Zobrazeno 1 - 10 of 1 282 pro vyhledávání: '"E. Stuber"'
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Akademický článek
Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease
Autor: Luke R. Smart, Catherine I. Segbefia, Teresa S. Latham, Susan E. Stuber, Kwesi N. Amissah-Arthur, Klenam Dzefi-Tettey, Adam C. Lane, Yvonne A. Dei-Adomakoh, Russell E. Ware
Publikováno v: Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Haemoglobin SC (HbSC) is a common form of sickle cell disease (SCD), especially among individuals of West African ancestry. Persons with HbSC disease suffer from the same clinical complications and reduced quality of life that aff
Externí odkaz: https://doaj.org/article/b71b43d70ba9457abc2ae35766df103a
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3
Stroke Prevention with Hydroxyurea Enabled through Research and Education: A Phase 2 Primary Stroke Prevention Trial in Sub-Saharan Africa
Autor: Luke R. Smart, Emmanuela E. Ambrose, Georgina Balyorugulu, Primrose Songoro, Idd Shabani, Protas Komba, Mwesige Charles, Thad A. Howard, Kathryn E. McElhinney, Sara M. O’Hara, Jodie Odame, Maria Nakafeero, Janet Adams, Susan E. Stuber, Adam Lane, Teresa S. Latham, Abel N. Makubi, Russell E. Ware
Publikováno v: Acta Haematologica. 146:95-105
Introduction: Stroke is a severe complication of sickle cell anemia (SCA), with devastating sequelae. Transcranial Doppler (TCD) ultrasonography predicts stroke risk, but implementing TCD screening with suitable treatment for primary stroke preventio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dea3456e453ce26008443e5d56a4594
https://doi.org/10.1159/000526322
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Hydroxyurea is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa
Autor: Peter Olupot-Olupot, George Tomlinson, Thomas N. Williams, Léon Tshilolo, Brígida Santos, Luke R. Smart, Kathryn McElhinney, Thad A. Howard, Banu Aygun, Susan E. Stuber, Adam Lane, Teresa S. Latham, Russell E. Ware
Publikováno v: Blood.
Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) provides hydroxyurea at maximum tolerated dose (MTD) for children with sickle cell anemia (SCA) in sub-Saharan Africa. Beyond reducing SCA-related clinical events, docume
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5114c5896e01909f4f86eb51c6edf232
https://pubmed.ncbi.nlm.nih.gov/36375125
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Hydroxyurea reduces the transfusion burden in children with sickle cell anemia: the reach experience
Autor: Alexandra Power-Hays, George A. Tomlinson, Leon Tshilolo, Brigida Santos, Thomas N. Williams, Peter Olupot-Olupot, Patrick T. McGann, Banu Aygun, Adam Lane, Susan E. Stuber, Teresa Latham, Russell E. Ware
Publikováno v: American Society of Hematology Annual Scientifc conference
Introduction: Many children with sickle cell anemia (SCA) require blood transfusions, which carry risks and utilize a scarce resource globally, particularly in Africa. Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffae011d2bd52494469c08ea124c95ce
http://hdl.handle.net/10044/1/99893
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Building Capacity and Assessing Stroke Risk with Transcranial Doppler Ultrasonography in Sub-Saharan Africa: The Reach Experience
Autor: Maria Nakafeero, Russell E. Ware, Susan E. Stuber, Peter Olupot-Olupot, Patrick T. McGann, George Tomlinson, Léon Tshilolo, Janet Adams, Adam Lane, Brigida Santos, Banu Aygun, Thomas N. Williams, Teresa Latham
Publikováno v: Blood. 136:17-18
Introduction: Transcranial Doppler (TCD) screening data from Uganda, Tanzania, and Nigeria have documented elevated velocities in >20% of children with sickle cell anemia (SCA) not receiving hydroxyurea treatment. Realizing Effectiveness Across Conti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1650cb104fe0b13f202ad7d88e9a8c9d
https://doi.org/10.1182/blood-2020-142318
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9
Hydroxyurea to Reduce Stroke Risk in Tanzanian Children with Sickle Cell Anemia
Autor: Mwesige Charles, Susan E. Stuber, Adam Lane, Protas Komba, Russell E. Ware, Abel Nkono Makubi, Idd Shabani, Primrose Songoro, Luke R. Smart, Thad A. Howard, Emmanuela E. Ambrose, Teresa Latham
Publikováno v: Blood. 136:20-21
Introduction: Sickle cell anemia (SCA) is highly prevalent in sub-Saharan Africa with >300,000 annual births, and substantial morbidity and mortality due to limited resources. The burden of stroke in this population is of particular concern, given th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe23e9b48c4548dd83626ab99412f2a9
https://doi.org/10.1182/blood-2020-135944
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