Dehydroepiandrosterone reduces expression and activity of BACE in NT2 neurons exposed to oxidative stress

Autor: E Tamagno, M Guglielmotto, P Bardini, G Santoro, A Davit, D Di Simone, O Danni, M Tabaton

Publikováno v: Neurobiology of Disease, Vol 14, Iss 2, Pp 291-301 (2003)

Recently, we showed that oxidative stress activates the expression and activity of the β-site AβPP-cleaving enzyme (BACE), an aspartyl protease responsible for the β-secretase cleavage of AβPP. The identification of compounds able to prevent the

Externí odkaz: https://doaj.org/article/b0ba842579aa45bca8f2083c0228567a

The molecular link between β- and γ-secretase activity on the amyloid β precursor protein

Autor: M. Tabaton, E. Tamagno

Publikováno v: Cellular and Molecular Life Sciences. 64:2211-2218

Alzheimer’s disease (AD) is characterized by an accumulation in the brain of amyloid β peptides (Aβ). The production of Aβ requires two sequential cleavages induced by β- and γ-secretases on the β-amyloid precursor protein (APP). Altered acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::984539c542fe0b304a02b4c9e7f10a94
https://doi.org/10.1007/s00018-007-7219-3

Consequences of Amyloid‐β Deficiency for the Liver.

Autor: Buniatian, Gayane Hrachia¹ (AUTHOR) buniatian@web.de, Schwinghammer, Ute¹ (AUTHOR), Tremmel, Roman^2,3 (AUTHOR), Cynis, Holger^4,5 (AUTHOR), Weiss, Thomas S.⁶ (AUTHOR), Weiskirchen, Ralf⁷ (AUTHOR), Lauschke, Volker M.^2,3,8 (AUTHOR), Youhanna, Sonia⁸ (AUTHOR), Ramos, Isbaal⁹ (AUTHOR), Valcarcel, Maria⁹ (AUTHOR), Seferyan, Torgom¹⁰ (AUTHOR), Rahfeld, Jens‐Ulrich⁴ (AUTHOR), Rieckmann, Vera⁴ (AUTHOR), Klein, Kathrin^2,3 (AUTHOR), Buadze, Marine¹ (AUTHOR), Weber, Victoria¹ (AUTHOR), Kolak, Valentina¹ (AUTHOR), Gebhardt, Rolf¹¹ (AUTHOR), Friedman, Scott L.¹² (AUTHOR), Müller, Ulrike C.¹³ (AUTHOR)

Publikováno v: Advanced Science. May2024, Vol. 11 Issue 18, p1-14. 14p.

Diversidad de insectos, colémbolos y arañas en viñedos bajo diferentes sistemas de producción, convencional y agroecológico, en Mendoza, Argentina.

Autor: Dagatti, Carla V.¹, Campón, Florencia Fernández¹, González, Marcela F.¹, Mazzitelli, María E.¹, Marcucci, Bruno¹

Publikováno v: Ecologia Austral. Apr2024, Vol. 34 Issue 1, p141-158. 18p.

Deep renovation methodology for 20th-century masterpieces: the case of Palazzo Affari by Carlo Mollino.

Autor: Di Renzo, Alessandro, Caneparo, Luca

Publikováno v: Renewable Energy & Environmental Sustainability; 2023, Vol. 8, p1-8, 8p