Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

Autor: E. Royo-Rubio, I. Rodríguez-Izquierdo, M. Moreno-Domene, T. Lozano-Cruz, F. J. de la Mata, R. Gómez, M. A. Muñoz-Fernández, J. L. Jiménez

Publikováno v: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-16 (2021)

Abstract Background The appearance of resistance against new treatments and the fact that HIV-1 can infect various cell types and develop reservoirs and sanctuaries makes it necessary to develop new therapeutic approaches to overcome those failures.

Externí odkaz: https://doaj.org/article/d3ce05c02cae48f7a8952e69bde1393c

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Cationic Carbosilane Dendrimers for Apmnkq2 Aptamer Transfection in Breast Cancer: An Alternative to Traditional Transfectants.

Autor: Madrid L; Universidad de Alcalá, Department of Organic and Inorganic Chemistry, Research Institute in Chemistry 'Andrés M. del Río' (IQAR), Chamartín, Madrid, 28805, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, 28029, Spain., Pinto-Díez C; Aptus Biotech SL, Fuencarral-El Pardo, Madrid, 28035, Spain., Muñoz-Moreno L; Universidad de Alcalá, Department of Biology of Systems, Biochemistry and Molecular Biology Unit, Madrid, Madrid, 28805, Spain., García-Hernández M; Grupo de Aptámeros, Departamento de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Fuencarral-El Pardo, Madrid, 28034, Spain.; Institute 'Ramón y Cajal' for Health Research (IRYCIS), Fuencarral-El Pardo, Madrid, 28034, Spain., González VM; Grupo de Aptámeros, Departamento de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Fuencarral-El Pardo, Madrid, 28034, Spain.; Institute 'Ramón y Cajal' for Health Research (IRYCIS), Fuencarral-El Pardo, Madrid, 28034, Spain., Mata J; Universidad de Alcalá, Department of Organic and Inorganic Chemistry, Research Institute in Chemistry 'Andrés M. del Río' (IQAR), Chamartín, Madrid, 28805, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, 28029, Spain.; Institute 'Ramón y Cajal' for Health Research (IRYCIS), Fuencarral-El Pardo, Madrid, 28034, Spain., Martin ME; Grupo de Aptámeros, Departamento de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Fuencarral-El Pardo, Madrid, 28034, Spain.; Institute 'Ramón y Cajal' for Health Research (IRYCIS), Fuencarral-El Pardo, Madrid, 28034, Spain., Ortega P; Universidad de Alcalá, Department of Organic and Inorganic Chemistry, Research Institute in Chemistry 'Andrés M. del Río' (IQAR), Chamartín, Madrid, 28805, Spain.; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, 28029, Spain.; Institute 'Ramón y Cajal' for Health Research (IRYCIS), Fuencarral-El Pardo, Madrid, 28034, Spain.

Publikováno v: Macromolecular bioscience [Macromol Biosci] 2024 Oct 14, pp. e2400327. Date of Electronic Publication: 2024 Oct 14.

Transition Metal-containing Dendrimers in Biomedicine : Current Trends

Autor: Alaa S Abd-El-Aziz, Amal M Youssef, Ahmad Abd-El-Aziz

There has been increasing research into designing transition metal-containing dendrimers as innovative materials, especially in the field of biomedicine and pharmaceutical science. They have applications in biosensors and drug-delivery systems, and a