Výsledky vyhledávání - "E. Shyam P Reddy"

Autor: Binu, Tharakan, Felicia A, Hunter, Saravanakumar, Muthusamy, Sonya, Randolph, Crystal, Byrd, Veena N, Rao, E Shyam P, Reddy, Ed W, Childs

Publikováno v: Shock. 57:309-315

ERG (ETS-related gene) is a member of the ETS (Erythroblast-transformation specific) family of transcription factors abundantly present in vascular endothelial cells. Recent studies demonstrate that ERG has important roles in blood vessel stability a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a609b0207c96c8c6e93e086dbb764e
https://doi.org/10.1097/shk.0000000000001899

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Mechanism Based Precision Diagnostics for BRCA1-Associated TNBC

Autor: Jingyao Xu, Alexis Clark, Yunlong Qin, Kristiana McLarty, Sothivin Lanh, Kirat Sandhu, Danita Eatman, Joel Okoli, E. Shyam P Reddy, Veena N Rao

BRCA1 gene mutations result in an increased risk for TNBC, which has a high mortality rate, and currently, there are no targeted therapies nor biomarkers for early detection. Various BRCA1 mutations have been found throughout the BRCA1 coding region;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::ea5520d6241144cc80e14ae98ee9f99d
https://zenodo.org/record/5710126

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Molecular Mechanism of β-Catenin Signaling Pathway Inactivation in ETV1-Positive Prostate Cancers

Autor: Shubhalaxmi Kayarthodi, Sampreet Reddy, Ed W. Childs, Sharif Morsalin, Roland Matthews, Chunshu Yang, Veena N. Rao, Jinbo Fang, E. Shyam P. Reddy

Publikováno v: Journal of Pharmaceutical Sciences and Pharmacology. 2:208-216

In the United States of America, prostate cancer is the second most common age-related cancer among men. African-American men have the highest incidence of, and mortality rate from this disease in the United States. According to the American Cancer S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34b17e592728db5dbcaddbc9b4cc53bb
https://doi.org/10.1166/jpsp.2015.1069

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A novel Ubc9 -dependent pathway regulates SIRT1- ER-α Axis and BRCA1-associated TNBC lung metastasis

Autor: Jingyao Xu, E. Shyam P. Reddy, Joel Okoli, Yonte Burnam, Victoria Lopez, Vaishali Reddy, Yulong Qin, Collin Shumate, Veena Rao

Triple negative breast cancer (TNBC) is a heterogeneous disease and has a higher rate of recurrence and distant metastasis. African-American (AA) women have a higher frequency of BRCA1 mutations and TNBC compared to other populations. Basal-like tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3409ffa79981ecb36285bbabd4579f3
https://europepmc.org/articles/PMC6655434/

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Autor: Veena Rao, Ujwala Gunnal, Chunshu Yang, Kunchala Rungsrisuriyachai, E. Shyam P. Reddy, Jinbo Fang, Brittany Mckenzie, Sharif Morsalin, Huali Xu, Shubhalaxmi Kayarthodi

Publikováno v: Journal of Pharmaceutical Sciences and Pharmacology. 1:175-181

TGF-β/Smads signaling plays a significant role in the regulation of growth of normal and prostate cancer cells. Smad proteins function as important mediators of intracellular signal transduction of transforming growth factor-β (TGF-β). TGF-β sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e583210a32387c6e255c3dd42a65a9
https://doi.org/10.1166/jpsp.2014.1022

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