Zobrazeno 1 - 10
of 166
pro vyhledávání: '"E. Stankiewicz"'
Autor:
Jessica R. Doll, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Jennifer L. Wayland, Adrienne Wilburn, Benjamin Weinhaus, Claire A. Chougnet, Daniela Giordano, Monica Cappelletti, Pietro Presicce, Suhas G. Kallapur, Nathan Salomonis, Tamara Tilburgs, Senad Divanovic
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112352- (2023)
Summary: Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF pro
Externí odkaz:
https://doaj.org/article/59d828a84fe34ca5847dca21b989426e
Autor:
Jarren R. Oates, Keisuke Sawada, Daniel A. Giles, Pablo C. Alarcon, Michelle S.M.A. Damen, Sara Szabo, Traci E. Stankiewicz, Maria E. Moreno-Fernandez, Senad Divanovic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInflammation is a common unifying factor in experimental models of non-alcoholic fatty liver disease (NAFLD) progression. Recent evidence suggests that housing temperature-driven alterations in hepatic inflammation correlate with exacerba
Externí odkaz:
https://doaj.org/article/1f1bb9be755e44ee861e3cade70d99e3
Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner
Autor:
Maria E. Moreno-Fernandez, Vishakha Sharma, Traci E. Stankiewicz, Jarren R. Oates, Jessica R. Doll, Michelle S. M. A. Damen, Maha A. T. A. Almanan, Claire A. Chougnet, David A. Hildeman, Senad Divanovic
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Background Understanding gender-associated bias in aging and obesity-driven metabolic derangements has been hindered by the inability to model severe obesity in female mice. Methods Here, using chow- or high fat diet (HFD)-feeding regimens a
Externí odkaz:
https://doaj.org/article/7d0c748d3a344ab1a14d117f2eb1e4a9
Autor:
Calvin C. Chan, Isaac T. W. Harley, Paul T. Pfluger, Aurelien Trompette, Traci E. Stankiewicz, Jessica L. Allen, Maria E. Moreno-Fernandez, Michelle S. M. A. Damen, Jarren R. Oates, Pablo C. Alarcon, Jessica R. Doll, Matthew J. Flick, Leah M. Flick, Joan Sanchez-Gurmaches, Rajib Mukherjee, Rebekah Karns, Michael Helmrath, Thomas H. Inge, Stuart P. Weisberg, Sünje J. Pamp, David A. Relman, Randy J. Seeley, Matthias H. Tschöp, Christopher L. Karp, Senad Divanovic
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar i
Externí odkaz:
https://doaj.org/article/1874a0fdf3df440c914731f67be8205d
Autor:
Calvin C. Chan, Michelle S. M. A. Damen, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Monica Cappelletti, Pablo C. Alarcon, Jarren R. Oates, Jessica R. Doll, Rajib Mukherjee, Xiaoting Chen, Rebekah Karns, Matthew T. Weirauch, Michael A. Helmrath, Thomas H. Inge, Senad Divanovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipoc
Externí odkaz:
https://doaj.org/article/d7769e000a41416a858c145b467956f7
Autor:
Monica Cappelletti, Jessica R. Doll, Traci E. Stankiewicz, Matthew J. Lawson, Vivien Sauer, Bingqiang Wen, Vladimir V. Kalinichenko, Xiaofei Sun, Tamara Tilburgs, Senad Divanovic
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
Infection-driven inflammation in pregnancy is a major cause of spontaneous preterm birth (PTB). Both systemic infection and bacterial ascension through the vagina/cervix to the amniotic cavity are strongly associated with PTB. However, the contributi
Externí odkaz:
https://doaj.org/article/bd2f0c1a6a2e41528ce78f3b2d2a01fe
Autor:
Daniel A. Giles, Bhama Ramkhelawon, Elizabeth M. Donelan, Traci E. Stankiewicz, Susan B. Hutchison, Rajib Mukherjee, Monica Cappelletti, Rebekah Karns, Christopher L. Karp, Kathryn J. Moore, Senad Divanovic
Publikováno v:
Molecular Metabolism, Vol 5, Iss 11, Pp 1121-1130 (2016)
Objectives: Obesity and obesity-associated inflammation is central to a variety of end-organ sequelae including atherosclerosis, a leading cause of death worldwide. Although mouse models have provided important insights into the immunopathogenesis of
Externí odkaz:
https://doaj.org/article/3a694425b8b14094874bf227efada484
Autor:
Lindsey-Romick Rosendale, Marie Dominique Filippi, Miki Watanabe-Chailland, Serena Liu, Kenjiro Shima, Brenna Carey, Rajesh K Kasam, Paritha Arumugam, M. Wessendarp, Claudia Chalk, Traci E. Stankiewicz, Y. Ma
Publikováno v:
Mitochondrion
Granulocyte-macrophage colony-stimulating factor (GM-CSF) exerts pleiotropic effects on macrophages and is required for self-renewal but the mechanisms responsible are unknown. Using mouse models with disrupted GM-CSF signaling, we show GM-CSF is cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d330846ded0cf079c33baed828cc90
https://doi.org/10.1016/j.mito.2021.10.009
https://doi.org/10.1016/j.mito.2021.10.009
Autor:
Se-Hyung Park, Michelle S M A Damen, Samir Softic, Senad Divanovic, De’Broski R. Herbert, Sara Szabo, Calvin C. Chan, Traci E. Stankiewicz, Jessica R Doll, Robert N. Helsley, Maria E. Moreno-Fernandez
Publikováno v:
International Journal of Obesity (2005)
ObjectiveThe risks of excess sugar intake in addition to high-fat diet consumption on immunopathogenesis of obesity-associated metabolic diseases are poorly defined. Interleukin-4 (IL-4) and IL-13 signaling via IL-4Rα regulates adipose tissue lipoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b224bcba79e770fcc5d4a636a95b0bf9
https://doi.org/10.1038/s41366-021-00902-6
https://doi.org/10.1038/s41366-021-00902-6