Zobrazeno 1 - 10
of 17
pro vyhledávání: '"E. W. Fleischman"'
Autor:
E. W. Fleischman, O. I. Sokova, A. V. Popa, O. P. Kirichenko, L. N. Konstantinova, N. F. Metelkova
Publikováno v:
Онкогематология, Vol 0, Iss 4, Pp 12-16 (2022)
Peculiar age distribution of clinically significant recurring chromosome abnormalities was found as a result of investigation of526AML patients (249 children and 277 adults). Thus t(8;21) was more frequently detected in age from 2 to 10 years, t(15;1
Externí odkaz:
https://doaj.org/article/2b1d2cbd3e564918afd3ec6dd7efdea7
Publikováno v:
Онкогематология, Vol 11, Iss 1, Pp 14-23 (2016)
In this review we present current state of cytogenetic and molecular genetic diagnostics of various aberrations in infant acute leukemias together with our own experience in this field. A complex characteristic of acute leukemias was performed for bo
Externí odkaz:
https://doaj.org/article/dd9578b3cb124bc99aef1222f0903321
Deletion of theAlu-VpA/MycL1 (1p34.3) locus is a negative prognostic sign in human colorectal cancer
Publikováno v:
Molecular Biology. 34:337-344
We examined deletions of the short arm of chromosome 1 and aberrations of the microsatellite locusAlu-VpA/MycL1 (1p34.3) in human primary colorectal adenocarcinomas. Cytogenetically discernible deletions in 1p were found in 45% (14/31) of informative
Autor:
E W, Fleischman, S, Reshmi, M A, Frenkel, W I, Konovalova, G P, Guleva, O E, Kulagina, L N, Konstantinova, N N, Tupitsyn, J D, Rowley
Publikováno v:
Genes, chromosomescancer. 24(2)
We describe a patient with acute myeloblastic leukemia (AML-M0) whose cells had a t(2;11)(p21;q23). Fluorescence in situ hybridization analysis with a probe for MLL showed that it was split, hybridizing to both the derivative 2 and 11 chromosomes. Ni
Publikováno v:
Human genetics. 86(5)
The data of the chromosome abnormalities in 15 colorectal tumors are presented. Rearrangements of the short arm of chromosome 17, leading to deletions of this arm or its part were noted in 12 tumors; in 2 other cases, one of the homologs of pair 17 w
Autor:
G. P. Puchkova, E. W. Fleischman, E. L. Prigogina, S. A. Balakirev, N. A. Zakhartchenko, M. A. Volkova, M. A. Frenkel, L. N. Konstantinova
Publikováno v:
Human Genetics. 58:285-293
Results of chromosome studies of blood and bone marrow cells from 101 patients with Ph1 positive chronic myeloid leukemia (CML) confirm the assumptions that clinical and morphologic manifestations of the disease correlate with karyotype peculiarities
Publikováno v:
Human Genetics. 50:101-104
Two male patients with myeloproliferative disorders (osteomyelosclerosis in one and CML in the other) were found to have a chromosomal marker 20q- in blood cells (unstimulated short time cultures). Marked erythropoietic disturbances were not revealed
Autor:
S. A. Balakirev, S A Majakova, E. W. Fleischman, I. S. Peterson, O. E. Kulagina, N V Khvatova, G. P. Puchkova, M. A. Frenkel, E. L. Prigogina
Publikováno v:
Human Genetics. 53:5-16
The karyotype of leukemic cells of 78 acute leukemia patients (37 ANLL, 34ALL, and 7 of unknown type) was studied by means of G-banding. Chromosomal abnormalities were found in 50 patients (72%). Chromosomes 8,21,5,7,11, and 19 were preferentially in
Autor:
E. L. Prigogina, E. W. Fleischman
Publikováno v:
Human Genetics. 35:269-279
Karyotypes of 30 malignant lymphomas were studied with the aid of G-banding. Frequent occurrence of rearranged chromosomes 14 and 11 was noted. In several tumors, identical acrocentric markers, appearing after translocation of the long arm of chromos
Autor:
E. W. Fleischman, E. L. Prigogina
Publikováno v:
Human Genetics. 30:113-119
The study of chromosome banding pattern of leukaemic cells in 15 patients with CML revealed t(9;22) in all cases. Similar additional chromosome abnormalities were observed in the terminal stage of the disease in 5 of 9 patients with aneuploid cell li