Zobrazeno 1 - 10 of 24 pro vyhledávání: '"E. W. Carney"'
2
The Effects of Feed Restriction during in Utero and Postnatal Development in Rats
Autor: Phyllis K. Anderson, E. W. Carney, Mary Sue Marty, J. W. Crissman, Carol L. Zablotny, Michael R. Woolhiser, Michael P. Holsapple
Publikováno v: Toxicological Sciences. 82:237-249
This study determined the effects of feed restriction (FR) during in utero and postnatal life on standard reproductive toxicity and developmental immunotoxicity end points. Groups of 26 time-mated CD rats were fed various amounts of Purina 5002 diet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac796b11c73bab88761d6fb70881229
https://doi.org/10.1093/toxsci/kfh249
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3
Analysis of resulting data from estrogen receptor reporter gene assays
Autor: E. W. Carney, Chris Gennings, Grantley D. Charles, B. Bhaskar Gollapudi, Tim Zackarewski
Publikováno v: Journal of Agricultural, Biological, and Environmental Statistics. 8:84-104
Screening methods for detecting single chemicals and chemical mixtures that have endocrine effects are of increasing importance. One such assay used by many laboratories to screen for potential estrogenicity is the estrogen receptor (ER) transcriptio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::178847afd158807cc5b2316c8304f819
https://doi.org/10.1198/1085711031030
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5
Evaluation of the Male Pubertal Onset Assay to Detect Testosterone and Steroid Biosynthesis Inhibitors in CD Rats
Autor: E. W. Carney, Mary Sue Marty, J. W. Crissman
Publikováno v: Toxicological Sciences. 60:285-295
The male pubertal onset assay has been recommended by the Endocrine Disrupter Screening and Testing Advisory Committee (EDSTAC) as an alternate Tier I screening assay to detect potential endocrine-active chemicals (EACs). Recently, this assay was eva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9798a6cbb1569856bfe4eb4317df3455
https://doi.org/10.1093/toxsci/60.2.285
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6
Optimization of an estrogen receptor-? transcriptional activation assay for testing a diverse spectrum of chemicals
Autor: E. W. Carney, J. Clemons, B. Bhaskar Gollapudi, Timothy R. Zacharewski, Chris Gennings, Grantley D. Charles
Publikováno v: Journal of Applied Toxicology. 20:449-454
Estrogen receptor (ER) transactivation assays were initially designed to study endogenous mechanisms of steroid hormone action, but more recently have been used to assess industrial chemicals for potential estrogenic activity. Given the diverse spect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4bb4d7ae714986d9cf5f77e8f1a7b655
https://doi.org/10.1002/1099-1263(200011/12)20:6<449::aid-jat712>3.0.co
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7
Developmental Toxicity of Diethanolamine Applied Cutaneously to CD Rats and New Zealand White Rabbits
Autor: Mary Sue Marty, E. W. Carney, D A Neptun, T L Neeper-Bradley
Publikováno v: Regulatory Toxicology and Pharmacology. 30:169-181
Diethanolamine (DEA) was administered cutaneously to pregnant CD rats and New Zealand White rabbits during the periods of major organogenesis, Gestation Days 6-15 for rats and 6-18 for rabbits. Doses employed were 0, 150, 500, and 1500 mg/kg/day for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5334ec0e61c24396cf426285bede3e
https://doi.org/10.1006/rtph.1999.1308
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8
Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta- estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor
Autor: Mary Sue Marty, E. W. Carney, J. W. Crissman
Publikováno v: Toxicological Sciences. 52:269-277
The Endocrine Disrupter Screening and Testing Advisory Committee has recommended the female pubertal onset assay as a Tier I test to detect potential endocrine-disrupting chemicals (EDs). We evaluated this assay's ability to detect EDs acting through
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7c4af6de619464244fdebbbf045769
https://doi.org/10.1093/toxsci/52.2.269
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9
Identifying subsets of complex mixtures most associated with complex diseases: polychlorinated biphenyls and endometriosis as a case study
Autor: E. W. Carney, Chris Gennings, Roy Sabo
Publikováno v: Epidemiology (Cambridge, Mass.). 21
Exploratory statistical analyses have been conducted on an epidemiologic data set in which the relationship was examined between exposure to polychlorinated biphenyl (PCB) mixtures and risk of endometriosis in women. In that study, the association be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3634dcb86da7ed85dd2e1ee9c815a99e
https://pubmed.ncbi.nlm.nih.gov/21422968
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10
Improved development of rabbit one-cell embryos to the hatching blastocyst stage by culture in a defined, protein-free culture medium
Autor: E. W. Carney, R H Foote
Publikováno v: Reproduction. 91:113-123
In Exp. 1, Medium 199 and Medium RD (RPMI-1640 and Dulbecco's MEM, 1:1 v/v) were compared in a 2 x 2 factorial design by supplementing each with 15 mg bovine serum albumin (BSA)/ml of 1 mg polyvinyl alcohol (PVA)/ml. All media contained 5 micrograms
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efae18df9196428f9fc4bab5641a2b77
https://doi.org/10.1530/jrf.0.0910113
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