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Uncommon Presentation of Granulomatosis with Polyangiitis Mimicking Metastatic Lung Cancer

Autor: Johanna Elversang, Karl Emil Nelveg-Kristensen, Bonnie Colville-Ebeling, Johan Löfgren, E. Urbanska, Wladimir Szpirt

Publikováno v: Clinics and Practice, Vol 11, Iss 42, Pp 293-302 (2021)
Clinics and Practice

Diagnosis of anomalous intrathoracic lesions may be challenging and require a multidisciplinary approach. We present a case of granulomatosis with polyangiitis (GPA) clinically and radiologically mimicking metastatic lung cancer with a bilateral pulm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e3786239e38aae008e5079fb81c01f
https://doi.org/10.3390/clinpract11020042

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Acquired Intergenic ANK3-RET Fusion as a Pralsetinib-Responsive Mechanism of Resistance to Osimertinib in EGFR-Mutated NSCLC

Autor: Eric Santoni-Rugiu, Jens Benn Sørensen, Linea Melchior, E. Urbanska, Junia Costa

The unavoidable progression of EGFR-mutated NSCLC on EGFR-TKIs forces us to discover solutions for further therapies. Herein, we discuss the necessity of accurate genomic mapping of progressive disease illustrated by a patient case. Tumor rebiopsies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72e57f61b8220b080bb1db47fd6aa70

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Intracranial Response of ALK+ Non-Small-cell Lung Cancer to Second-line Dose-escalated Brigatinib After Alectinib Discontinuation Due to Drug-induced Hepatitis and Relapse After Whole Brain Radiotherapy Followed by Stereotactic Radiosurgery

Autor: Linea Cecilie Melchior, Jonathan Frederik Carlsen, E. Urbanska, Jens Benn Sørensen, Eric Santoni-Rugiu

Publikováno v: Urbanska, E M, Santoni-Rugiu, E, Melchior, L C, Carlsen, J F & Sørensen, J B 2021, ' Intracranial Response of ALK + Non-Small-cell Lung Cancer to Second-line Dose-escalated Brigatinib After Alectinib Discontinuation Due to Drug-induced Hepatitis and Relapse After Whole Brain Radiotherapy Followed by Stereotactic Radiosurgery ', Clinical Lung Cancer, vol. 22, no. 4, pp. e528-e532 . https://doi.org/10.1016/j.cllc.2020.04.012

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecff3da66a5aaf442d0368a7f30bb832
https://curis.ku.dk/ws/files/279191393/PIIS1525730420301352.pdf

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Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of ALK-Rearranged NSCLC: ALK- and BRAF-Mutations Followed by Epithelial-Mesenchymal Transition

Autor: E. Urbanska, Linea Melchior, Junia Costa, Jens Benn Sørensen, Eric Santoni-Rugiu

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 2847, p 2847 (2020)
Urbanska, E M, Sørensen, J B, Melchior, L C, Costa, J C & Santoni-Rugiu, E 2020, ' Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of ALK-Rearranged NSCLC : ALK-and BRAF-Mutations Followed by Epithelial-Mesenchymal Transition ', International Journal of Molecular Sciences (Online), vol. 21, no. 8, 2847 . https://doi.org/10.3390/ijms21082847
International Journal of Molecular Sciences

Anaplastic lymphoma-kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) is prone to developing heterogeneous, only partly known mechanisms of resistance to ALK-tyrosine-kinase-inhibitors (ALK-TKIs). We present a case of a 38-year old male, who

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78894ef1b1e66bbedfdb6a4198ac7b8e
https://www.mdpi.com/1422-0067/21/8/2847

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