Zobrazeno 1 - 10
of 25
pro vyhledávání: '"E. R. Main"'
Publikováno v:
Journal of biological physics. 27(2-3)
The folding pathway of FKBP12, a 107 residue α/β protein, has been characterised in detail using a combination of experimental and computational techniques. FKBP12 follows a two-state model of folding in which only the denatured and native states a
Autor:
E R, Main, S E, Jackson
Publikováno v:
Nature structural biology. 6(9)
Nonaqueous co-solvents, particularly 2,2,2-trifluoroethanol (TFE), have been used as tools to study protein folding. By analyzing FKBP12, an alpha/beta-protein that folds with two-state kinetics, we have been able to address three key questions conce
Autor:
E. R. Main, Arthur Locke
Publikováno v:
Journal of Infectious Diseases. 43:41-59
Publikováno v:
The Journal of Immunology. 36:183-192
Summary The capacity for retarding the proliferation of type I pneumococci penetrating to the circulating blood is augmented during fever, through a largely thermal effect; during recovery from sub-fatal type I pneumococcal infection, as a result of
Publikováno v:
Journal of Infectious Diseases. 39:126-140
The amount of protein associated with one hemolytic unit in an amboceptor serum is ordinarily not less than 0.04 mg. This has been reduced by electro-dialytic fractionation 1 to 0.002 mg., and by fractional adsorption2 to 0.000,125 mg. The best fract
Autor:
E. R. Main, Arthur Locker
Publikováno v:
Journal of Infectious Diseases. 43:420-425
A method is suggested, herewith, for the approximation of the Lo equivalent of diphtheria toxin preparations by means of a modified flocculation titration.1 The method comprises, in its essence, the estimation of the L, unit and the unit flocculation
Autor:
Arthur Locke, E. R. Main
Publikováno v:
The Journal of Immunology. 36:173-181
Summary and Conclusions Susceptibility to fatal shock following histamine injection, in the rabbit, is intensified following pretreatment with caffeine, thyroid, vitamin B and cortin: agents capable of producing augmentation of capacity to respond to
Autor:
E. R. Main, Arthur Locke
Publikováno v:
Journal of Biological Chemistry. 64:75-80
Autor:
A. Locke, E. R. Main
Publikováno v:
Journal of Infectious Diseases. 39:484-490
Autor:
Arthur Locke, E. R. Main
Publikováno v:
Journal of Infectious Diseases. 46:393-404
Cellular respiration can hardly be maintained and conditioned through the activity of a single catalyst, containing but one metal, iron. It more probably involves a successful balance between the catalytic potentialities of several metals, in several