Zobrazeno 1 - 10
of 459
pro vyhledávání: '"E. Selzer"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Previously, we reported that RhoA knockdown by morpholino antisense oligonucleotides (MOs), and enzymatic digestion of chondroitin sulfate proteoglycans (CSPGs) at the site of injury with chondroitinase ABC (ChABC), each can reduce retrograde neurona
Externí odkaz:
https://doaj.org/article/8ab27c06e866439facea1a3d62b1114a
Autor:
Nune Darbinian, Monica Hampe, Diana Martirosyan, Ahsun Bajwa, Armine Darbinyan, Nana Merabova, Gabriel Tatevosian, Laura Goetzl, Shohreh Amini, Michael E. Selzer
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5826 (2024)
Fetal alcohol spectrum disorders (FASDs) are leading causes of neurodevelopmental disability but cannot be diagnosed early in utero. Because several microRNAs (miRNAs) are implicated in other neurological and neurodevelopmental disorders, the effects
Externí odkaz:
https://doaj.org/article/73f32d55fad440c9a60448d4db521a50
Autor:
Nune Darbinian, Armine Darbinyan, Nana Merabova, Myrna Kassem, Gabriel Tatevosian, Shohreh Amini, Laura Goetzl, Michael E. Selzer
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionMitochondrial dysfunction is postulated to be a central event in fetal alcohol spectrum disorders (FASD). People with the most severe form of FASD, fetal alcohol syndrome (FAS) are estimated to live only 34 years (95% confidence interval,
Externí odkaz:
https://doaj.org/article/cd581b5194c84af399acf8a6b6b3268a
Autor:
Nune Darbinian, Gary L. Gallia, Armine Darbinyan, Ekaterina Vadachkoria, Nana Merabova, Amos Moore, Laura Goetzl, Shohreh Amini, Michael E. Selzer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13714 (2023)
Fetal alcohol spectrum disorders (FASD) are leading causes of neurodevelopmental disability. The mechanisms by which alcohol (EtOH) disrupts fetal brain development are incompletely understood, as are the genetic factors that modify individual vulner
Externí odkaz:
https://doaj.org/article/4ae5c3fbd19647939a8feff3e6c4dab2
Autor:
Nune Darbinian, Michael E Selzer
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 3, Pp 497-502 (2022)
The pathology of fetal alcohol syndrome and the less severe fetal alcohol spectrum disorders includes brain dysmyelination. Recent studies have shed light on the molecular mechanisms underlying these white matter abnormalities. Rodent models of fetal
Externí odkaz:
https://doaj.org/article/d8b5fe7afcd846d6bb6d7f7605fe8c77
Autor:
Guixin Zhang, Li-Qing Jin, William Rodemer, Jianli Hu, Zachary D. Root, Daniel M. Medeiros, Michael E. Selzer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Axon regrowth after spinal cord injury (SCI) is inhibited by several types of inhibitory extracellular molecules in the central nervous system (CNS), including chondroitin sulfate proteoglycans (CSPGs), which also are components of perineuronal nets
Externí odkaz:
https://doaj.org/article/9c41ccef149447e59f41956a4bce1fc4
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 6, Pp 996-1005 (2020)
Some neurons, especially in mammalian peripheral nervous system or in lower vertebrate or in vertebrate central nervous system (CNS) regenerate after axotomy, while most mammalian CNS neurons fail to regenerate. There is an emerging consensus that ne
Externí odkaz:
https://doaj.org/article/d059ea2e629c4b3eb8c956d9b8233626
Autor:
Nune Darbinian, Armine Darbinyan, John Sinard, Gabriel Tatevosian, Nana Merabova, Faith D’Amico, Tarek Khader, Ahsun Bajwa, Diana Martirosyan, Alina K. Gawlinski, Richa Pursnani, Huaqing Zhao, Shohreh Amini, Mary Morrison, Laura Goetzl, Michael E. Selzer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 135 (2022)
Prenatal alcohol exposure can cause developmental abnormalities (fetal alcohol spectrum disorders; FASD), including small eyes, face and brain, and neurobehavioral deficits. These cannot be detected early in pregnancy with available imaging technique
Externí odkaz:
https://doaj.org/article/b34a4288d3dc4e1494824e112b1867b3
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1955-1956 (2022)
Externí odkaz:
https://doaj.org/article/cc37e70756734695ae6545ad34df4ffb
Autor:
William Rodemer, Michael E. Selzer
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 399-404 (2019)
Spinal cord injury leads to persistent behavioral deficits because mammalian central nervous system axons fail to regenerate. A neuron’s response to axon injury results from a complex interplay of neuron-intrinsic and environmental factors. The con
Externí odkaz:
https://doaj.org/article/11e3a83dde644baeb37521fb66315612