. Oo, Benjamin E. Willcox
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Human Vδ2+ γδ T cells are thought to be an innate-like T-cell population. Here the authors show the Vδ2+ compartment contains both innate-like Vγ9+ and an adaptive Vγ9- subset that undergoes clonal expansion during viral infection and can infil
Externí odkaz:
https://doaj.org/article/34013345c36840c6887dde5ba30f872e
Autor:
Martin S. Davey, Carrie R. Willcox, Stephen P. Joyce, Kristin Ladell, Sofya A. Kasatskaya, James E. McLaren, Stuart Hunter, Mahboob Salim, Fiyaz Mohammed, David A. Price, Dmitriy M. Chudakov, Benjamin E. Willcox
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
γδ T cells are generally considered innate‐like lymphocytes. Here the authors sequence human γδ T cell receptors (TCR) to show focusing of the private Vδ1 TCR repertoire, suggesting that, unlike Vδ2 T cells, the Vδ1 T cell compartment has ad
Externí odkaz:
https://doaj.org/article/e1ccfb7e084e42f698fa39ef31fcea3d
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/11855f9025784f6598502605235ae297
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Naturally acquired protective immunity to Plasmodium falciparum malaria is mainly antibody-mediated. However, other cells of the innate and adaptive immune system also play important roles. These include so-called unconventional T cells, which expres
Externí odkaz:
https://doaj.org/article/c638b35b3f8744abb8be4732d1680e5b
Autor:
Shahd Talhouni, Wakkas Fadhil, Nigel P. Mongan, Lara Field, Kelly Hunter, Sogand Makhsous, Alexandre Maciel-Guerra, Nayandeep Kaur, Ausrine Nestarenkaite, Arvydas Laurinavicius, Benjamin E. Willcox, Tania Dottorini, Ian Spendlove, Andrew M. Jackson, Mohammad Ilyas, Judith M. Ramage
Publikováno v:
Frontiers in Immunology. 14
IntroductionCharacterization of the tumour immune infiltrate (notably CD8+ T-cells) has strong predictive survival value for cancer patients. Quantification of CD8 T-cells alone cannot determine antigenic experience, as not all infiltrating T-cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc5cc8cc7f3a0d897f2135767688e0d
https://doi.org/10.3389/fimmu.2023.1057292
https://doi.org/10.3389/fimmu.2023.1057292
Publikováno v:
Frontiers in Immunology. 14
T cell receptor (TCR) gene modified T cells are a promising form of adoptive cellular therapy against human malignancies and viral infections. Since the first human clinical trial was carried out in 2006, several strategies have been developed to imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d342e5324b5b80bfbe9938da597176e8
https://doi.org/10.3389/fimmu.2023.1148890
https://doi.org/10.3389/fimmu.2023.1148890
Autor:
Jeanne E. Poole, Marye J. Gleva, Ulrika Birgersdotter‐Green, Kelley R. H. Branch, Rahul N. Doshi, Tariq Salam, Thomas C. Crawford, Mark E. Willcox, Arun M. Sridhar, Ghiath Mikdadi, Sean C. Beinart, Yong‐Mei Cha, Andrea M Russo, Ron K. Rowbotham, Joseph Sullivan, Laura M. Gustavson, Kaisa Kivilaid
Publikováno v:
Journal of Cardiovascular Electrophysiology. 33:831-842
A wearable cardioverter defibrillator (WCD) is indicated in appropriate patients to reduce the risk for sudden cardiac death. Challenges for patients wearing a WCD have been frequent false shock alarms primarily due to electrocardiogram noise and wea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0ab7d80b168b81850cb5c0d5f7bfb9
https://doi.org/10.1111/jce.15417
https://doi.org/10.1111/jce.15417