Zobrazeno 1 - 10
of 227
pro vyhledávání: '"E. Richard Moxon"'
Autor:
Ryan G. Hames, Zydrune Jasiunaite, Giuseppe Ercoli, Joseph J. Wanford, David Carreno, Kornelis Straatman, Luisa Martinez-Pomares, Hasan Yesilkaya, Sarah Glenn, E. Richard Moxon, Peter W. Andrew, Charalambos P. Kyriacou, Marco R. Oggioni
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Circadian rhythms affect the progression and severity of bacterial infections including those caused by Streptococcus pneumoniae, but the mechanisms responsible for this phenomenon remain largely elusive. Following advances in our understanding of th
Externí odkaz:
https://doaj.org/article/c49b1d7d8c5e40b6ad0433ab37204ae2
Autor:
David Carreno, Joseph J Wanford, Zydrune Jasiunaite, Ryan G. Hames, Wen Y Chung, Ashley R. Dennison, Kornelis Straatman, Luisa Martinez-Pomares, Manish Pareek, Carlos J. Orihuela, Marcos I. Restrepo, Wei Shen Lim, Peter W. Andrew, E. Richard Moxon, Marco R Oggioni
Publikováno v:
EBioMedicine, Vol 72, Iss , Pp 103601- (2021)
Background: Severe community-acquired pneumococcal pneumonia is commonly associated with bacteraemia. Although it is assumed that the bacteraemia solely derives from pneumococci entering the blood from the lungs it is unknown if other organs are impo
Externí odkaz:
https://doaj.org/article/e46599f8a665416fbe5eedc6ff8f5c32
Autor:
Charlene M.C. Rodrigues, Jay Lucidarme, Ray Borrow, Andrew Smith, J. Claire Cameron, E. Richard Moxon, Martin C.J. Maiden
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 4, Pp 673-682 (2018)
In September 2015, 4CMenB meningococcal vaccine was introduced into the United Kingdom infant immunization program without phase 3 trial information. Understanding the effect of this program requires enhanced surveillance of invasive meningococcal di
Externí odkaz:
https://doaj.org/article/51f8d8e8518346738f25f7c3d8ce08e1
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The discovery of vaccine antigens through whole genome sequencing (WGS) contrasts with the classical hypothesis-driven laboratory-based analysis of microbes to identify components to elicit protective immunity. This radical change in scientific direc
Externí odkaz:
https://doaj.org/article/f37a97e57ecc441a9076e5ea33204d9f
Autor:
Ashley R. Dennison, Peter W. Andrew, Kornelis Straatman, David Carreno, Kevin West, Joseph J. Wanford, Wen Yuan Chung, Robeena Farzand, Luisa Martinez-Pomares, Vincenzo Di Pilato, Mariagrazia Pizza, M. R. Oggioni, Fabio Arena, E. Richard Moxon, Zydrune Jasiunaite, Ryan G Hames, Gian Maria Rossolini
Publikováno v:
The Lancet Microbe, Vol 2, Iss 12, Pp e695-e703 (2021)
Klebsiella, macrophage, abscess Background: Hypervirulent Klebsiella pneumoniae (hvKp) strains of capsule type K1 and K2 cause invasive infections associated with hepatic abscesses, which can be difficult to treat and are frequently associated with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b74d7116e13d2cc9e994e1f67105129
http://www.sciencedirect.com/science/article/pii/S2666524721001956
http://www.sciencedirect.com/science/article/pii/S2666524721001956
Autor:
Derek W. Hood, E. Richard Moxon
Lipopolysaccharide (LPS) is a critical, if not essential, component of the cell wall of gram-negative bacteria. Through lipid A functioning as a bacterial endotoxin and the saccharide portion contacting host cell surfaces, LPS is responsible for many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608a0933ac1fcb18cbe0536a8cebb539
https://doi.org/10.1201/9781003064961-3
https://doi.org/10.1201/9781003064961-3
Autor:
Christopher D. Bayliss, Jonathan C. Holmes, Joseph J. Wanford, Marco R. Oggioni, Megan De Ste Croix, E. Richard Moxon
Publikováno v:
Molecular Microbiology
Bottlenecks reduce the size of the gene pool within populations of all life forms with implications for their subsequent survival. Here, we examine the effects of bottlenecks on bacterial commensal‐pathogens during transmission between, and dissemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043604963c807b7e92afe5c89a127c0a
http://hdl.handle.net/11585/797703
http://hdl.handle.net/11585/797703
Autor:
Wen Yuan Chung, E. Richard Moxon, Ashley R. Dennison, Marcos I. Restrepo, Luisa Martinez-Pomares, Wei Shen Lim, Joseph J. Wanford, Carlos J. Orihuela, Ryan G Hames, M. R. Oggioni, Manish Pareek, David Carreno, Zydrune Jasiunaite, Kornelis Straatman, Peter W. Andrew
Publikováno v:
EBioMedicine, Vol 72, Iss, Pp 103601-(2021)
EBioMedicine
EBioMedicine
Background Severe community-acquired pneumococcal pneumonia is commonly associated with bacteraemia. Although it is assumed that the bacteraemia solely derives from pneumococci entering the blood from the lungs it is unknown if other organs are impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e45b4972a7bb8d561d007fc4e5f1bf
https://doi.org/10.1016/j.ebiom.2021.103601
https://doi.org/10.1016/j.ebiom.2021.103601
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
The discovery of vaccine antigens through whole genome sequencing (WGS) contrasts with the classical hypothesis-driven laboratory-based analysis of microbes to identify components to elicit protective immunity. This radical change in scientific direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b42d87d4fdcd3d2b7ef1a9bb8c5222
https://doi.org/10.3389/fimmu.2019.00751
https://doi.org/10.3389/fimmu.2019.00751
Autor:
David Carreno, E. Richard Moxon, Zydrune Jasiunaite, Joseph J. Wanford, Ryan G Hames, Marco R. Oggioni, Marcos I. Restrepo, Carlos J. Orihuela, Peter W. Andrew
Publikováno v:
Access Microbiology. 1
During bacteremic pneumonia, the prevailing dogma is that bacteria seed from the lungs into the blood. Recently, we have shown that experimental murine sepsis is preceded by intracellular replication within splenic macrophages (Ercoli Nat Microbiol 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc3622d3378060464dfc217fd17e2e1c
https://doi.org/10.1099/acmi.ac2019.po0352
https://doi.org/10.1099/acmi.ac2019.po0352