Zobrazeno 1 - 10
of 169
pro vyhledávání: '"E. Seemann"'
Autor:
Kristina Pavlovic, MDolores Carmona-Luque, Giulia I. Corsi, Noelia Maldonado-Pérez, Francisco J. Molina-Estevez, Esther Peralbo-Santaella, Marina Cortijo-Gutiérrez, Pedro Justicia-Lirio, María Tristán-Manzano, Víctor Ronco-Díaz, Antonio Ballesteros-Ribelles, Alejandro Millán-López, Paula Heredia-Velázquez, Carla Fuster-García, Toni Cathomen, Stefan E. Seemann, Jan Gorodkin, Francisco Martin, Concha Herrera, Karim Benabdellah
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChimeric antigen receptor-expressing T cells (CAR T cells) have revolutionized cancer treatment, particularly in B cell malignancies. However, the use of autologous T cells for CAR T therapy presents several limitations, including high co
Externí odkaz:
https://doaj.org/article/ba7d41b073e14a1ba7378cf787091c51
Autor:
Alessia Cavazza, Ayal Hendel, Rasmus O. Bak, Paula Rio, Marc Güell, Duško Lainšček, Virginia Arechavala-Gomeza, Ling Peng, Fatma Zehra Hapil, Joshua Harvey, Francisco G. Ortega, Coral Gonzalez-Martinez, Carsten W. Lederer, Kasper Mikkelsen, Giedrius Gasiunas, Nechama Kalter, Manuel A.F.V. Gonçalves, Julie Petersen, Alejandro Garanto, Lluis Montoliu, Marcello Maresca, Stefan E. Seemann, Jan Gorodkin, Loubna Mazini, Rosario Sanchez, Juan R. Rodriguez-Madoz, Noelia Maldonado-Pérez, Torella Laura, Michael Schmueck-Henneresse, Cristina Maccalli, Julian Grünewald, Gloria Carmona, Neli Kachamakova-Trojanowska, Annarita Miccio, Francisco Martin, Giandomenico Turchiano, Toni Cathomen, Yonglun Luo, Shengdar Q. Tsai, Karim Benabdellah
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102066- (2023)
The European Cooperation in Science and Technology (COST) is an intergovernmental organization dedicated to funding and coordinating scientific and technological research in Europe, fostering collaboration among researchers and institutions across co
Externí odkaz:
https://doaj.org/article/dff3b1dde38845db9319c7538193d46c
Autor:
Giulia I. Corsi, Veerendra P. Gadekar, Henriette Haukedal, Nadezhda T. Doncheva, Christian Anthon, Sheetal Ambardar, Dasaradhi Palakodeti, Poul Hyttel, Kristine Freude, Stefan E. Seemann, Jan Gorodkin
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 105980- (2023)
Alzheimer's disease (AD) is a progressive and irreversible brain disorder, which can occur either sporadically, due to a complex combination of environmental, genetic, and epigenetic factors, or because of rare genetic variants in specific genes (fam
Externí odkaz:
https://doaj.org/article/ee81fe4b9b794196a8c7ff4609458c32
Autor:
Adrian S. Geissler, Line D. Poulsen, Nadezhda T. Doncheva, Christian Anthon, Stefan E. Seemann, Enrique González-Tortuero, Anne Breüner, Lars J. Jensen, Carsten Hjort, Jeppe Vinther, Jan Gorodkin
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The production of the alpha-amylase (AMY) enzyme in Bacillus subtilis at a high rate leads to the accumulation of unfolded AMY, which causes secretion stress. The over-expression of the PrsA chaperone aids enzyme folding and reduces stress. To identi
Externí odkaz:
https://doaj.org/article/a60d2c584eda4fc5adb17a7740bf7e63
Autor:
Tobias Bergmann, Yong Liu, Jonathan Skov, Leo Mogus, Julie Lee, Ulrich Pfisterer, Louis-Francois Handfield, Andrea Asenjo-Martinez, Irene Lisa-Vargas, Stefan E. Seemann, Jimmy Tsz Hang Lee, Nikolaos Patikas, Birgitte Rahbek Kornum, Mark Denham, Poul Hyttel, Menno P. Witter, Jan Gorodkin, Tune H. Pers, Martin Hemberg, Konstantin Khodosevich, Vanessa Jane Hall
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Stellate cells are principal neurons in the entorhinal cortex that contribute to spatial processing. They also play a role in the context of Alzheimer’s disease as they accumulate Amyloid beta early in the disease. Producing human stellate cells fr
Externí odkaz:
https://doaj.org/article/33496e16dde243a0a9478f786050d0ba
Autor:
Signe E. Cremer, James L. Catalfamo, Robert Goggs, Stefan E. Seemann, Annemarie T. Kristensen, Paulina B. Szklanna, Patricia B. Maguire, Marjory B. Brooks
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 55-68 (2021)
Abstract Background Domestic dogs represent a translational animal model to study naturally occurring human disease. Proteomics has emerged as a promising tool for characterizing human platelet pathophysiology; thus a detailed characterization of the
Externí odkaz:
https://doaj.org/article/14310a91d0e74aff9e4e5f25ab057422
Autor:
Jacopo Vegni, Ying Sun, Stefan E. Seemann, Martina Zappaterra, Roberta Davoli, Stefania Dall’Olio, Jan Gorodkin, Paolo Zambonelli
Publikováno v:
Animals, Vol 13, Iss 7, p 1187 (2023)
The addition of n-3 polyunsaturated fatty acids (n-3 PUFAs) to the swine diet increases their content in muscle cells, and the additional supplementation of antioxidants promotes their oxidative stability. However, to date, the functionality of these
Externí odkaz:
https://doaj.org/article/3aa4ea78f5134721b7a0c450e5bc0161
Autor:
Yong Liu, Tobias Bergmann, Yuki Mori, Juan Miguel Peralvo Vidal, Maria Pihl, Navneet A. Vasistha, Preben Dybdahl Thomsen, Stefan E. Seemann, Jan Gorodkin, Poul Hyttel, Konstantin Khodosevich, Menno P. Witter, Vanessa Jane Hall
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
The entorhinal cortex (EC) is the spatial processing center of the brain and structurally is an interface between the three layered paleocortex and six layered neocortex, known as the periarchicortex. Limited studies indicate peculiarities in the for
Externí odkaz:
https://doaj.org/article/746fcf2ebe194ca39fff7002aae87ad9
Autor:
Rebecca Kirsch, Stefan E. Seemann, Walter L. Ruzzo, Stephen M. Cohen, Peter F. Stadler, Jan Gorodkin
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
Abstract Background Comparative genomics approaches have facilitated the discovery of many novel non-coding and structured RNAs (ncRNAs). The increasing availability of related genomes now makes it possible to systematically search for compensatory b
Externí odkaz:
https://doaj.org/article/75f8db5f6b8744789323b3607767dd10
Autor:
Josephine Skat-Rørdam, David H. Ipsen, Stefan E. Seemann, Markus Latta, Jens Lykkesfeldt, Pernille Tveden-Nyborg
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1198 (2021)
The successful development of effective treatments against nonalcoholic steatohepatitis (NASH) is significantly set back by the limited availability of predictive preclinical models, thereby delaying and reducing patient recovery. Uniquely, the guine
Externí odkaz:
https://doaj.org/article/c56d9914579c4057b728b4b8af90d4ef