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Akademický článek

Systematic review of reporting benefits and harms of surgical interventions in randomized clinical trials

Autor: F. E. Stubenrouch, E. S. Cohen, P. M. M. Bossuyt, M. J. W. Koelemay, P. C. R. van der Vet, D. T. Ubbink

Publikováno v: BJS Open, Vol 4, Iss 2, Pp 171-181 (2020)

Background Standardized reporting methods facilitate comparisons between studies. Reporting of data on benefits and harms of treatments in surgical RCTs should support clinical decision‐making. Correct and complete reporting of the outcomes of clin

Externí odkaz: https://doaj.org/article/b1254274e64c43f0afb64473dbce09fd

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Systematic review of reporting benefits and harms of surgical interventions in randomized clinical trials

Autor: Patrick M.M. Bossuyt, P C R van der Vet, Fabienne E. Stubenrouch, E S Cohen, Dirk T. Ubbink, Mark J.W. Koelemay

Publikováno v: BJS Open
BJS Open, Vol 4, Iss 2, Pp 171-181 (2020)
Stubenrouch, F E, Cohen, E S, Bossuyt, P M M, Koelemay, M J W, van der Vet, P C R & Ubbink, D T 2020, ' Systematic review of reporting benefits and harms of surgical interventions in randomized clinical trials ', BJS open, vol. 4, no. 2, pp. 171-181 . https://doi.org/10.1002/bjs5.50240
BJS open, 4(2), 171-181. John Wiley & Sons Ltd.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbc837e03089c0ac506f7cdb0a77718
https://doi.org/10.1002/bjs5.50240

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Sputum biomarkers during acute severe asthma attacks in children-a case-control study

Autor: E. S. Cohen, Manisha Ramphul, Erol A. Gaillard, W Monteiro, Richard D. May, Kathryn G Welsh, Michael A Ghebre, Karine Rousseau, Laura Rapley, David J. Thornton, Athula Herath, Christopher E. Brightling

Publikováno v: Acta paediatrica (Oslo, Norway : 1992)REFERENCES. 111(3)

AIM To study sputum mediator profiles pattern in children with acute severe asthma, compared with stable asthma and healthy controls. The mechanisms of acute severe asthma attacks, such as biomarkers cascades and immunological responses, are poorly u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc3154c0c7b7d8762a189495f3dfd1d
https://pubmed.ncbi.nlm.nih.gov/34773288

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Sputum microbiomic clustering in asthma and chronic obstructive pulmonary disease reveals a Haemophilus ‐predominant subgroup

Autor: Laura Rapley, Richard D. May, Paul Newbold, Ian D. Pavord, Koirobi Haldar, Michael A Ghebre, Mona Bafadhel, Sarah Diver, Dhananjay Desai, Paul Rugman, Michael R. Barer, Christopher E. Brightling, Matthew Richardson, Mohammadali Yavari Ramsheh, E. S. Cohen

Publikováno v: Allergy

Background Airway ecology is altered in asthma and chronic obstructive pulmonary disease (COPD). Anti‐microbial interventions might have benefit in subgroups of airway disease. Differences in sputum microbial profiles at acute exacerbation of airwa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16bd5a20ef753f6e1f6f8064b1dbe7f
https://doi.org/10.1111/all.14058

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Preclinical development of CAT-354, an IL-13 neutralizing antibody, for the treatment of severe uncontrolled asthma

Autor: Dominic J. Corkill, F Koentgen, E C Martin, J Powell, L A Conroy, Nicola H.E. Davis, Joanne Woods, E. S. Cohen, Phillip Monk, N Brennan, Alison J. Dodd, R. M. Wilson, D Manuel, C Joberty-Candotti, F Dempsey, I.K. Anderson, Richard D. May

Publikováno v: British Journal of Pharmacology. 166:177-193

BACKGROUND AND PURPOSE IL-13 is a pleiotropic Th2 cytokine considered likely to play a pivotal role in asthma. Here we describe the preclinical in vitro and in vivo characterization of CAT-354, an IL-13-neutralizing IgG4 monoclonal antibody (mAb), cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96d66ac00a4592a4a548a0f9e1bf51ec
https://doi.org/10.1111/j.1476-5381.2011.01659.x

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A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke

Autor: Matthew A. Sleeman, A J Coyle, I K Anderson, Roland Kolbeck, Fernando M. Botelho, Martin R. Stämpfli, E S Cohen, N H E Davis, A A Humbles, James K. Nikota, Carla M. T. Bauer

Publikováno v: European Respiratory Journal. 38:285-294

We investigated the role of granulocyte-macrophage colony-stimulating factor (GM-CSF) in a subchronic exposure model of cigarette smoke (CS)-induced inflammation using antibodies directed against GM-CSF or the GM-CSF receptor (GM-CSFR) α-chain. CS-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02acc6ba71907ee0c8ae1f9716d4bc3a
https://doi.org/10.1183/09031936.00076210

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