Výsledky vyhledávání - "E. V. Avvedimento"

The biological functions of A-kinase anchor proteins

Autor: A, Feliciello, M E, Gottesman, E V, Avvedimento

Publikováno v: Journal of molecular biology. 308(2)

cAMP-dependent protein kinase is targeted to discrete subcellular locations by a family of specific anchor proteins (A-kinase anchor proteins, AKAPs). Localization recruits protein kinase A (PKA) holoenzyme close to its substrate/effector proteins, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::206ec4f998d2d12f10b88a1ef2f111f3
https://pubmed.ncbi.nlm.nih.gov/11327755

Zobrazit plný text záznamu

Membrane-bound protein kinase A inhibits smooth muscle cell proliferation in vitro and in vivo by amplifying cAMP-protein kinase A signals

Autor: Antonio Feliciello, Adriana Gallo, Massimo Chiariello, Giancarlo Troncone, E. V. Avvedimento, Ciro Indolfi, Luigi Cavuto, Daniele Torella, Giovanna Allevato, Carmela Coppola, Eugenio Stabile, Emilio Di Lorenzo, Cinzia Perrino

Publikováno v: Scopus-Elsevier

Abstract —cAMP-dependent protein kinase is anchored to discrete cellular compartments by a family of proteins, the A-kinase anchor proteins (AKAPs). We have investigated in vivo and in vitro the biological effects of the expression of a prototypic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452a2c49c1ea7dbf3ff69b0f7f74f597
https://pubmed.ncbi.nlm.nih.gov/11179200

Zobrazit plný text záznamu

Hereditary nonpolyposis coloretal cancer: identification of novel germline mutations in two kindreds not fulfulling the Amsterdam criteria. Mutations in brief no. 203. Online

Autor: B, Quaresima, C, Grandinetti, F, Baudi, P, Tassone, V, Barbieri, S, Conforti, E V, Avvedimento, F, Costanzo, S, Venuta

Publikováno v: Human mutation. 12(6)

Hereditary nonpolyposis colon cancer results from heritable defects in the MLH1, MSH2, PMS1 and PMS2 genes, which encode proteins involved in the mismatch repair process. In this work we report the identification of two novel germline mutations in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e5966bb5c7ce2049cb91271ac955833
https://pubmed.ncbi.nlm.nih.gov/10671064

Zobrazit plný text záznamu

In vivo gene transfer: prevention of neointima formation by inhibition of mitogen-activated protein kinase kinase

Autor: Antonio Leccia, E. V. Avvedimento, Antonio Pisani, Alaide Chieffo, A. Coppola, E. Di Lorenzo, Giovanni Esposito, Massimo Chiariello, Antonio Rapacciuolo, Ciro Indolfi

Publikováno v: ResearcherID

The mitogen-activated protein kinase kinase (MAPKK) is a protein downstream ras which is rapidly activated in cells stimulated with various extracellular signals. These proteins are believed to play a pivotal role in integrating and transmitting tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b786f1fcda25dd5c075899007f8b61a6
https://pubmed.ncbi.nlm.nih.gov/9464861

Zobrazit plný text záznamu

Inhibition of c-ras reactivates thyroglobulin synthesis in middle-T transformed thyroid cells

Autor: B, Di Jeso, A, Feliciello, F, Pacifico, A, Iannelli, F, D'Armiento, D, Liguoro, P, Giuliano, G, Ferulano, E V, Avvedimento

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(10)

Differentiated thyroid cells expressing polyoma Middle-T became transformed and tumorigenic when injected into syngenic animals. The expression of thyroglobulin was greatly reduced and no longer responsive to thyrotropin (TSH) and to cAMP. Inhibition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e7c90d32b5ef689dc4a1585c9e00446
https://pubmed.ncbi.nlm.nih.gov/8845309

Zobrazit plný text záznamu

[Gene therapy for the treatment of restenosis after coronary angioplasty]

Autor: A, Rapacciuolo, C, Indolfi, E, Di Lorenzo, G, Esposito, E, Stabile, A M, Stingone, E V, Avvedimento, M, Condorelli, M, Chiariello

Publikováno v: Cardiologia (Rome, Italy). 39(12)

Accumulation and proliferation of vascular smooth muscle cells are associated with atherosclerosis and hypertension. Proliferation of smooth muscle cells constitutes a major pathological event responsible for long-term failure of coronary and periphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2391c1bec146ad8d71427e3c1342da73
https://pubmed.ncbi.nlm.nih.gov/7781002

Zobrazit plný text záznamu

A polymorphism (G--A transition) in the -78 position of the apolipoprotein A-I promoter increases transcription efficiency

Autor: E, Angotti, E, Mele, F, Costanzo, E V, Avvedimento

Publikováno v: The Journal of biological chemistry. 269(26)

AG--A transition at -78 base pairs from the transcription start site of the apolipoprotein A-I (apoA-I) gene has been associated with increased apoA-I serum levels in humans. We report here that this mutation (G--A) increases significantly (5-7-fold)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b2cace7dcb85d585cb30e895abf35cd
https://pubmed.ncbi.nlm.nih.gov/8021234

Zobrazit plný text záznamu

Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen genes

Autor: S, Boast, M W, Su, F, Ramirez, M, Sanchez, E V, Avvedimento

Publikováno v: The Journal of biological chemistry. 265(22)

The 3500-base pair region located immediately upstream of the transcriptional start site of the human pro-alpha 2(I) collagen gene contains all the sequences necessary for cell-specific transcription. In transient expression assays, the pro-alpha 2(I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aff5360560c7e1eb18a7685e4ce7ff04
https://pubmed.ncbi.nlm.nih.gov/2376598

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání