Zobrazeno 1 - 10
of 11
pro vyhledávání: '"E. V. Batrakova"'
Publikováno v:
Кубанский научный медицинский вестник, Vol 0, Iss 4, Pp 13-17 (2017)
Aim. The aim of the work was evaluation of physical development of preschool children of rural area of Krasnodar Krai. Materials and methods. Research was conducted on the base of six municipal preschool establishments of rural area of Krasnodar Krai
Externí odkaz:
https://doaj.org/article/190a4a9706f343acafb6d12235a7e4af
Publikováno v:
Кубанский научный медицинский вестник, Vol 0, Iss 4, Pp 13-17 (2017)
Aim. The aim of the work was evaluation of physical development of preschool children of rural area of Krasnodar Krai. Materials and methods. Research was conducted on the base of six municipal preschool establishments of rural area of Krasnodar Krai
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(2)
Pluronic block copolymer, P85, inhibits the P-glycoprotein (Pgp) drug efflux system and increases the permeability of a broad spectrum of drugs in the blood-brain barrier (BBB). This study examines the mechanisms by which P85 inhibits Pgp using bovin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(2)
Drug delivery across the blood-brain barrier is limited by several mechanisms. One important mechanism is drug efflux, mediated by several transport proteins, including P-glycoprotein. The goal of this work was to examine the effect of a novel drug d
Publikováno v:
Pharmaceutical research. 16(9)
Previous studies demonstrated that inhibition of P glycoprotein (P-gp) by Pluronic P85 (P85) block copolymer increases apical (AP) to basolateral (BL) transport of rhodamine 123 (R123) in the polarized monolayers of bovine brain microvessel endotheli
Publikováno v:
Pharmaceutical research. 16(3)
Using monolayers of human pancreatic adenocarcinoma cells (Panc-1) that express multidrug resistance-associated protein (MRP), the present work investigates the effects of Pluronic block copolymers on the functional activity of MRP.The studies examin
Publikováno v:
Pharmaceutical research. 15(10)
Using polarized bovine brain microvessel endothelial cells (BBMEC) monolayers as in vitro model of the blood brain barrier and Caco-2 monolayers as a model of the intestinal epithelium, the present work investigates the effects of Pluronic P85 block
Publikováno v:
Pharmaceutical research. 15(6)
The present work characterizes the effects of Pluronic copolymers on the transport of a P-gp-dependent probe, rhodamine 123 (R123) in Caco-2 cell monolayers.The accumulation and efflux studies were performed on the confluent Caco-2 monolayers using f
Publikováno v:
Biochemistry international. 26(4)
Pluronic P85 (poly(oxyethylene)-poly(oxypropylene) block copolymer) was used for in vitro delivery of [gamma-32P]ATP into intact Jurkat cells. Negatively charged ATP molecules are not able to penetrate cell plasma membrane. Hence, exogenous [gamma-32
Publikováno v:
Biotechnology and applied biochemistry. 12(1)
In order to impart an ability for receptor-independent transmembrane transfer to water-soluble proteins, it has been suggested that they be hydrophobized by lipid groups (fatty acids, etc.). To this end, systems of reversed micelles of surfactants in