Zobrazeno 1 - 10 of 15 pro vyhledávání: '"E. R. Lazarowski"'
1
Thrombin-promoted release of UDP-glucose from human astrocytoma cells
Autor: S M, Kreda, L, Seminario-Vidal, C van, Heusden, E R, Lazarowski
Publikováno v: British journal of pharmacology. 153(7)
The P2Y14 receptor is activated by UDP-sugars, most potently by UDP-glucose, but not by free nucleotides, suggesting that UDP-glucose is the cognate agonist for this receptor. However, evidence for regulated release of UDP-glucose is scarce. In the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ca69ac13b58811a97429addc9aaf7f6
https://pubmed.ncbi.nlm.nih.gov/18204471
Zobrazit plný text záznamu
2
Effect of protein kinase A on inositide metabolism and rap 1 G-protein in human erythroleukemia cells
Autor: Deborah A. Winegar, E Oberdisse, R D Nolan, E R Lazarowski, Eduardo G. Lapetina
Publikováno v: Journal of Biological Chemistry. 265:13118-13123
Human erythroleukemia (HEL) cells phosphorylate [3H]inositol 1,4,5-trisphosphate to inositol 1,3,4,5-tetrakisphosphate; they also contain all the enzymes to sequentially dephosphorylate [3H]inositol 1,4,5-trisphosphate and [3H]inositol 1,3,4,5-tetrak
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::962a3b3dfc8db705e0ff6b93f26d5660
https://doi.org/10.1016/s0021-9258(19)38274-2
Zobrazit plný text záznamu
3
Cloning and functional characterization of two murine uridine nucleotide receptors reveal a potential target for correcting ion transport deficiency in cystic fibrosis gallbladder
Autor: E R, Lazarowski, L G, Rochelle, W K, O'Neal, C M, Ribeiro, B R, Grubb, V, Zhang, T K, Harden, R C, Boucher
Publikováno v: The Journal of pharmacology and experimental therapeutics. 297(1)
Extracellular nucleotides regulate transepithelial ion secretion via multiple receptors. The P2Y(2) receptor is the predominant transducer of chloride transport responses to nucleotides in the airways, but the P2 receptors that control ion transport
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e47ea9aa73f6cdf8f0cf67878ea6d0ad
https://pubmed.ncbi.nlm.nih.gov/11259526
Zobrazit plný text záznamu
4
Basal nucleotide levels, release, and metabolism in normal and cystic fibrosis airways
Autor: S H, Donaldson, E R, Lazarowski, M, Picher, M R, Knowles, M J, Stutts, R C, Boucher
Publikováno v: Molecular medicine (Cambridge, Mass.). 6(11)
BACKGROUND: Cystic fibrosis (CF) is a syndrome caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene. Despite advances in our understanding of the molecular pathogenesis of CF, the link between CFTR gene mutations and the pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca08a1e29c458617a5a6a1c6a5271495
https://pubmed.ncbi.nlm.nih.gov/11147574
Zobrazit plný text záznamu
5
ATP release by mechanically loaded porcine chondrons in pellet culture
Autor: R D, Graff, E R, Lazarowski, A J, Banes, G M, Lee
Publikováno v: Arthritis and rheumatism. 43(7)
To determine whether ATP is released from chondrocytes during mechanical stimulation and whether degradation of ATP generates inorganic pyrophosphate in chondron pellet cultures.Chondron pellets were formed from 1.6 x 10(6) cells that had been enzyma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2b530a7792363d21e9f2ccbbc56dcbc
https://pubmed.ncbi.nlm.nih.gov/10902762
Zobrazit plný text záznamu
7
Cystic fibrosis transmembrane regulator-independent release of ATP. Its implications for the regulation of P2Y2 receptors in airway epithelia
Autor: W C, Watt, E R, Lazarowski, R C, Boucher
Publikováno v: The Journal of biological chemistry. 273(22)
The cystic fibrosis (CF) transmembrane regulator (CFTR) is a cyclic AMP-dependent Cl- channel that is defective in CF cells. It has been hypothesized that CFTR exhibits an ATP release function that controls the airway surface ATP concentrations. In a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::51b2e5ecbb510852b3e5eb6fc1ef0233
https://pubmed.ncbi.nlm.nih.gov/9593757
Zobrazit plný text záznamu
9
Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor
Autor: R A, Nicholas, W C, Watt, E R, Lazarowski, Q, Li, K, Harden
Publikováno v: Molecular pharmacology. 50(2)
Observation that the G protein-coupled P2U receptor (P2Y2 receptor) is activated by UTP as well as ATP provided the first indication that a class of uridine nucleotide-responsive receptors might exist. This hypothesis was confirmed by our identificat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1cebc8b0cb4909f6ad3d667da7dd0d57
https://pubmed.ncbi.nlm.nih.gov/8700127
Zobrazit plný text záznamu
10
Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C
Autor: E R, Lazarowski, T K, Harden
Publikováno v: The Journal of biological chemistry. 269(16)
Incubation of C6-2B rat glioma cells with UDP or UTP resulted in a time- and concentration-dependent increase in the accumulation of inositol phosphates. In contrast, ATP, ADP, and analogs of these nucleotides known to be effective agonists at P2U-,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7bf091d8b214ae0b4534b5ddfdd4ec18
https://pubmed.ncbi.nlm.nih.gov/8163481
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje