Zobrazeno 1 - 10 of 190 pro vyhledávání: '"E. Ravina"'
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Conformationally Constrained Butyrophenones with Affinity for Dopamine (D1, D2, D4) and Serotonin (5-HT2A, 5-HT2B, 5-HT2C) Receptors: Synthesis of Aminomethylbenzo[b]furanones and Their Evaluation as Antipsychotics
Autor: E. Ravina, José A. Fontenla, Maria Villazon, Maria J. Enguix, M. Isabel Loza, Isabel Casariego, M. Isabel Cadavid, Christian F. Masaguer, Maria E. Rivas, Gian Carlo Demontis, Gisela Y. Montenegro
Publikováno v: Journal of Medicinal Chemistry. 43:4678-4693
A series of novel conformationally restricted butyrophenones (6-aminomethyl-4,5,6,7-tetrahydrobenzo[b]furan-4-ones bearing 4-(6-fluorobenzisoxazolyl)piperidine, 4-(p-fluorobenzoyl)piperidine, 4-(o-methoxyphenyl)piperazine, 4-(2-pyridyl)piperazine, 4-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f615dda9837d1415aad5ae5efad9dedc
https://doi.org/10.1021/jm0009890
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4
Synthesis and Affinities for Dopamine (D2) and 5-Hydroxytryptamine (5-HT2A Receptors of 1-(Benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)- piperazines as Cyclic Butyrophenone Derivatives
Autor: Isabel Loza, Angeles Honrubia, Christian F. Masaguer, María L. de Ceballos, Jose Cid, Tomas G-Ferreiro, J. A. Fontenla, Jesus Negreira, J. M. Calleja, E. Ravina, Javier Fueyo, Helena Tristan, Elizabeth Rosa
Publikováno v: Chemical and Pharmaceutical Bulletin. 44:534-541
Starting from benzo- or thienocycloalkaneacetic acids, we have prepared a series of 1-(3-p-fluorobenzoylpropyl)-4-(1-oxo-benzo- or thienocycloalkyl-2-ethyl)piperazines 8a-e containing both semirigid and linear butyrophenones pharmacophores. The affin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc2658860525b7b55f9dd18fe6d44b2
https://doi.org/10.1248/cpb.44.534
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