Zobrazeno 1 - 10
of 234
pro vyhledávání: '"E. Rosser"'
Autor:
Sergey V. Lobanov, Branduff McAllister, Mia McDade-Kumar, G. Bernhard Landwehrmeyer, Michael Orth, Anne E. Rosser, REGISTRY Investigators of the European Huntington’s disease network, Jane S. Paulsen, PREDICT-HD Investigators of the Huntington Study Group, Jong-Min Lee, Marcy E. MacDonald, James F. Gusella, Jeffrey D. Long, Mina Ryten, Nigel M. Williams, Peter Holmans, Thomas H. Massey, Lesley Jones
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Huntington’s disease is caused by an expanded CAG tract in HTT. The length of the CAG tract accounts for over half the variance in age at onset of disease, and is influenced by other genetic factors, mostly implicating the DNA maintenance
Externí odkaz:
https://doaj.org/article/471abbf3af654a65a0a60f88b8f7af52
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundIrritable and impulsive behaviour are common in Huntington’s disease (HD: an autosomal dominant disorder causing degeneration in cortico-striatal networks). However, the cognitive mechanisms underlying these symptoms remain unclear, and p
Externí odkaz:
https://doaj.org/article/6128aa2da4d24ba3a146e6b3d873333b
Autor:
Emma Yhnell, Hannah Furby, Rachel S. Lowe, Lucy C. Brookes-Howell, Cheney J. G. Drew, Rebecca Playle, Gareth Watson, Claudia Metzler-Baddeley, Anne E. Rosser, Monica E. Busse
Publikováno v:
Pilot and Feasibility Studies, Vol 6, Iss 1, Pp 1-14 (2020)
Abstract Background Huntington’s disease (HD) is associated with a range of cognitive deficits including problems with executive function. In the absence of a disease modifying treatment, cognitive training has been proposed as a means of slowing c
Externí odkaz:
https://doaj.org/article/6d320a1348fe40c0b0c76567fab036e3
Autor:
Chiara Casella, Elena Kleban, Anne E. Rosser, Elizabeth Coulthard, Hugh Rickards, Fabrizio Fasano, Claudia Metzler-Baddeley, Derek K. Jones
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102658- (2021)
White matter (WM) alterations have been identified as a relevant pathological feature of Huntington’s disease (HD). Increasing evidence suggests that WM changes in this disorder are due to alterations in myelin‐associated biological processes. Mu
Externí odkaz:
https://doaj.org/article/d652a201ca654acd8e553655c2b3b878
Autor:
Cristina Salado-Manzano, Unai Perpiña, Marco Straccia, Francisco J. Molina-Ruiz, Emanuele Cozzi, Anne E. Rosser, Josep M. Canals
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Neurodegenerative disorders such as Parkinson’s (PD) and Huntington’s disease (HD) are characterized by a selective detrimental impact on neurons in a specific brain area. Currently, these diseases have no cures, although some promising trials of
Externí odkaz:
https://doaj.org/article/df6680de93984f5c9159b4eb1ccd0efd
Autor:
Sophie V. Precious, Gaynor A. Smith, Andreas Heuer, Ines Jaeger, Emma L. Lane, Stephen B. Dunnett, Meng Li, Claire M. Kelly, Anne E. Rosser
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Neural transplantation in neurodegenerative diseases such as Parkinson’s disease (PD) offers to replace cells lost during the progression of the disease process. Primary fetal ventral mesencephalon (VM), the origin of bona fide midbrain dopaminergi
Externí odkaz:
https://doaj.org/article/b68b33a606d4496d942f58d2fff9423c
Autor:
Emma Yhnell, Hannah Furby, Rachel S. Breen, Lucy C. Brookes-Howell, Cheney J. G. Drew, Rebecca Playle, Gareth Watson, Claudia Metzler-Baddeley, Anne E. Rosser, Monica E. Busse
Publikováno v:
Pilot and Feasibility Studies, Vol 4, Iss 1, Pp 1-11 (2018)
Abstract Background Cognitive impairments, especially deficits of executive function, have been well documented as a core and early feature in Huntington’s disease (HD). Cognitive impairments represent considerable burden and can be devastating for
Externí odkaz:
https://doaj.org/article/823142ac6d234a7b8246aac6f6c2a382
Autor:
Sofia Marchesini, Benjamen P. Reed, Helen Jones, Lidija Matjacic, Timothy E. Rosser, Yundong Zhou, Barry Brennan, Mariavitalia Tiddia, Rhodri Jervis, Melanie. J. Loveridge, Rinaldo Raccichini, Juyeon Park, Andrew J. Wain, Gareth Hinds, Ian S. Gilmore, Alexander G. Shard, Andrew J. Pollard
Publikováno v:
ACS Applied Materials & Interfaces. 14:52779-52793
Lithium-ion batteries are the most ubiquitous energy storage devices in our everyday lives. However, their energy storage capacity fades over time due to chemical and structural changes in their components, via different degradation mechanisms. Under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b0b0b6114b719567772ba65ec19d3a
https://doi.org/10.1021/acsami.2c13636
https://doi.org/10.1021/acsami.2c13636
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The basal ganglia are implicated in a wide range of motor, cognitive and behavioral activities required for normal function. This region is predominantly affected in Huntington's disease (HD), meaning that functional ability progressively worsens. Ho
Externí odkaz:
https://doaj.org/article/0505d47ca95447ccaab9cd5b3546b86a
Autor:
David J. Harrison, Victoria H. Roberton, Ngoc-Nga Vinh, Simon P. Brooks, Stephen B. Dunnett, Anne E. Rosser
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Huntington's disease (HD) is a progressive neurodegenerative disease in which striatal medium spiny neurons (MSNs) are lost. Neuronal replacement therapies aim to replace MSNs through striatal transplantation of donor MSN progenitors, which successfu
Externí odkaz:
https://doaj.org/article/37735d1079ca490b8c3cc13d9b9eebdd