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Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort

Autor: Leonard B. Bacharier, Avraham Beigelman, Agustin Calatroni, Daniel J. Jackson, Peter J. Gergen, George T. O’Connor, Meyer Kattan, Robert A. Wood, Megan T. Sandel, Susan V. Lynch, Kei E. Fujimura, Douglas W. Fadrosh, Clark A. Santee, Homer Boushey, Cynthia M. Visness, James E. Gern, R. Wood, E. Matsui, H. Lederman, F. Witter, S. Leimenstoll, D. Scott, M. Cootauco, P. Jones, G. O’Connor, W. Cruikshank, M. Sandel, A. Lee-Parritz, C. Jordan, E. Gjerasi, P. Price-Johnson, L. Gagalis, L. Wang, N. Gonzalez, M. Tuzova, D. Gold, R. Wright, M. Kattan, C. Lamm, N. Whitney, P. Yaniv, M. Pierce, H. Sampson, R. Sperling, N. Rivers, G. Bloomberg, L. Bacharier, Y. Sadovsky, E. Tesson, C. Koerkenmeier, R. Sharp, K. Ray, J. Durrange, I. Bauer, A. Freie, V. Morgan. C. Visness, P. Zook, M. Yaeger, J. Martin, A. Calatroni, K. Jaffee, W. Taylor, R. Budrevich, H. Mitchell, W. Busse, J. Gern, P. Heinritz, C. Sorkness, K. Hernandez, Y. Bochkov, K. Grindle, A. Dresen, T. Pappas, M. Renneberg, B. Stoffel, P. Gergen, A. Togias, E. Smartt, K. Thompson

Publikováno v: American journal of respiratory and critical care medicine. 199(1)

Characterization of patterns of wheezing and allergic sensitization in early life may allow for identification of specific environmental exposures impacting asthma development.To define respiratory phenotypes in inner-city children and their associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122733aa74f1f95bd1af5066903ecdf6
https://pubmed.ncbi.nlm.nih.gov/30095995

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The Evolution of the Bacterial Luciferase Gene Cassette (lux) as a Real-Time Bioreporter

Autor: Dan Close, Sarah Price, Gary S. Sayler, Alexandra Rogers, Robert Crossley, Steven Ripp, Tingting Xu, Abby E. Smartt

Publikováno v: Sensors, Vol 12, Iss 1, Pp 732-752 (2012)
Sensors (Basel, Switzerland)

The bacterial luciferase gene cassette (lux) is unique among bioluminescent bioreporter systems due to its ability to synthesize and/or scavenge all of the substrate compounds required for its production of light. As a result, the lux system has the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf7adb0f0c7a2a996cd4d045f22c540
http://www.mdpi.com/1424-8220/12/1/732/

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Detection of Organic Compounds with Whole-Cell Bioluminescent Bioassays

Autor: Abby E. Smartt, Tingting Xu, Dan Close, Gary S. Sayler, Steven Ripp

Publikováno v: Bioluminescence: Fundamentals and Applications in Biotechnology-Volume 1 ISBN: 9783662433843

Natural and manmade organic chemicals are widely deposited across a diverse range of ecosystems including air, surface water, groundwater, wastewater, soil, sediment, and marine environments. Some organic compounds, despite their industrial values, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b082ddc7303898f8f589be04f001c70d
https://doi.org/10.1007/978-3-662-43385-0_4

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Expression of Non-Native Genes in a Surrogate Host Organism

Autor: Dan Close, Sarah Price, Gary S. Sayler, Abby E. Smartt, Steven Ripp, Tingting Xu

Publikováno v: Genetic Engineering-Basics, New Applications and Responsibilities

Genetic engineering can be utilized to improve the function of various metabolic and functional processes within an organism of interest. However, it is often the case that one wishes to endow a specific host organism with additional functionality an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890453481320257e74b0a014dbd6e8e5
http://www.intechopen.com/articles/show/title/expression-of-non-native-genes-in-a-surrogate-host-organism

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Comparison of fecal indicators with pathogenic bacteria and rotavirus in groundwater

Autor: Alexander van Geen, Abby E. Smartt, Talia Arbit, Michael Emch, Brian J. Mailloux, Gary S. Sayler, John Feighery, Patricia J. Culligan, Md. Jahangir Alam, Peter S.K. Knappett, Larry D. McKay, Alice C. Layton, Daniel E. Williams, P. Kim Streatfield, Veronica Escamilla, Ekaterina Alexandrova, Andrew Ferguson, Mohammad Yunus, Kazi Matin Ahmed

Groundwater is routinely analyzed for fecal indicators but direct comparisons of fecal indicators to the presence of bacterial and viral pathogens are rare. This study was conducted in rural Bangladesh where the human population density is high, sani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c35eb573d6fd8282ec95ebbd20da63

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Ameliorating Risk: Culturable and Metagenomic Monitoring of the 14 Year Decline of a Genetically Engineered Microorganism at a Bioremediation Field Site

Autor: Steven Ripp, Jana Phillips, Whitney Burton, Daniel E. Williams, Archana Chauhan, Alice C. Layton, Anthony V. Palumbo, Abby E. Smartt, Scott Moser, Gary S. Sayler

Publikováno v: Journal of Bioremediation & Biodegradation.

In 1996, the first EPA sanctioned release of a recombinant microbe (Pseudomonas fluorescens HK44) into the subsurface soil environment was initiated in a replicated semi-contained array of soil lysimeters. With an aim to access the survivability/envi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6347b1c4d1196880f41ccc467e03af06
https://doi.org/10.4172/2155-6199.s1-009

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Pathogen detection using engineered bacteriophages

Autor: Gary S. Sayler, Abby E. Smartt, Jessica J. Carswell, Patricia Jegier, Steven Ripp, Samuel A. Blount, Tingting Xu

Publikováno v: Analytical and bioanalytical chemistry. 402(10)

Bacteriophages, or phages, are bacterial viruses that can infect a broad or narrow range of host organisms. Knowing the host range of a phage allows it to be exploited in targeting various pathogens. Applying phages for the identification of microorg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6b1b1d5c64d4b27652c3c5dc84416f
https://pubmed.ncbi.nlm.nih.gov/22101465

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Bacteriophage reporter technology for sensing and detecting microbial targets

Autor: Steven Ripp, Abby E. Smartt

Publikováno v: Analytical and bioanalytical chemistry. 400(4)

Bacteriophages (phages) are bacterial viruses evolutionarily tuned to very specifically recognize, infect, and propagate within only a unique pool of host cells. Knowledge of these phage host ranges permits one to devise diagnostic tests based on pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0aebc9e35b3347850796ab769a7b6d5
https://pubmed.ncbi.nlm.nih.gov/21165607

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Draft Genome Sequence of the Polycyclic Aromatic Hydrocarbon-Degrading, Genetically Engineered Bioluminescent Bioreporter Pseudomonas fluorescens HK44

Autor: Alice C. Layton, Gary S. Sayler, Archana Chauhan, Daniel E. Williams, Steven Ripp, Abby E. Smartt, Steven D. Brown, Tatiana Karpinets

Publikováno v: Journal of Bacteriology. 193:5009-5010

Pseudomonas fluorescens strain HK44 (DSM 6700) is a genetically engineered lux -based bioluminescent bioreporter. Here we report the draft genome sequence of strain HK44. Annotation of ∼6.1 Mb of sequence indicates that 30% of the traits are unique

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47654558677fc4b2435daca30e2c3e44
https://doi.org/10.1128/jb.05530-11

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