Zobrazeno 1 - 10
of 10
pro vyhledávání: '"E. V. Lysogorskaia"'
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 16, Iss 0, Pp 4-10 (2024)
Search for agents for the add-on therapy of multiple sclerosis (MS) that can enhance the effect of first-line MS disease-modifying therapy (DMTs) is a very current issue. Such a boost is needed to reduce the need to switch to second-line DMTs, whose
Externí odkaz:
https://doaj.org/article/dd91818ecb6240a0adc581fd4e436edc
Autor:
M. N. Zakharova, I. A. Avdunina, E. V. Lysogorskaia, A. A. Vorobyeva, M. V. Ivanova, A. V. Chervyakov, A. V. Vasiliev
Publikováno v:
Нервно-мышечные болезни, Vol 0, Iss 4, Pp 4-11 (2015)
This article is a critical review of palliative care for ALS patients in Russia. The authors summarize the principal European guidelines, analyze local practice guidelines regarding palliative care, present their experience in ALS patients care in a
Externí odkaz:
https://doaj.org/article/ec9c2ae5c897433fbd6c69c428eddd08
Autor:
Sergei N. Illarioshkin, N. Yu. Abramycheva, I A Kochergin, Yu A Shpilyukova, E. V. Lysogorskaia, M. N. Zakharova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 167:667-670
Insoluble protein inclusions accumulate in somatic cells in amyotrophic lateral sclerosis. The most common gene mutations associated with this pathology are SOD1 and C9orf72. Protein aggregates can be removed from cells by autophagy. We studied the r
The review provides modern understanding of the pathogenesis of progressive multifocal leukoencephalopathy (PML), a severe and potentially fatal form of multiple-lesion disorder of the brain white matter. Information about the frequency of its develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4196ec6674a7384db64ecaadbfc69a3a
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 118(8. Vyp. 2)
The article describes the first case of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis, developed during treatment with natalizumab. The causes, possibly, influencing the outcome of the disease, are analyzed.Прив
Autor:
A.V. Rossokhin, Mariya S. Stepanova, Anna A. Moroz, Sergey N. Illarioshkin, E. V. Lysogorskaia, M. N. Zakharova, Nataliya Yu Abramycheva
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 17:135-141
Our objective was to search for mutations in genes SOD1, TARDBP, C9orf72, ANG, ATXN2 and VEGF in Russian patients with amyotrophic lateral sclerosis (ALS). A group of 208 Russian patients with ALS was examined. Molecular genetic analysis was conducte
Autor:
M. N. Zakharova, Sergey N. Illarioshkin, A.V. Rossokhin, E. V. Lysogorskaia, N. Yu. Abramycheva
Publikováno v:
Molecular Biology. 47:751-757
Molecular modeling is a promising method for assessing protein structures that is capable of presenting an energetically beneficial protein conformation with atomic precision. This method is of great importance for studying molecular interactions and
Publikováno v:
Neurochemical Journal. 6:233-238
Our review is focused on new aspects of the pathogenesis of amyotrophic lateral sclerosis (ALS); it considers the hypothesis that disturbances in transcription have a substantial role in ALS. We described the functions of ALS-related genes whose prot
Autor:
A. A. Ustyugov, M. S. Stepanova, Andrey P. Smirnov, I. V. Khritankova, O. D. Razinskaya, N.Y. Abramycheva, A. V. Maltsev, Skvortsova Vi, Natalia Ninkina, E. A. Kovrazhkina, Michail S. Kukharsky, Vladimir L. Buchman, Johnathan Cooper-Knock, Sergey N. Illarioshkin, Sergey O. Bachurin, M N Zakharova, E. V. Lysogorskaia
Cohorts of amyotrophic lateral sclerosis (ALS) patients and control individuals of Caucasian origin from the Central European Russia (Moscow city and region) were analyzed for the presence of hexanucleotide repeat GGGGCC expansion within the first in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075dea6661f93cfb09f68716461bfea1
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 112(11)
Genetic predisposition plays an important role in the development of amyotrophic lateral sclerosis (ALS). One of the most promising candidate genes in ALS is the vascular endothelial growth factor (VEGF) gene. In a Russian population, 192 ALS patient