Zobrazeno 1 - 10
of 38
pro vyhledávání: '"E. Toki"'
Autor:
M. Efthimiou, P. Petrikis, E. Toki, V. Siafaka, P. Fakitsa, A. Karampas, G. Georgiou, T. Hyphantis
Publikováno v:
European Psychiatry, Vol 64, Pp S809-S810 (2021)
Introduction People with schizophrenia are considered to be within the most stigmatized social groups. Accurate and efficient detection of stigma and its correlates is essential in patients with psychosis. Objectives The purpose of this study was t
Externí odkaz:
https://doaj.org/article/05b62da85cd745d8a6730286d8bba194
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
A quaternary ammonium-based drug-linker has been developed to expand the scope of antibody–drug conjugate (ADC) payloads to include tertiary amines, a functional group commonly present in biologically active compounds. The linker strategy was exemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01277dcf190fe027b1aa165ef0569aff
https://doi.org/10.1158/1535-7163.c.6538699.v1
https://doi.org/10.1158/1535-7163.c.6538699.v1
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
Pharmacokinetic profile of clearance for three ADCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f40a60bf104249e877111afed1bfdb6
https://doi.org/10.1158/1535-7163.22507471
https://doi.org/10.1158/1535-7163.22507471
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
Plasma stability of quaternary ammonium linker in rodent plasma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af650b3133fc7e21796e5772ffd33361
https://doi.org/10.1158/1535-7163.22507474
https://doi.org/10.1158/1535-7163.22507474
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
Experimental details for the chemical synthesis of the drug-linkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b83380d151e3b1739d6b2739f97589
https://doi.org/10.1158/1535-7163.22507477.v1
https://doi.org/10.1158/1535-7163.22507477.v1
Autor:
Patrick J. Burke, Ivan Stone, Julia H. Cochran, Peter D. Senter, Joshua H. Hunter, Brian E. Toki, Thomas A. Pires, Joseph Z. Hamilton, Jocelyn R. Setter, Scott C. Jeffrey, Kristine A. Gordon, Robert P. Lyon, Kim K. Emmerton, Andrew B. Waight, Weiping Zeng
Publikováno v:
Molecular Cancer Therapeutics. 15:938-945
A quaternary ammonium-based drug-linker has been developed to expand the scope of antibody–drug conjugate (ADC) payloads to include tertiary amines, a functional group commonly present in biologically active compounds. The linker strategy was exemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cbdbff521e3af5c951cb2630d2231a
https://doi.org/10.1158/1535-7163.mct-16-0038
https://doi.org/10.1158/1535-7163.mct-16-0038
Publikováno v:
European Neuropsychopharmacology. 40:S204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d8fb6a46dccbecbd2fd64b7f5d32b94
https://doi.org/10.1016/j.euroneuro.2020.09.266
https://doi.org/10.1016/j.euroneuro.2020.09.266
Autor:
E. Toki, K. Terada, S. Goto, H. Yamakawa, K. Matsunaga, D. Watase, S. Setoguchi, J. Takata, Y. Karube
Publikováno v:
European Neuropsychopharmacology. 29:S219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecfb00450be8118112b9f277b2aac917
https://doi.org/10.1016/j.euroneuro.2019.09.327
https://doi.org/10.1016/j.euroneuro.2019.09.327
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Xinqun Zhang, Nicole M. Okeley, Scott C. Jeffrey, Patrick J. Burke, Stephen C. Alley, Peter D. Senter, Brian E. Toki
Publikováno v:
Bioconjugate Chemistry. 24:1650-1655
The role that carbohydrates play in antibody function and pharmacokinetics has made them important targets for modification. The terminal fucose of the N-linked glycan structure, which has been shown to be involved in modulation of antibody-directed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356dd35556713b5b98a69339cbd026f7
https://doi.org/10.1021/bc4002695
https://doi.org/10.1021/bc4002695