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pro vyhledávání: '"E. Vijaya Bharathi"'
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Autor:
Shashidhar S. Jatiani, Balireddy Akula, E. Premkumar Reddy, Poornima Ramkumar, Rinku Jain, E. Vijaya Bharathi, Aneel K. Aggarwal, Stephen C. Cosenza, M. V. Ramana Reddy, Vinay K. Billa, Muralidhar R. Mallireddigari, D. R. C. Venkata Subbaiah, Rodrigo Vasquez-Del Carpio, Venkat R. Pallela
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:521-544
Several families of protein kinases have been shown to play a critical role in the regulation of cell cycle progression, particularly progression through mitosis. These kinase families include the Aurora kinases, the Mps1 gene product and the Polo Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb9efe427187663e69beb25a050e321
https://doi.org/10.1016/j.bmc.2015.11.045
https://doi.org/10.1016/j.bmc.2015.11.045
Autor:
M. V. Ramana Reddy, E. Premkumar Reddy, Venkat R. Pallela, Muralidhar R. Mallireddigari, Amol Padgaonkar, D. R. C. Venkata Subbaiah, Stacey J. Baker, Saikrishna Athuluri-Divakar, Rodrigo Vasquez-Del Carpio, Balireddy Akula, Vinay K. Billa, E. Vijaya Bharathi, Stephen C. Cosenza
Publikováno v:
Journal of Medicinal Chemistry
The success of imatinib, a BCR-ABL inhibitor for the treatment of chronic myelogenous leukemia, has created a great impetus for the development of additional kinase inhibitors as therapeutic agents. However, the complexity of cancer has led to recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0f24b374ef93e3e537acf13db90e79
https://doi.org/10.1021/jm401073p
https://doi.org/10.1021/jm401073p
Autor:
M. Kashi Reddy, E. Vijaya Bharathi, Ahmed Kamal, Manika Pal Bhadra, T. Lakshminarayan Reddy, D. Dastagiri, S.N.C.V.L. Pushpavalli, M. Janaki Ramaiah, J. Surendranadha Reddy, A. Viswanath, T. Basha Shaik
Publikováno v:
European Journal of Medicinal Chemistry. 46:691-703
A series of new 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydro quinazolinone hybrids with different linker architectures have been designed and synthesized. These compounds have been evaluated for their anticancer activity. One of the compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28350306d69e2f50d1fd91590cf823e
https://doi.org/10.1016/j.ejmech.2010.12.004
https://doi.org/10.1016/j.ejmech.2010.12.004
Autor:
Ahmed Kamal, Farheen Sultana, D. Dastagiri, Subrata Sen, M. Janaki Ramaiah, Aarti Juvekar, Surekha M. Zingde, A. Viswanath, J. Surendranadha Reddy, E. Vijaya Bharathi, Manika Pal-Bhadra, S.N.C.V.L. Pushpavalli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3310-3313
A series of novel anthranilamide linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates were prepared and evaluated for their anticancer activity. The effects of three promising PBD conjugates on cell cycle of cancerous cell line A375 were investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa1c07b29a5866f2a1af663590e8efb
https://doi.org/10.1016/j.bmcl.2010.04.037
https://doi.org/10.1016/j.bmcl.2010.04.037
Publikováno v:
Tetrahedron Letters. 49:348-353
A mild and efficient procedure has been developed for the monosulfonylation of various amines using mesyl or tosyl chlorides in water at room temperature to afford the corresponding sulfonamides in high yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5d9fdb957df5fa84cf84ea297ac05d
https://doi.org/10.1016/j.tetlet.2007.11.044
https://doi.org/10.1016/j.tetlet.2007.11.044
Autor:
E. Vijaya Bharathi, A. Hari Babu, K. Venkata Ramana, A. Venkata Ramana, Ahmed Kamal, M. Shiva Kumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2621-2623
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines via azido reductive cyclization process employing FeCl3–NaI reagent system. This methodology has been extended for the preparation of new nicotinamido-pyrrolobenzodiazepine hybrids linked through pipe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49517e0e5d1a86f896b06f76568cefd
https://doi.org/10.1016/j.bmcl.2005.03.051
https://doi.org/10.1016/j.bmcl.2005.03.051
Autor:
E. Premkumar Reddy, E. Vijaya Bharathi, Amol Padgaonkar, Muralidhar R. Mallireddigari, Venkat R. Pallela, Vinay K. Billa, Hua Lv, James M. Gallo, D. R. C. Venkata Subbaiah, Balaiah Akula, Stephen C. Cosenza, M. V. Ramana Reddy
Publikováno v:
Journal of medicinal chemistry. 56(13)
A series of novel (E)-N-aryl-2-arylethenesulfonamides (6) were synthesized and evaluated for their anticancer activity. Some of the compounds in this series showed potent cytotoxicity against a wide spectrum of cancer cell-lines (IC50 values ranging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928ab766bdcfc31e9ffeed27dcd7c40b
https://pubmed.ncbi.nlm.nih.gov/23750455
https://pubmed.ncbi.nlm.nih.gov/23750455
Autor:
Pranjal Sarma, Farheen Sultana, Ahmed Kamal, E. Vijaya Bharathi, M. Janaki Ramaiah, S.N.C.V.L. Pushpavalli, Arutla Viswanath, Manika Pal Bhadra, G. Ramakrishna, A. Lavanya, Jayanti Naga Srirama Chandra Murty
Publikováno v:
Anti-cancer agents in medicinal chemistry. 13(10)
A series of new diaryl ether linked pyrrolobenzodiazepine (PBD) conjugates (4a-i, 5a-i and 6a-f) was synthesized and evaluated for their anticancer activity against a panel of 11 human cancer cell lines. These conjugates exhibited significant antican
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b636a69734e71a0235c97b8602712f3d
https://pubmed.ncbi.nlm.nih.gov/23438825
https://pubmed.ncbi.nlm.nih.gov/23438825
Autor:
M. Janaki Ramaiah, Ahmed Kamal, T. Lakshminarayan Reddy, M. Victor Prem Sagar, M. Kashi Reddy, Manika Pal-Bhadra, E. Vijaya Bharathi, D. Dastagiri, J. Surendranadha Reddy, S.N.C.V.L. Pushpavalli
Publikováno v:
European journal of medicinal chemistry. 46(12)
A series of anilino substituted pyrimidine sulfonamides were prepared and evaluated for their anticancer activity. These sulfonamides showed promising activity with IC 50 values ranging from 5.6 to 12.3 μM. The detailed biological aspects of some of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30493121df7f80ac1272932b007fe4c9
https://pubmed.ncbi.nlm.nih.gov/22000207
https://pubmed.ncbi.nlm.nih.gov/22000207