Zobrazeno 1 - 10
of 69
pro vyhledávání: '"E. Schreurs"'
Autor:
Renée R. C. E. Schreurs, Athanasios Koulis, Thijs Booiman, Brigitte Boeser-Nunnink, Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Neeltje A. Kootstra, Carla M. S. Ribeiro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic HIV-1 infection is characterized by T-cell dysregulation that is partly restored by antiretroviral therapy. Autophagy is a critical regulator of T-cell function. Here, we demonstrate a protective role for autophagy in HIV-1 disease p
Externí odkaz:
https://doaj.org/article/3c90dc6926bc447289817ab4859f4bfc
Autor:
Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Tracy-Jane T. H. D. Eisden, Sterre van Piggelen, Renée R. C. E. Schreurs, Carla M. S. Ribeiro
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dengue virus (DENV), transmitted by infected mosquitoes, is a major public health concern, with approximately half the world’s population at risk for infection. Recent decades have increasing incidence of dengue-associated disease alongside growing
Externí odkaz:
https://doaj.org/article/fbf2b04da0c241539e9d494b0648c9d1
Autor:
Sarah-May M. L. The, Renée R. C. E. Schreurs, Agata Drewniak, Roel Bakx, Tim G. J. de Meij, Andries E. Budding, Linda Poort, Huib A. Cense, Hugo A. Heij, L. W. Ernest van Heurn, Ramon R. Gorter, Madeleine J. Bunders
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionAppendicitis is one of the most common causes of acute abdominal surgery in children. The clinical course of appendicitis ranges from simple to complex appendicitis. The mechanisms underlying the heterogeneity of appendicitis in children
Externí odkaz:
https://doaj.org/article/f4f903d5761047e7af6828841d9c19af
Autor:
Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Jimena Pérez-Vargas, Connor A. H. Thompson, Siobhan Ennis, Masahiro Niikura, Manon E. Wildenberg, Vanesa Muncan, Renée R. C. E. Schreurs, François Jean, Carla M. S. Ribeiro
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTSARS-CoV-2, the causative virus of COVID-19, continues to threaten global public health. COVID-19 is a multi-organ disease, causing not only respiratory distress, but also extrapulmonary manifestations, including gastrointestinal symptoms wit
Externí odkaz:
https://doaj.org/article/20a7f625903a4849b595ebef82383493
Autor:
Alexandra P. M. Cloherty, Nienke H. van Teijlingen, Tracy-Jane T. H. D. Eisden, John L. van Hamme, Anusca G. Rader, Teunis B. H. Geijtenbeek, Renée R. C. E. Schreurs, Carla M. S. Ribeiro
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication. However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 persists in long-lived tissue-derived dendritic cells (DCs)
Externí odkaz:
https://doaj.org/article/747ad914bf0d46c9860d30f8766e3ccd
Autor:
Adrian F. Sagebiel, Fenja Steinert, Sebastian Lunemann, Christian Körner, Renée R. C. E. Schreurs, Marcus Altfeld, Daniel Perez, Konrad Reinshagen, Madeleine J. Bunders
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by
Externí odkaz:
https://doaj.org/article/df407d747ae34b6e86a1aa8b20d600bd
Autor:
Ana, Jordan-Paiz, Glòria, Martrus, Fenja L, Steinert, Max, Kaufmann, Adrian F, Sagebiel, Renée R C E, Schreurs, Anne, Rechtien, Martin E, Baumdick, Johannes M, Jung, Kimberly J, Möller, Lucy, Wegner, Cordula, Grüttner, Laura, Richert, Roland, Thünauer, Jennifer, Schroeder-Schwarz, Johannes B, van Goudoever, Teunis B H, Geijtenbeek, Marcus, Altfeld, Steven T, Pals, Daniel, Perez, Paul L, Klarenbeek, Christian, Tomuschat, Guido, Sauter, Ingo, Königs, Udo, Schumacher, Manuel A, Friese, Nathaniel, Melling, Konrad, Reinshagen, Madeleine J, Bunders
Publikováno v:
Cellularmolecular immunology.
Gastrointestinal infections are a major cause for serious clinical complications in infants. The induction of antibody responses by B cells is critical for protective immunity against infections and requires CXCR5
Autor:
Carla M. S. Ribeiro, Roel Bakx, A. J. Highton, J.B. van Goudoever, Adrian F. Sagebiel, R. R. C. E. Schreurs, Paul L. Klarenbeek, Fenja L Steinert, M. J. Bunders, Teunis B. H. Geijtenbeek, Daniel Perez, Agata Drewniak, Konrad Reinshagen
Publikováno v:
Schreurs, R R C E, Sagebiel, A F, Steinert, F L, Highton, A J, Klarenbeek, P L, Drewniak, A, Bakx, R, The, S M L, Ribeiro, C M S, Perez, D, Reinshagen, K, Geijtenbeek, T B H, van Goudoever, J B & Bunders, M J 2021, ' Intestinal CD8+ T cell responses are abundantly induced early in human development but show impaired cytotoxic effector capacities ', Mucosal Immunology, vol. 14, no. 3, pp. 605-614 . https://doi.org/10.1038/s41385-021-00382-x
Mucosal Immunology, 14(3), 605-614. Nature Publishing Group
Mucosal immunology, 14(3), 605-614. Nature Publishing Group
Mucosal Immunology, 14(3), 605-614. Nature Publishing Group
Mucosal immunology, 14(3), 605-614. Nature Publishing Group
Gastrointestinal viral infections are a major global cause of disease and mortality in infants. Cytotoxic CD8+ T cells are critical to achieve viral control. However, studies investigating the development of CD8+ T cell immunity in human tissues earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bba5d833fd8f5328e42d5761035dec
https://research.vumc.nl/en/publications/a7222ddc-580e-48d3-be1f-f93713596153
https://research.vumc.nl/en/publications/a7222ddc-580e-48d3-be1f-f93713596153
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 2, Pp 100519-(2021)
STAR Protocols, 2(2):100519. Cell Press
STAR Protocols, Vol 2, Iss 2, Pp 100519-(2021)
STAR Protocols, 2(2):100519. Cell Press
Summary Crosstalk between immune cells and intestinal stem cells (ISCs) in vivo plays a critical role in tissue homeostasis and inflammation; however, in vitro models based on primary cells recapitulating this interaction were lacking. Here, we provi
Autor:
Teunis B. H. Geijtenbeek, John L. van Hamme, Tracy-Jane T. H. D. Eisden, Renée R. C. E. Schreurs, Carla M. S. Ribeiro, Anusca G. Rader, Alexandra P. M. Cloherty, Nienke H. van Teijlingen
Publikováno v:
Scientific Reports
Scientific reports, 11(1):4767. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific reports, 11(1):4767. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication. However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 persists in long-lived tissue-derived dendritic cells (DCs) and CD4+