Zobrazeno 1 - 10
of 1 059
pro vyhledávání: '"E. Rudd"'
Autor:
Thai Hien Tu, Ami Grunbaum, François Santinon, Alexandra Kazanova, Nicholas Rozza, Richard Kremer, Catalin Mihalcioiu, Christopher E. Rudd
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract COVID-19, caused by SARS-CoV-2, can lead to a severe inflammatory disease characterized by significant lymphopenia. However, the underlying cause for the depletion of T-cells in COVID-19 patients remains incompletely understood. In this stud
Externí odkaz:
https://doaj.org/article/f893adaa54fc42cb8cdbad8e742eed76
Autor:
H. Sio, A. Krygier, D. G. Braun, R. E. Rudd, S. A. Bonev, F. Coppari, M. Millot, D. E. Fratanduono, N. Bhandarkar, M. Bitter, D. K. Bradley, P. C. Efthimion, J. H. Eggert, L. Gao, K. W. Hill, R. Hood, W. Hsing, N. Izumi, G. Kemp, B. Kozioziemski, O. L. Landen, K. Le Galloudec, T. E. Lockard, A. Mackinnon, J. M. McNaney, N. Ose, H.-S. Park, B. A. Remington, M. B. Schneider, S. Stoupin, D. B. Thorn, S. Vonhof, C. J. Wu, Y. Ping
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Large laser facilities have recently enabled material characterization at the pressures of Earth and Super-Earth cores. However, the temperature of the compressed materials has been largely unknown, or solely relied on models and simulations
Externí odkaz:
https://doaj.org/article/258382f7cab343e8ac2471967b385953
Autor:
Alejandro Munoz-Valencia, Jackline O. Aridi, Linda S. Barnes, Kristina E. Rudd, Bopaya Bidanda, Tonny Epuu, Robert Kamu, Tecla Kivuli, Jana Macleod, Cindy M. Makanga, Jennifer Makin, Muthoni Mate, Carolyne Njoki Muiru, Gatwiri Murithi, Abdirahaman Musa, Hellen Nyagol, Kevin Ochieng, Jayant Rajgopal, Nakul P. Raykar, Yiqi Tian, Mark H. Yazer, Bo Zeng, Bernard Olayo, Pratap Kumar, Juan Carlos Puyana
Publikováno v:
BMC Health Services Research, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Safe blood is essential for the care of patients with life-threatening anemia and hemorrhage. Low blood donation rates, inefficient testing procedures, and other supply chain disruptions in blood administration affect patients in
Externí odkaz:
https://doaj.org/article/9df1ba8a814b4ce8a532306eb0b5fa04
Autor:
Silvia Guil-Luna, Aurora Rivas-Crespo, Carmen Navarrete-Sirvent, Ana Mantrana, Alejandra Pera, Rafael Mena-Osuna, Marta Toledano-Fonseca, María Victoria García-Ortíz, Carlos Villar, Maria Teresa Sánchez-Montero, Janna Krueger, Francisco Javier Medina-Fernández, Juan De La Haba-Rodríguez, Auxiliadora Gómez-España, Enrique Aranda, Christopher E. Rudd, Antonio Rodríguez-Ariza
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115592- (2023)
Introduction: Glycogen synthase kinase 3 (GSK-3) has been proposed as a novel cancer target due to its regulating role in both tumor and immune cells. However, the connection between GSK-3 and immunoevasive contexture, including tumor budding (TB) ha
Externí odkaz:
https://doaj.org/article/77ecc79605674de6b8a6c57e14222455
Autor:
François Santinon, Bennani Fatima Ezzahra, Meriem Bachais, Alain Sarabia Pacis, Christopher E. Rudd
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract PD-1 immune checkpoint blockade against inhibitory receptors such as receptor programmed cell death-1 (PD-1), has revolutionized cancer treatment. Effective immune reactivity against tumour antigens requires the infiltration and activation o
Externí odkaz:
https://doaj.org/article/9ff18432cb50407a81c7520ea490f4ce
Autor:
Fatima Ezzahra Bennani, Khalid Karrouchi, Latifa Doudach, Mario Scrima, Noor Rahman, Luca Rastrelli, Trina Ekawati Tallei, Christopher E. Rudd, My El Abbes Faouzi, M’hammed Ansar
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5312-5351 (2022)
Despite continual efforts being made with multiple clinical studies and deploying cutting-edge diagnostic tools and technologies, the discovery of new cancer therapies remains of severe worldwide concern. Multiple drug resistance has also emerged in
Externí odkaz:
https://doaj.org/article/6e1daa3dfa014fd2ab03d3109669e8a1
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T-cell activation is a complex process involving a network of kinases and downstream molecular scaffolds or adaptors that integrate surface signals with effector functions. One key immune-specific adaptor is Src kinase-associated phosphoprotein 1 (SK
Externí odkaz:
https://doaj.org/article/4e98e2eee1b1411f841d15412e47181c
Autor:
Kathryn S. Tomsho, Erin Polka, Stacey Chacker, David Queeley, Marty Alvarez, Madeleine K. Scammell, Karen M. Emmons, Rima E. Rudd, Gary Adamkiewicz
Publikováno v:
Environmental Health, Vol 21, Iss 1, Pp 1-12 (2022)
Abstract Background Although there is increasing interest in reporting results of environmental research efforts back to participants, evidence-based tools have not yet been applied to developed materials to ensure their accessibility in terms of lit
Externí odkaz:
https://doaj.org/article/4faafa358c0f4d468308fca0178d5dc1
Autor:
B. Jason Brotherton, Mugdha Joshi, George Otieno, Sarah Wandia, Hannah Gitura, Ariel Mueller, Tony Nguyen, Steve Letchford, Elisabeth D. Riviello, Evelyn Karanja, Kristina E. Rudd
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
ImportanceMortality prediction among critically ill patients in resource limited settings is difficult. Identifying the best mortality prediction tool is important for counseling patients and families, benchmarking quality improvement efforts, and de
Externí odkaz:
https://doaj.org/article/05432a5432e74696b5a931a6c159da25
Autor:
Christian Wichmann, Sagun Parakh, Gerard G Hanna, Thomas John, Jason Callahan, Benjamin Blyth, Michael MacManus, Daniel Steinfort, Andrew M Scott, Lisa Devereux, Fiona Hegi-Johnson, Stacey E Rudd, Tim Akhurst, Peter Roselt, Jenny Trinh, Paul S Donnelly, Rod Hicks, Stephen Fox, Kate Burbury
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Background ImmunoPET is a multicentre, single arm, phase 0–1 study that aims to establish if 89Zr-durvalumab PET/CT can be used to interrogate the expression of PD-L1 in larger, multicentre clinical trials.Methods The phase 0 study recruited 5 PD-L
Externí odkaz:
https://doaj.org/article/3ec7e11a980b4b738c6b1a546c955538