Zobrazeno 1 - 9
of 9
pro vyhledávání: '"E. Randal Hofmann"'
Autor:
E. Randal Hofmann, Charles Davidson, Hsiu Chen, Melody Zacharko, Jay E. Dorton, Gary K. Kilper, Carcie Graves, Aleksandr E. Miklos, Katherine Rhea, Joe Ma, Bruce G. Goodwin, Shanmuga Sozhamannan
Publikováno v:
ACS Omega, Vol 6, Iss 35, Pp 22700-22708 (2021)
Externí odkaz:
https://doaj.org/article/26b62111d1cc44f5ba260d4c0b741c1c
Autor:
Melody Zacharko, Charles E. Davidson, Aleksandr E. Miklos, Hsiu Chen, Bruce G. Goodwin, Jay E. Dorton, Katherine A. Rhea, Joe Ma, Gary K. Kilper, Carcie Graves, Shanmuga Sozhamannan, E. Randal Hofmann
Publikováno v:
ACS Omega, Vol 6, Iss 35, Pp 22700-22708 (2021)
ACS Omega
ACS Omega
Lateral flow immunoassays (LFIs) are simple, point-of-care diagnostic devices used for detecting biological agents or other analytes of interest in a sample. LFIs are predominantly singleplex assays, interrogating one target analyte at a time. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0615dbb477b5dcb4a3867670886f544
https://doaj.org/article/26b62111d1cc44f5ba260d4c0b741c1c
https://doaj.org/article/26b62111d1cc44f5ba260d4c0b741c1c
Autor:
Ralf Eberhard, Lilli Stergiou, E Randal Hofmann, Jen Hofmann, Simon Haenni, Youjin Teo, André Furger, Michael O Hengartner
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003943 (2013)
Synthesis of ribosomal RNA by RNA polymerase I (RNA pol I) is an elemental biological process and is key for cellular homeostasis. In a forward genetic screen in C. elegans designed to identify DNA damage-response factors, we isolated a point mutatio
Externí odkaz:
https://doaj.org/article/c7284247b0d14aea90b926ee7d59d43f
Publikováno v:
Journal of Microbiological Methods. 152:143-147
Phages are natural predators of bacteria and have been exploited in bacterial detection because of their exquisite specificity to their cognate bacterial hosts. In this study, we present a “proof of concept” bacteriophage amplification-coupled as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2d17dfe4c72bed8ca5f3498e828aed
https://doi.org/10.1016/j.mimet.2018.07.022
https://doi.org/10.1016/j.mimet.2018.07.022
Phages are natural predators of bacteria and have been exploited in bacterial detection because of their exquisite specificity to their cognate bacterial hosts. In this study, we present a bacteriophage amplification-coupled assay as a surrogate for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f89ce5efb5277d81a826b1c6a80d45a
https://doi.org/10.1101/318071
https://doi.org/10.1101/318071
Autor:
Oliver Hobert, Zvi Fuks, E Randal Hofmann, Xinzhu Deng, Bayard D. Clarkson, Michael O. Hengartner, Luis Campodonico, Athanasios Glekas, Alberto Villanueva, Xianglei Yin, Paola Capodieci, Darren R. Veach, Carlos Cordon-Cardo, William Bornmann, Richard Kolesnick
Publikováno v:
Nature Genetics. 36:906-912
c-Abl, a conserved nonreceptor tyrosine kinase, integrates genotoxic stress responses, acting as a transducer of both pro- and antiapoptotic effector pathways. Nuclear c-Abl seems to interact with the p53 homolog p73 to elicit apoptosis. Although sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a39ccbe683dcaacf881a125734b7e3a
https://doi.org/10.1038/ng1396
https://doi.org/10.1038/ng1396
Autor:
Joseph G. Culotti, Patricia W. Greenwell, Thomas D. Petes, Lijia Zhang, Natasha P. Degtyareva, Michael O. Hengartner, E. Randal Hofmann
Publikováno v:
Proceedings of the National Academy of Sciences. 99:2158-2163
Mismatch repair genes are important in maintaining the fidelity of DNA replication. To determine the function of the Caenorhabditis elegans homologue of the MSH2 mismatch repair gene ( msh-2 ), we isolated a strain of C. elegans with an insertion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7dabf2651a0c0f77d9d9134b85d529
https://doi.org/10.1073/pnas.032671599
https://doi.org/10.1073/pnas.032671599
Autor:
Björn, Schumacher, Momoyo, Hanazawa, Min-Ho, Lee, Sudhir, Nayak, Katrin, Volkmann, E Randal, Hofmann, Randall, Hofmann, Michael, Hengartner, Tim, Schedl, Anton, Gartner
Publikováno v:
Cell. 122(1)
Summaryp53 is a tumor suppressor gene whose regulation is crucial to maintaining genome stability and for the apoptotic elimination of abnormal, potentially cancer-predisposing cells. C. elegans contains a primordial p53 gene, cep-1, that acts as a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca56db59da4bd4382ad942e85baa7ec6
Autor:
Jen Hofmann, Ralf Eberhard, Lilli Stergiou, E. Randal Hofmann, Simon Haenni, Youjin Teo, Andre Furger, Michael O. Hengartner
Publikováno v:
PLoS genetics
PLoS Genetics
PLoS Genetics, Vol 9, Iss 11, p e1003943 (2013)
PLoS Genetics
PLoS Genetics, Vol 9, Iss 11, p e1003943 (2013)
Synthesis of ribosomal RNA by RNA polymerase I (RNA pol I) is an elemental biological process and is key for cellular homeostasis. In a forward genetic screen in C. elegans designed to identify DNA damage-response factors, we isolated a point mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6eac84cbad4152e6c3bb7e1e4f386b1