Zobrazeno 1 - 10
of 52
pro vyhledávání: '"E. Rossomacha"'
Autor:
J.S. Rockel, A. Maglaviceanu, H. Fetter Filippini, E. Wasilewski, M.M. Lewis-Bakker, S. Gabrial, E. Rossomacha, J. Garcia, T. Leroux, H. Clarke, R.P. Bonin, L.P. Kotra, M. Kapoor
Publikováno v:
Osteoarthritis and Cartilage. 31:S218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::283a6a49b95eb8f489ec3bb91e89394d
https://doi.org/10.1016/j.joca.2023.01.200
https://doi.org/10.1016/j.joca.2023.01.200
Autor:
Mohit Kapoor, K. Shestopaloff, Anirudh Sharma, Nizar N. Mahomed, G. Tavallaee, E. Rossomacha, Helal Endisha, S. Nakamura, Poulami Datta, Shabana Amanda Ali, P. Potla, Starlee Lively, Carolen Younan, Rajiv Gandhi, Jason S. Rockel, Igor Jurisica, Roman Krawetz
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Objective MicroRNA‐34a‐5p (miR‐34a‐5p) expression is elevated in the synovial fluid of patients with late‐stage knee osteoarthritis (OA); however, its exact role and therapeutic potential in OA remain to be fully elucidated. This study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1826a92111fc2847e44af70cb89d3632
https://doi.org/10.1002/art.41552
https://doi.org/10.1002/art.41552
Autor:
E. Rossomacha, Rajiv Gandhi, Brian Wu, Osvaldo Espin-Garcia, S. Nakamura, Jason S. Rockel, Mohit Kapoor
Publikováno v:
Osteoarthritis and Cartilage. 28:1394-1400
Summary Object Autophagy maintains cartilage homeostasis and is compromised during osteoarthritis (OA), contributing to cartilage degeneration. We sought to determine if D-isomer TAT-Beclin-1, a potent inducer of autophagy, could attenuate post-traum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dec209bd6add3829ab9cec6ff344b7a
https://doi.org/10.1016/j.joca.2020.07.001
https://doi.org/10.1016/j.joca.2020.07.001
Autor:
Robert D. Inman, Shaghayegh Foroozan Boroojeni, Rohan Machhar, Ye-Soo Park, Kyle T. Reid, Igor Jurisica, E. Rossomacha, Tae-Hwan Kim, Masaki Kusuda, Brian Wu, Nigil Haroon, Richard Bucala, S. Nakamura, Sungsin Jo, Jason S. Rockel, Melissa Lim, Fanxing Zeng, Sarah Q. Crome, Akihiro Nakamura, Mohit Kapoor, Eric Gracey, Francesco Ciccia, Lin Leng
Publikováno v:
Science translational medicine. 13(616)
Spondyloarthritis (SpA), a type 3 immunity-mediated inflammatory arthritis, is a systemic rheumatic disease that primarily affects the joints, spine, gut, skin, and eyes. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3a0f2e8be7fe3a45a4070f0e19b4dc
https://pubmed.ncbi.nlm.nih.gov/34851696
https://pubmed.ncbi.nlm.nih.gov/34851696
Autor:
J.S. Rockel, H. Fetter Filippini, E. Wasilewski, M.M. Lewis-Bakker, S. Gabrial, E. Rossomacha, T. Leroux, H. Clarke, R.P. Bonin, L.P. Kotra, M. Kapoor
Publikováno v:
Osteoarthritis and Cartilage. 30:S309-S310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd1f91ef213f13df15786fff1a9a841
https://doi.org/10.1016/j.joca.2022.02.414
https://doi.org/10.1016/j.joca.2022.02.414
Autor:
Jason S. Rockel, Mohit Kapoor, K. Shestopaloff, S. Nakamura, E. Rossomacha, Starlee Lively, Rajiv Gandhi, P. Potla, Poulami Datta, Chiara Pastrello, Igor Jurisica, Helal Endisha
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100080-(2020)
(246 Words) Objective Osteoarthritis (OA) is a degenerative joint disease with no approved disease modifying therapy. The enzyme autotaxin (ATX) converts lysophoshatidylcholine analogues to lysophosphatidic acid. Systemic inhibition of ATX reduces pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6924fb41b636117f22aeb88f1c448b6
https://pubmed.ncbi.nlm.nih.gov/36474685
https://pubmed.ncbi.nlm.nih.gov/36474685
Autor:
Rajiv Gandhi, A. Nakamura, Nigil Haroon, E. Rossomacha, Kala Sundararajan, Igor Jurisica, Roman Krawetz, Brian Wu, Max Kotlyar, Mohit Kapoor, E. Matip, Yoga Raja Rampersaud, S. Nakamura, Jason S. Rockel
Publikováno v:
Osteoarthritis and cartilage. 29(3)
Summary Objectives To investigate the role of zinc finger protein 440 (ZNF440) in the pathophysiology of cartilage degeneration during facet joint (FJ) and knee osteoarthritis (OA). Methods Expression of ZNF440 in FJ and knee cartilage was determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b82b886b3c17ceff9fe30a62da0d69
https://pubmed.ncbi.nlm.nih.gov/33347923
https://pubmed.ncbi.nlm.nih.gov/33347923
Autor:
G. Tavallaee, Mohit Kapoor, Anirudh Sharma, Helal Endisha, Poulami Datta, Carolen Younan, Rajiv Gandhi, E. Rossomacha, S. Nakamura
Publikováno v:
Oral Presentations.
Background We have previously reported that microRNA-34a (miR-34a) is expressed at significantly higher levels in the synovial fluid of late-stage radiographic knee osteoarthritis (OA) compared to early-stage radiographic knee OA. Despite increased l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::006f61fee58d828b522f123b11f13e9d
https://doi.org/10.1136/annrheumdis-2019-eular.2677
https://doi.org/10.1136/annrheumdis-2019-eular.2677
Publikováno v:
Cartilage, synovium and bone.
Background Beclin-1 is a component of the autophagy pathway necessary for formation of autophagosomes, contributing to autophagy-mediated cellular homeostasis. Enhancing autophagy through inhibition of mTOR activity, either via genetic deletion in ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49e5c023ae8c46ae8cd563d5867f9979
https://doi.org/10.1136/annrheumdis-2019-eular.2680
https://doi.org/10.1136/annrheumdis-2019-eular.2680
Autor:
J. Matelski, Igor Jurisica, Rajiv Gandhi, S.A. Ali, Jason S. Rockel, Boris Hinz, K. Perry, M. Im, A. Ratneswaran, S. Nakamura, Mohit Kapoor, Starlee Lively, E. Rossomacha, G. Tavallaee, S. Gabrial, C. Sarda, P. Potla
Publikováno v:
Osteoarthritis and Cartilage. 29:S124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db1782fc0b95de3db2bee507e4decd6
https://doi.org/10.1016/j.joca.2021.02.174
https://doi.org/10.1016/j.joca.2021.02.174